keyword
https://read.qxmd.com/read/38702817/feasibility-of-utilizing-mediastinal-drains-alone-following-esophageal-cancer-surgery-a-retrospective-study
#1
JOURNAL ARTICLE
Yu Li, Danjie Zhang, Danwen Zhao
BACKGROUND: It was typically necessary to place a closed thoracic drainage tube for drainage following esophageal cancer surgery. Recently, the extra use of thoracic mediastinal drainage after esophageal cancer surgery had also become more common. However, it had not yet been determined whether mediastinal drains could be used alone following esophageal cancer surgery. METHODS: A total of 134 patients who underwent esophageal cancer surgery in our department between June 2020 and June 2023 were retrospectively analyzed...
May 3, 2024: World Journal of Surgical Oncology
https://read.qxmd.com/read/38701067/transcriptome-profiles-of-trypanosoma-brucei-rhodesiense-in-malawi-reveal-focus-specific-gene-expression-profiles-associated-with-pathology
#2
JOURNAL ARTICLE
Peter Nambala, Harry Noyes, Joyce Namulondo, Oscar Nyangiri, Vincent Pius Alibu, Barbara Nerima, Annette MacLeod, Enock Matovu, Janelisa Musaya, Julius Mulindwa
BACKGROUND: Sleeping sickness caused by Trypanosoma brucei rhodesiense is a fatal disease and endemic in Southern and Eastern Africa. There is an urgent need to develop novel diagnostic and control tools to achieve elimination of rhodesiense sleeping sickness which might be achieved through a better understanding of trypanosome gene expression and genetics using endemic isolates. Here, we describe transcriptome profiles and population structure of endemic T. b. rhodesiense isolates in human blood in Malawi...
May 3, 2024: PLoS Neglected Tropical Diseases
https://read.qxmd.com/read/38700773/investigation-of-thermal-performance-drying-characteristics-and-environomical-analysis-direct-flow-evacuated-tube-solar-drying-of-okra
#3
JOURNAL ARTICLE
Dhiraj Kumar Yadav, Vinkel Kumar Arora, Vikrant Yadav
A direct flow evacuated tube solar dryer (DF_ETSD), a novel drying system, was used for drying pre-treated okra (Abelmoschus esculentus). The performance of DF_ETSD was analysed by determining thermal profiling, dryer and collector efficiency hourly. The maximum 3-day average ambient temperature, collector outlet temperature and solar radiation were 35.6 °C, 66.4 °C and 976 W m-2 respectively. The collector efficiency increased as solar radiation increased over time due to a higher temperature difference between the collector outlet and ambient temperature...
May 3, 2024: Environmental Science and Pollution Research International
https://read.qxmd.com/read/38700422/deep-water-first-occurrences-of-ediacara-biota-prior-to-the-shuram-carbon-isotope-excursion-in-the-wernecke-mountains-yukon-canada
#4
JOURNAL ARTICLE
Thomas H Boag, James F Busch, Jared T Gooley, Justin V Strauss, Erik A Sperling
Ediacara-type macrofossils appear as early as ~575 Ma in deep-water facies of the Drook Formation of the Avalon Peninsula, Newfoundland, and the Nadaleen Formation of Yukon and Northwest Territories, Canada. Our ability to assess whether a deep-water origination of the Ediacara biota is a genuine reflection of evolutionary succession, an artifact of an incomplete stratigraphic record, or a bathymetrically controlled biotope is limited by a lack of geochronological constraints and detailed shelf-to-slope transects of Ediacaran continental margins...
2024: Geobiology
https://read.qxmd.com/read/38700247/effect-of-organic-cation-adsorption-on-ion-transport-selectivity-in-a-cation-permselective-nanopore-membrane
#5
JOURNAL ARTICLE
Thomas T Volta, Stevie N Walters, Charles R Martin
A key knowledge gap in the emerging field of nanofluidics concerns how the ionic composition and ion-transport properties of a nanoconfined solution differ from those of a contacting bulk solution. We and others have been using potentiometric concentration cells, where a nanopore or nanotube membrane separates salt solutions of differing concentrations to explore this issue. The membranes studied contained a fixed pore/tube wall anionic charge, which ideally would prohibit anions and salt from entering the pore/tube-confined solution...
