Ariane Bollack, Lyduine E Collij, David Vállez García, Mahnaz Shekari, Daniele Altomare, Pierre Payoux, Bruno Dubois, Oriol Grau-Rivera, Mercè Boada, Marta Marquié, Agneta Nordberg, Zuzana Walker, Philip Scheltens, Michael Schöll, Robin Wolz, Jonathan M Schott, Rossella Gismondi, Andrew Stephens, Christopher Buckley, Giovanni B Frisoni, Bernard Hanseeuw, Pieter Jelle Visser, Rik Vandenberghe, Alexander Drzezga, Maqsood Yaqub, Ronald Boellaard, Juan Domingo Gispert, Pawel Markiewicz, David M Cash, Gill Farrar, Frederik Barkhof
INTRODUCTION: To support clinical trial designs focused on early interventions, our study determined reliable early amyloid-β (Aβ) accumulation based on Centiloids (CL) in pre-dementia populations. METHODS: A total of 1032 participants from the Amyloid Imaging to Prevent Alzheimer's Disease-Prognostic and Natural History Study (AMYPAD-PNHS) and Insight46 who underwent [18 F]flutemetamol, [18 F]florbetaben or [18 F]florbetapir amyloid-PET were included...
April 4, 2024: Alzheimer's & Dementia: the Journal of the Alzheimer's Association