Curtis Fedorchuk, Douglas Frank Lightstone, Robert DeVon Comer, Evan Katz, Justin Wilcox
Cervical spondylolisthesis indicates instability of the spine and can lead to pain, radiculopathy, myelopathy and vertebral artery stenosis. Currently degenerative cervical spondylolisthesis is a wait-and-watch condition with no treatment guidelines. A literature review and discussion will be provided. 8 females presented with neck pain, disability, and history of motor vehicle collision. Radiographs revealed abnormal cervical alignment, spinal canal narrowing, and spondylolistheses. After 30 sessions of Chiropractic BioPhysics® care over 12 weeks, patients reported improved symptoms and disabilities...
April 2020: Journal of Radiology Case Reports
Gökay Çetinkaya, Ramazan Kozan, Ahmet Cihangir Emral, Ekmel Tezel
BACKGROUND: Idiopathic granulomatous mastitis (IGM) is a benign and rare chronic inflammatory disease of the breast with unknown etiology. While there is no consensus regarding its post-diagnosis management, there are different treatment alternatives. AIMS: In this study, it was aimed to question the effectiveness of follow-up strategy without administering any treatment. METHODS: One hundred eighteen female patients diagnosed with IGM were retrospectively evaluated...
October 20, 2020: Irish Journal of Medical Science
Ashish Kumar, Monil Majmundar, Rajkumar Doshi, Tikal Kansara, Mariam Shariff, Palak Shah, Devina Adalja, Nageshwara Gullapalli, Saraschandra Vallabhajosyula, Sidakpal S Panaich, Vinod H Thourani
The main objective was to determine the optimal strategy for managing asymptomatic severe aortic stenosis (AS) between early intervention versus conservative management. We performed a systematic electronic search of the PubMed and Cochrane databases from the inception of the database to May 31st , 2020. The Mantel Haenszel method with the Paule-Mandel estimator of Tau2 and Hartung-Knapp adjustment were used to calculate relative risk (RR) with a 95% confidence interval (CI) and 95% prediction interval (PI)...
October 13, 2020: American Journal of Cardiology
Amer Shakil, Kimberly Aparicio, Elizabeth Barta, Kristal Munez
Groin hernias are caused by a defect of the abdominal wall in the groin area and comprise inguinal and femoral hernias. Inguinal hernias are more common in men. Although groin hernias are easily diagnosed on physical examination in men, ultrasonography is often needed in women. Ultrasonography is also helpful when a recurrent hernia, surgical complication after repair, or other cause of groin pain (e.g., groin mass, hydrocele) is suspected. Magnetic resonance imaging has higher sensitivity and specificity than ultrasonography and is useful for diagnosing occult hernias if clinical suspicion is high despite negative ultrasound findings...
October 15, 2020: American Family Physician
Michal Manisterski, Marganit Benish, Dror Levin, Shelly I Shiran, Osnat Sher, Yair Gortzak, Ronit Elhasid
BACKGROUND: Infantile myofibromatosis (IM) is a rare benign fibrous tumor with diverse clinical presentations and treatments, such as watchful waiting, surgical excision, and low-dose chemotherapy. PROCEDURE: Clinical presentation and tailored treatment of five infants with solitary and generalized IM are described, together with a review of the literature. RESULTS: Three patients underwent total-body magnetic resonance imaging (MRI) at diagnosis and during follow up, which revealed disease extension that aided in designing treatment...
October 16, 2020: Pediatric Blood & Cancer
Ibrahim S Almazrua, Abdullah Y Almarshad, Ghadah Binzuman, Anwar M Alrabiah
Introduction: Psoas hematoma is an uncommon complication following spinal surgeries. It has been reported in both extreme lateral interbody fusion (XLIF) and posterior spinal fusion with instrumentation. Minimally invasive techniques are gaining popularity in recent years due to the appealing advantages of reduced operative time, blood loss, hospital stay, and faster recovery. Case Presentation: We are presenting a case of a 77-year-old male with chronic low back pain, diagnosed to have multilevel degenerative disc disease with central and foraminal disc protrusion at L2-L3, L3-L4, L4-L5 with secondary spinal stenosis, underwent XLIF at L3-L4, L4-L5 and then 2nd stage with posterior L3-L5 fusion with pedicle screws...
2020: Orthopedic Research and Reviews
Koos Korsten, Niels Adriaenssens, Samuel Coenen, Christopher Butler, Behnaz Ravanfar, Heather Rutter, Julie Allen, Ann Falsey, Jean-Yves Pirçon, Olivier Gruselle, Vincent Pavot, Charlotte Vernhes, Sunita Balla-Jhagjhoorsingh, Deniz Öner, Gabriela Ispas, Jeroen Aerssens, Vivek Shinde, Theo Verheij, Louis Bont, Joanne Wildenbeest
BACKGROUND: Respiratory syncytial virus (RSV) infection in older adults is recognized as an important health issue. We aimed to assess the community burden of RSV in Europe in older adults aged ≥60 years. METHODS: This international prospective observational cohort study is part of REspiratory Syncytial virus Consortium in EUrope (RESCEU). Participants were recruited before two independent RSV-seasons through general practitioner's offices. Participants reported weekly about symptoms of acute respiratory tract infection (ARTI) during one RSV-season...