May 3, 2024: Langmuir: the ACS Journal of Surfaces and Colloids
https://read.qxmd.com/read/38698162/the-effect-of-tympanostomy-tubes-on-otoacoustic-emissions
#6
JOURNAL ARTICLE
Aneesh A Patel, Peter C Weber, Jessica R Levi
PURPOSE: Otoacoustic emissions (OAE) are a common screening tool to evaluate cochlear function. Middle ear dysfunction has been shown to impact results of otoacoustic emission testing, but there are limited data on the effect of tympanostomy tubes on OAE. The purpose of this study was to determine whether tympanostomy tube placement significantly improved OAE. METHODS: A retrospective review of charts was completed for patients younger than 18 years old who underwent tympanostomy tube placement from January 1, 2018 to September 1, 2023 and had preoperative and postoperative OAE testing within 6 months of surgery...
May 2, 2024: European Archives of Oto-rhino-laryngology
https://read.qxmd.com/read/38696583/risk-of-meningomyelocele-mediated-by-the-common-22q11-2-deletion
#7
JOURNAL ARTICLE
Keng Ioi Vong, Sangmoon Lee, Kit Sing Au, T Blaine Crowley, Valeria Capra, Jeremiah Martino, Meade Haller, Camila Araújo, Hélio R Machado, Renee George, Bryn Gerding, Kiely N James, Valentina Stanley, Nan Jiang, Kameron Alu, Naomi Meave, Anna S Nidhiry, Fiza Jiwani, Isaac Tang, Ashna Nisal, Ishani Jhamb, Arzoo Patel, Aakash Patel, Jennifer McEvoy-Venneri, Chelsea Barrows, Celina Shen, Yoo-Jin Ha, Robyn Howarth, Madison Strain, Allison Elizabeth Ashley-Koch, Matloob Azam, Sara Mumtaz, Gyang Markus Bot, Richard H Finnell, Zoha Kibar, Ahmed I Marwan, Gia Melikishvili, Hal S Meltzer, Osvaldo M Mutchinick, David A Stevenson, Henry J Mroczkowski, Betsy Ostrander, Erica Schindewolf, Julie Moldenhauer, Elaine H Zackai, Beverly S Emanuel, Sixto Garcia-Minaur, Beata A Nowakowska, Roger E Stevenson, Maha S Zaki, Hope Northrup, Hanna K McNamara, Kimberly A Aldinger, Ian G Phelps, Mei Deng, Ian A Glass, Bernice Morrow, Donna M McDonald-McGinn, Simone Sanna-Cherchi, Dolores J Lamb, Joseph G Gleeson, Allison Elizabeth Ashley Koch, Hal S Meltzer, Joan Le, Kit Sing Au, Hope Northrup, Gyang Markus Bot, Valeria Capra, Richard H Finnell, Zoha Kibar, Philip J Lupo, Helio R Machado, Camila Araújo, Tony Magana, Ahmed I Marwan, Gia Melikishvili, Osvaldo M Mutchinick, Roger E Stevenson, Anna Yurrita, Maha S Zaki, Sara Mumtaz, José Ramón Medina-Bereciartu, Caroline M Kolvenbach, Shirlee Shril, Friedhelm Hildebrandt, Mahmoud M Noureldeen, Aida Ms Salem, Yukitoshi Takahashi, Hormos Salimi-Dafsari, H Westley Phillips, Brian Hanak, Bülent Kara, Ayfer Sakarya Güneş, David D Gonda, Salman Kirmani, Tinatin Tkemaladze, Joseph G Gleeson
Meningomyelocele is one of the most severe forms of neural tube defects (NTDs) and the most frequent structural birth defect of the central nervous system. We assembled the Spina Bifida Sequencing Consortium to identify causes. Exome and genome sequencing of 715 parent-offspring trios identified six patients with chromosomal 22q11.2 deletions, suggesting a 23-fold increased risk compared with the general population. Furthermore, analysis of a separate 22q11.2 deletion cohort suggested a 12- to 15-fold increased NTD risk of meningomyelocele...
