Zeynep Akcaoglu, Thomas Vaessen, Eva Velthorst, Ginette Lafit, Robin Achterhof, Barnaby Nelson, Patrick McGorry, Frederike Schirmbeck, Craig Morgan, Jessica Hartmann, Mark van der Gaag, Lieuwe de Haan, Lucia Valmaggia, Philip McGuire, Matthew Kempton, Henrietta Steinhart, Annelie Klippel, Wolfgang Viechtbauer, Tim Batink, Ruud van Winkel, Thérèse van Amelsvoort, Machteld Marcelis, Evelyne van Aubel, Ulrich Reininghaus, Inez Myin-Germeys
BACKGROUND: Psychotic experiences (PEs) and social isolation (SI) seem related during early stages of psychosis, but the temporal dynamics between the two are not clear. Literature so far suggests a self-perpetuating cycle wherein momentary increases in PEs lead to social withdrawal, which, subsequently, triggers PEs at a next point in time, especially when SI is associated with increased distress. The current study investigated the daily-life temporal associations between SI and PEs, as well as the role of SI-related and general affective distress in individuals at clinical high risk (CHR) for psychosis...
January 5, 2024: Psychological Medicine