October 15, 2020: European Respiratory Journal
Miyuki Shoho, Akira Kuriyama
Acute renal failure with severe loin pain and patchy renal ischemia after anaerobic exercise (ALPE) is gradually gaining recognition. In this case series, we describe the presentation of ALPE in the emergency department setting and its clinical course. In Case 1, an 18-year-old man presented with acute-onset nausea, vomiting, and right flank pain after playing basketball, with a creatinine level of 6.42 mg/dL on initial presentation. He received fluid therapy and intravenous furosemide for 2 days. His creatinine level was 1...
October 7, 2020: American Journal of Emergency Medicine
Tim J Hartung, Ida Rask Moustsen, Signe Benzon Larsen, Elisabeth A Wreford Andersen, Nis P Suppli, Christoffer Johansen, Anne Tjønneland, Anne S Friberg, Susanne K Kjær, Klaus Brasso, Lars V Kessing, Anja Mehnert, Susanne Oksbjerg Dalton
PURPOSE: To estimate the risk of first-time antidepressant prescriptions as a proxy for depression or anxiety and associated risk factors in patients with prostate cancer and their female partners. METHODS: We followed all men (n = 25,126) and their female cohabiting partners (n = 8785) without a history of cancer or antidepressants from the Danish Diet, Cancer and Health cohort from 1997 to 2014 or 2010, respectively. We estimated the cumulative incidence of first-time antidepressant prescriptions in men with prostate cancer compared with cancer-free men and their respective female partners, using the Danish National Prescription Registry...
October 13, 2020: Journal of Cancer Survivorship: Research and Practice
Manette A W Dinnessen, Marjolein W M van der Poel, Sanne H Tonino, Otto Visser, Nicole M A Blijlevens, Daphne de Jong, King H Lam, Marie José Kersten, Pieternella J Lugtenburg, Avinash G Dinmohamed
We assessed stage-specific trends in primary therapy and relative survival among adult follicular lymphoma (FL) patients diagnosed in the Netherlands between 1989-2016 (N = 12,372; median age, 62 years; and 21% stage I disease). Patients were stratified by disease stage and subsequently categorized into four calendar periods (1989-1995, 1996-2002, 2003-2008, and 2009-2016) and three age groups (18-60, 61-70, and >70 years). The use of radiotherapy in stage I FL remained relatively stable over time and across the three age groups (i...
October 12, 2020: Leukemia
Tim Strand, Sari Kives, Nicholas Leyland, John Ashkenas, Peter Janiszewski, John Thiel
OBJECTIVES: To describe treatment choices made at the time of enrollment in CAPTURE, a Canadian patient registry for women with symptomatic uterine fibroids (UFs), and to define demographic and clinical characteristics that independently predict these choices. METHODS: Women arranging appointments for UF care were eligible to enrol. At the time of the enrollment visit, women's self-reported treatment histories were noted, along with their clinical characteristics...
July 2, 2020: Journal of Obstetrics and Gynaecology Canada: JOGC
Cynthia L Forrest, Ana Verzone
BACKGROUND: Overuse of antibiotics leads to antibiotic resistance, costing $35 billion and causing approximately 23,000 deaths in the United States annually. Antibiotic stewardship is important in urgent care centers to prevent antibiotic resistance. LOCAL PROBLEM: Providers prescribed antibiotics to 80% of patients with viral conditions at this urgent care center. The aim of this quality improvement (QI) project was to improve right care for patients of 65 years and younger with upper respiratory infections and/or head, ears, nose, or throat viral illnesses presenting to urgent care from 36...
October 7, 2020: Journal of the American Association of Nurse Practitioners
Antonio Caycedo-Marulanda, Sunil V Patel, Chris P Verschoor, Johanna P Uscategui, Sami A Chadi, Gabriela Moeslein, Manish Chand, Yasuko Maeda, John R T Monson, Steven D Wexner, Julio Mayol
BACKGROUND: Management of rectal cancer has a number of potentially appropriate alternatives for each patient. Despite acceptance of standards, practices may vary among regions. There is significant paucity of data in this area. The objective was to create a snapshot of the regional differences. DESIGN: This online survey included 10 questions. Enquiries focused on controversial topics, on surgeon and hospital volume, surgical margins, appropriateness of surgical approaches and techniques, watch-and-wait strategies, and total neoadjuvant therapy...
