Kieran Seay, Tracey Akanbi, Bethany Bustamante, Shweta Chaudhary, Gary L Goldberg
Introduction: Mesonephric-like adenocarcinoma (MLA) is a rare malignant gynecologic neoplasm occurring in the uterine corpus and ovary. The morphological and immunohistochemical characteristics of MLA closely resemble that of cervical mesonephric adenocarcinomas, but whether they share a common histogenesis remains unclear. Two main theories for histogenesis of MLAs include the origination of these neoplasms from mesonephric remnants, as is the case for cervical mesonephric adenocarcinoma, versus the differentiation along a mesonephric pathway from Mullerian lesions...
November 2020: Gynecologic Oncology Reports
Mohamed Beghdad, Amine Mkhatri, Yassine Harmoumi, Meriem Doumiri, Sami Rouadi, Reda Abada, Mohamed Roubal, El Benna Naima, Mohamed Mahtar
Undifferentiated nasopharyngeal cancer of the cavum (UCNT) is the most frequent neoplasm of the nasopharynx, having a close relationship with exposure to Epstein-Barr virus. It has a high potential for locoregional or distant invasion which are the cause of some treatment failures. The extension to the maxillary sinus is rarely described. We report here the case of a 38-year-old patient with headaches associated with epistaxis, left otalgia and facial pain. Examination by anterior rhinoscopy objectively revealed a polylobed ulcerating mass...
2020: Pan African Medical Journal
Yon Hee Kim, Jihyoun Lee
BACKGROUND: A cutaneous ciliated cyst (CCC) is a rare, benign tumor in young female adults, which is usually found on the lower extremities. CASE SUMMARY: We found an uncommon location of CCC in the anterolateral cervical area and reviewed the literature. A 20-year-old female complained of a well-defined, painless, palpable mass that started several years ago. The mass was tense and movable and located at the anterolateral aspect of the neck. Imaging showed a non-enhancing round mass...
October 6, 2020: World Journal of Clinical Cases
Yaron Drori, Jasmine Jacob-Hirsch, Rakefet Pando, Aharona Glatman-Freedman, Nehemya Friedman, Ella Mendelson, Michal Mandelboim
Influenza viruses and respiratory syncytial virus (RSV) are respiratory viruses that primarily circulate worldwide during the autumn and winter seasons. Seasonal surveillance has shown that RSV infection generally precedes influenza. However, in the last four winter seasons (2016-2020) an overlap of the morbidity peaks of both viruses was observed in Israel, and was paralleled by significantly lower RSV infection rates. To investigate whether the influenza A virus inhibits RSV, human cervical carcinoma (HEp2) cells or mice were co-infected with influenza A and RSV...
October 16, 2020: Viruses
Ramachandran Govindasamy, Veeramani Preethish-Kumar, Swaroop Gopal, Satish Rudrappa
BACKGROUND: The treatment of atlantoaxial instability (AAI) involves stable fixation and fusion with adequate decompression of spinal cord. After the advent of the Goel posterior joint manipulation technique, most of the once irreducible atlantoaxial dislocations (AAD) could be reduced and the need for transoral odontoidectomy became almost nil. Here we tried to iterate the indications of anterior transoral odontoid surgery for AAI in the current scenario. METHODS: A retrospective study compiling the clinical, radiological, and surgical characteristics of 6 cases (5 scenarios)...
October 19, 2020: International Journal of Spine Surgery
Maged M Costantine, Grecio Sandoval, William A Grobman, Jennifer L Bailit, Uma M Reddy, Ronald J Wapner, Michael W Varner, John M Thorp, Steve N Caritis, Mona Prasad, Alan T N Tita, Yoram Sorokin, Dwight J Rouse, Sean C Blackwell, Jorge E Tolosa
OBJECTIVE:  This study aimed to develop and validate a model to predict the probability of vaginal delivery (VD) in low-risk term nulliparous patients, and to determine whether it can predict the risk of severe maternal and neonatal morbidity. METHODS:  Secondary analysis of an obstetric cohort of patients and their neonates born in 25 hospitals across the United States ( n  = 115,502). Trained and certified research personnel abstracted the maternal and neonatal records...
October 19, 2020: American Journal of Perinatology
Eliza R C Hagens, Maud A Reijntjes, Martinus C J Anderegg, Wietse J Eshuis, Mark I van Berge Henegouwen, Suzanne S Gisbertz
BACKGROUND: Identifying predictors of anastomotic leakage can contribute to prevention of this common complication after esophagectomy. The objective of this study was to identify predictors for anastomotic leakage and to assess the influence of anastomotic leakage on short-term outcomes and long-term survival. METHODS: A retrospective cohort study was conducted in consecutive patients who underwent esophagectomy in the Amsterdam UMC, location AMC, between 1993 and 2019...
