Alessandra Cassio, Gloria Marescotti, Tommaso Aversa, Mariacarolina Salerno, Gianluca Tornese, Marianna Stancampiano, Gerdi Tuli, Maria Felicia Faienza, Paolo Cavarzere, Daniela Fava, Maria Parpagnoli, Patrizia Bruzzi, Anastasia Ibba, Valeria Calcaterra, Chiara Mameli, Anna Grandone, Valentino Cherubini, Valentina Assirelli, Francesca Franchina, Donatella Capalbo, Raffaella Di Mase, Gianluca Tamaro, Julia Cavasin, Jessica Munarin, Gianni Russo, Malgorzata Wasniewska
CONTEXT: There are only a few nationwide studies on boys with central precocious puberty (CPP) and the last Italian study is a case series of 45 boys that dates back to 2000. OBJECTIVE: We aimed to evaluate the causes of CPP in boys diagnosed during the last 2 decades in Italy and the relative frequency of forms with associated central nervous system (CNS) abnormalities on magnetic resonance imaging (MRI) compared to idiopathic ones. METHODS: We performed a national multicenter retrospective study collecting data from 193 otherwise normal healthy boys with a diagnosis of CPP...
February 3, 2024: Journal of Clinical Endocrinology and Metabolism