October 8, 2020: World Journal of Surgery
Carolyn G Mazariego, Sam Egger, Madeleine T King, Ilona Juraskova, Henry Woo, Martin Berry, Bruce K Armstrong, David P Smith
OBJECTIVE: To assess treatment related changes in quality of life up to 15 years after diagnosis of localised prostate cancer. DESIGN: Population based, prospective cohort study with follow-up over 15 years. SETTING: New South Wales, Australia. PARTICIPANTS: 1642 men with localised prostate cancer, aged less than 70, and 786 controls randomly recruited from the New South Wales electoral roll into the New South Wales Prostate Cancer Care and Outcomes Study (PCOS)...
October 7, 2020: BMJ: British Medical Journal
Atif Hassan, Barry F Uretsky, Andres M Vargas Estrada, Romesa Hassan, Malek Al-Hawwas, Shiv Kumar Agarwal
Pseudoaneurysm (PSA) formation is a rare but well-known complication of coronary stenting. It develops after a procedural perforation disrupts the integrity of the vessel wall but is contained by a single wall layer, usually pericardium, extravascular thrombosis and later fibrosis. Medical literature of PSA consists primarily of case reports. A systematic review of pseudoaneurysm after coronary stenting was performed to summarize its presentation, diagnostic imaging modalities, natural history, and management approaches...
October 5, 2020: Catheterization and Cardiovascular Interventions
Antonio Pea, Lulu Tanno, Taina Nykänen, Pooja Prasad, Ceren Tunçer, Stuart Robinson, Giovanni Marchegiani
Pancreatic neuroendocrine tumors (PanNETs) are rare tumors but incidence is increasing. An increasing number of these tumors are diagnosed incidentally when they are small (<2 cm) and when patients are asymptomatic. The European Neuroendocrine Tumor Society (ENETS) recommends conservative watch and wait policy for these patients. However, best surgical approach (parenchyma-sparing or formal oncological resection) for these small tumors when surgery is indicated is currently unknown. Parenchyma-sparing resections such as enucleation is associated with higher risk of post-operative morbidity compared to formal oncological resections...
2020: Frontiers in Medicine
Andrew J Gogos, Jacob S Young, Matheus P Pereira, Ramin A Morshed, Matthew B Potts, Shawn L Hervey-Jumper, Mitchel S Berger
OBJECTIVE: Although most patients with low-grade glioma (LGG) present after a seizure, a small proportion is diagnosed after neuroimaging is performed for a sign or symptom unrelated to the tumor. While these tumors invariably grow, some surgeons argue for a watchful waiting approach. Here, the authors report on their experience in the surgical treatment of patients with incidental LGG (iLGG) and describe the neurological outcomes, survival, and complications. METHODS: Relevant cases were identified from a prospective registry of patients undergoing glioma resection at the University of California, San Francisco, between 1997 and 2019...
October 2, 2020: Journal of Neurosurgery
Jan Herden, Andreas Schwarte, Thorsten Werner, Uwe Behrendt, Axel Heidenreich, Lothar Weissbach
PURPOSE: To report on long-term outcomes of patients treated with active surveillance (AS) for localized prostate cancer (PCa) in the daily routine setting. METHODS: HAROW (2008-2013) was a non-interventional, health service research study about the management of localized PCa in the community setting, with 86% of the study centers being office-based urologists. A follow-up examination of all patients who opted for AS as primary treatment was carried out. Overall, cancer-specific, and metastasis-free survival, as well as discontinuation rates, were determined...
September 30, 2020: World Journal of Urology
Fatima Domenica Elisa De Palma, Gaetano Luglio, Francesca Paola Tropeano, Gianluca Pagano, Maria D'Armiento, Guido Kroemer, Maria Chiara Maiuri, Giovanni Domenico De Palma
The response to neoadjuvant chemoradiation (nCRT) is a critical step in the management of locally advanced rectal cancer (LARC) patients. Only a minority of LARC patients responds completely to neoadjuvant treatments, thus avoiding invasive radical surgical resection. Moreover, toxic side effects can adversely affect patients' survival. The difficulty in separating in advances responder from non-responder patients affected by LARC highlights the need for valid biomarkers that guide clinical decision-making...
September 24, 2020: International Journal of Molecular Sciences
Ravi B Parikh, Kyle W Robinson, Sumedha Chhatre, Elina Medvedeva, John P Cashy, Shika Veera, Joshua M Bauml, Tito Fojo, Amol S Navathe, S Bruce Malkowicz, Ronac Mamtani, Ravishankar Jayadevappa
Importance: Conservative management (ie, active surveillance or watchful waiting) is a guideline-based strategy for men with low-risk and intermediate-risk prostate cancer. However, use of conservative management is controversial for African American patients, who have worse prostate cancer outcomes compared with White patients. Objective: To examine the association of African American race with the receipt and duration of conservative management in the Veterans Health Administration (VA), a large equal-access health system...
September 1, 2020: JAMA Network Open
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