October 16, 2020: Annals of Thoracic Surgery
Dylan J Coss, Wieslawa Tlomak, Elizabeth Cochran
Resorbable topical hemostatic agents are widely used in surgical procedures to control intraoperative bleeding. There have been multiple reports of complications from use of these agents, including pulmonary vasculature thromboembolism, cerebral venous sinus occlusion, and postoperative inflammatory mass lesions each containing the hemostatic agent. We report 2 cases of inadvertent intra-arterial embolization of hemostatic agent. Both cases followed elective surgical cervical spinal procedures, during which gelatin-based local hemostatic agents were used to control unanticipated bleeding...
October 16, 2020: American Journal of Forensic Medicine and Pathology
Mohamed A Bedewi, Mamdouh A Kotb
OBJECTIVES: The objective of this study is to estimate the reference values of the brachial plexus roots at the interscalene groove. The physical and demographic characteristics of 59 healthy adult volunteers were studied. The CSA reference values and their correlations with weight, height, age, body mass index (BMI). METHODS: Fifty nine (27 males, 32 females) subjects were enrolled in the study. The mean cross sectional area of C5, C6 and C7 nerve roots were obtained...
October 19, 2020: Neurological Sciences
Ann M Kulungowski, Manish Patel
Lymphatic malformations are low-flow vascular malformations that arise due to errors in vascular development. Lymphatic malformations are benign and usually noted at birth or in the first few years of life. Lymphatic mass lesions are composed of varying size of cysts; this article focuses on discussion of cystic lymphatic malformations. Lymphatic malformations can occur throughout the body especially in lymphatic rich areas such as the cervical and axillary locations as well as the groin, trunk, retroperitoneum, extremities, abdominal or thoracic cavities...
October 2020: Seminars in Pediatric Surgery
Andreas Kavallaris, Nektarios Chalvatzas, Antonios Gkoutzioulis, Dimitrios Zygouris
PURPOSE: The aim of this study is to evaluate surgical data and oncological outcome of laparoscopic nerve-sparing radical hysterectomy without uterine manipulator for cervical cancer stage IB, over the last 8 years. METHODS: This retrospective study includes 32 patients with cervical cancer Figo stage (2009) IB who underwent laparoscopic nerve-sparing radical hysterectomy without using any kind of uterine manipulator. Patients were eligible if they had squamous cell carcinoma, adenocarcinoma, or adeno-squamous carcinoma, and no para-aortic lymph node involvement by imaging or after frozen section...
October 17, 2020: Archives of Gynecology and Obstetrics
Pelayo Hevia Rodríguez, Joaquín Andermatten, Alejandro Elúa Pinín, Patricia Moreno Moya, Nicolás Samprón, Enrique Úrculo Bareño
We report the case of a 17-year-old male presented to the emergency department with a six weeks history of neck pain and no neurogical deficit. Computed tomography and magnetic resonance imaging revealed an expansile lesion in the axis, with soft tissue and spinal cavity invasion, without mielopathy signs. Tomography-guided mass biopsy was taken. Waiting for histopathologic results, the pacient developed acute tetraparesis and sphincter incompetence. Magnetic resonance revealed that the bone mass had grown with epidural compromise, mielopathy and new vertebral lesions...
October 13, 2020: Neurocirugía
Yinjing Song, Xia Wu, Yaohan Xu, Jiang Zhu, Jiaying Li, Ziqi Zou, Luxia Chen, Boya Zhang, Chunting Hua, Han Rui, Qiaoli Zheng, Qiang Zhou, Qingqing Wang, Hao Cheng
Human papillomavirus (HPV) is a DNA virus that causes sexually transmitted infections. The HPV oncoprotein E7 plays a critical role in the regulation of host immunity to promote the immune escape of HPV and the occurrence of cervical cancer or genital warts. Pyroptosis, a highly inflammatory form of programmed cell death, can be induced by inflammasomes and acts as a defense against pathogenic infection. However, whether HPV E7 can regulate cell pyroptosis to evade immune surveillance has not been determined...
2020: International Journal of Biological Sciences
Shuanghuan Liu, Yunquan Guo, Bin Li, Huijuan Zhang, Rong Zhang, Shan Zheng
Purpose: To avoid misdiagnosis, clinicopathological features were analyzed in cases of cervical mucinous adenocarcinoma with solitary ovarian metastatic masses. Patients and Methods: Three cases misdiagnosed as primary ovarian adenocarcinoma before surgery were filtered from the database of the Cancer Hospital/Chinese Academy of Medical Sciences from January 1998 to December 2016. The clinical data were thoroughly collected and compared, and both frozen and paraffin-embedded pathological sections were reviewed by two expert pathologists...
2020: Cancer Management and Research
Rachid Marouf, Ihsan Alloubi, Brahim Housni
Thymic masses are one of the most common tumors in the anterior mediastinum. Nevertheless, because the thymus originates in the third and fourth pharyngeal pouches and descends into the anterior mediastinum, ectopic thymic tissue may be found anywhere from the angle of the mandible to the superior mediastinum. Ectopic cervical thymoma (ECT) is an extremely rare tumor that originates from ectopic thymic tissue trapped during the migration of the embryonic thymus and is often misdiagnosed as a thyroid tumor or other neck masses...
March 2020: Indian Journal of Thoracic and Cardiovascular Surgery
Reiji Muto, Naoki Uemura, Norikazu Mitsui, Fumiko Arakawa, Takanori Negishi, Hiroaki Miyoshi, Koichi Ohshima, Toshihiko Murayama
This is the first reported case of follicular T-cell lymphoma (FTCL) that primarily developed in the extranodal site of the right submandibular gland. An 86-year-old man was detected with a right cervical mass suspected to be malignant lymphoma during his physical examination. Imaging studies revealed that the mass was a submandibular gland tumor. The tumor was excised for diagnosis and treatment. Pathologically, the tumor was composed of densely aggregated lymphocytes with a follicular growth pattern. The immunohistochemical investigation showed that the lymphoma cells expressed CD3, CD4, programmed cell death protein 1, BCL6, chemokine (C-X-C motif) ligand 13, and BCL2...
October 13, 2020: Pathology International
Andra Nica, Soyoun Rachel Kim, Lilian T Gien, Allan Covens, Marcus Q Bernardini, Geneviève Bouchard-Fortier, Rachel Kupets, Taymaa May, Danielle Vicus, Stephane Laframboise, Liat Hogen, Maria C Cusimano, Sarah Elizabeth Ferguson
OBJECTIVES: Minimally invasive radical hysterectomy is associated with decreased survival in patients with early cervical cancer. The objective of this study was to determine whether the use of an intra-uterine manipulator at the time of laparoscopic or robotic radical hysterectomy is associated with inferior oncologic outcomes. METHODS: A retrospective cohort study was carried out of all patients with cervical cancer (squamous cell carcinoma, adenocarcinoma or adenosquamous carcinoma) International Federation of Gynecology and Obstetrics 2009 stages IA1 (with positive lymphovascular space invasion) to IIA who underwent minimally invasive radical hysterectomy at two academic centers between January 2007 and December 2017...
October 9, 2020: International Journal of Gynecological Cancer
Anna Jacob, Andrea Plaikner, Achim Schneider, Giovanni Favero, Roberto Tozzi, Peter Mallmann, Christian Domröse, Peter Martus, Simone Marnitz, Jana Barinoff, Christhardt Kohler
OBJECTIVE: Lymphadenectomy is an integral part of surgical staging and treatment for patients with gynecologic malignancies. Since its introduction, laparoscopic lymphadenectomy has proved feasible, safe, and oncologically adequate compared with open surgery while morbidity is lower and hospital stay considerably shorter. The aim of this study was to examine if surgical outcomes may be improved after the initial learning curve is complete. METHODS: An analysis of 2535 laparoscopic pelvic and/or para-aortic lymphadenectomies was performed between July 1994 and March 2018 by one team of gynecologic oncology surgeons but with the consistent supervision of a consultant surgeon...
October 9, 2020: International Journal of Gynecological Cancer
F N Korkmaz, A Gokcay Canpolat, B Bilezikci, H Gurkan, M F Erdogan
An 81-year-old woman presented with a history of essential hypertension for eight years and an asymptomatic multinodular goiter that had been incidentally discovered on neck ultrasonography two years ago and an-isohypoechoic mass lesion located adjacent to the right lobe inferior pole of the thyroid gland. Parathyroid adenoma or lymphadenopathy were the differential diagnosis. After two years, the endocrine surgeon decided to operate her multinodular goiter and her probably benign lesion. Intraoperatively, the blood pressure and pulse rate increased markedly and intravenous antihypertensive treatment was administered...
April 2020: Acta endocrinologica: the international journal of the Romanian Society of Endocrinology
Lutgardo García-Díaz, Angel Chimenea, Juan Carlos de Agustín, Antonio Pavón, Guillermo Antiñolo
BACKGROUND: The "Ex-Utero Intrapartum Treatment" (EXIT) procedure allows to ensure fetal airway before completion of delivery and umbilical cord clamping while keeping uteroplacental circulation. Airway obstruction in fetal oropharyngeal and cervical masses can be life-threatening at birth. In those situations, controlled access to fetal airway performed by a trained multidisciplinary team allows safe airway management, while feto-maternal circulation is preserved. We aim to review the indications and outcome of the EXIT procedure in a case series of fetal cervical and oropharyngeal masses...
October 7, 2020: BMC Pregnancy and Childbirth
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