May 3, 2024: Science
https://read.qxmd.com/read/38693479/thoracolumbar-fractures-patients-undergoing-posterior-pedicle-screw-fixation-can-benefit-from-drainage
#8
JOURNAL ARTICLE
Jing-Yu Sun, Ning Zhao, Hua Chen, Chun-Hui Chen
PURPOSE: To explore whether it is necessary to put drain tubes after posterior pedicle screw fixation of thoracolumbar fractures. METHODS: From April 2020 to January 2023, a total of 291 patients with recent thoracolumbar fractures (AO type-A or type-B) who received the pedicle screw fixation operation were enrolled retrospectively. In 77 patients, drain tubes were used in the pedicle screw fixation surgery, while no drain tubes were placed in the other group. After gleaning demographic information and results of lab examination and imageology examination, all data were put into a database...
May 1, 2024: BMC Musculoskeletal Disorders
https://read.qxmd.com/read/38693250/percutaneous-cecostomy-25-year-two-institution-experience
#9
JOURNAL ARTICLE
Charles A James, Mark J Hogan, Ryan P Seay, Luke T James, Hanna K Jensen, Nicholas A Kaukis, Mary B Moore, Leah E Braswell
BACKGROUND: Reports of technical success, adverse events, and long-term outcome of percutaneous cecostomy in children are limited. OBJECTIVE: To characterize technical success, 30-day severe adverse events, and long-term outcome of percutaneous cecostomy at two centers. MATERIALS AND METHODS: A retrospective review of hospital course and long-term follow-up (through May 2022) of percutaneous cecostomy tubes placed May 1997 to August 2011 at two children's hospitals was used...
May 2, 2024: Pediatric Radiology
https://read.qxmd.com/read/38689360/bio-efficacy-of-olyset-%C3%A2-plus-permanet-%C3%A2-3-0-and-interceptor-%C3%A2-g2-on-pyrethroid-resistant-populations-of-anopheles-gambiae-s-l-prior-to-the-june-2023-net-distribution-campaign-in-benin-west-africa
#10
JOURNAL ARTICLE
David Mahouton Zoungbédji, Germain Gil Padonou, Arthur Sovi, Alphonse Keller Konkon, Albert Sourou Salako, Roseric Azondékon, Aboubakar Sidick, Juvénal Minassou Ahouandjinou, Linda Towakinou, Razaki Ossè, Rock Aïkpon, Cyriaque Affoukou, Lamine Baba-Moussa, Martin Akogbéto
BACKGROUND: This study investigates the effectiveness of new-generation mosquito nets, like Olyset® Plus and PermaNet® 3.0, and dual-action nets such as Interceptor® G2, against pyrethroid-resistant Anopheles gambiae mosquitoes following the 2023 mass distribution of long-lasting insecticidal nets in Benin. METHODS: We tested wild mosquito populations from six communes in Benin against various pyrethroid (permethrin 0.75%, alphacypermethrin 0.05%, and deltamethrin 0...
April 30, 2024: Tropical Medicine and Health
https://read.qxmd.com/read/38688338/collagen-sponge-scaffolds-loaded-with-trichostatin-a-pretreated-bmscs-derived-exosomes-regulate-macrophage-polarization-to-promote-skin-wound-healing
#11
JOURNAL ARTICLE
Tingyu Wang, Yuanye Xue, Wenwen Zhang, Zetai Zheng, Xinsheng Peng, Yanfang Zhou
The process of wound healing includes the inflammatory stage, which plays an important role. Macrophages can promote inflammatory response and also promote angiogenesis, wound contraction and tissue remodeling required for wound healing. It is crucial to promote macrophages to polarize from M1 pro-inflammatory phenotype to M2 anti-inflammatory phenotype at a critical time for the quality of wound healing. Because mesenchymal stem cell-derived exosomes have broad therapeutic prospects in the field of tissue repair and regeneration, in this study, we explored whether trichostatin A pretreated bone marrow mesenchymal stem cells (BMSCs)-derived exosomes (T-Exo) could promote wound healing by binding to biomaterial scaffolds through certain anti-inflammatory effects...
April 28, 2024: International Journal of Biological Macromolecules
https://read.qxmd.com/read/38686650/three-point-star-deoxyribonucleic-acid-tiles-with-the-core-arm-length-at-three-half-turns-for-two-dimensional-archimedean-tilings-and-beyond
#12
JOURNAL ARTICLE
Wei Ge, Yantong Wang, Shou-Jun Xiao
2D Archimedean tiling and complex tessellation patterns assembled from soft materials including modular DNA tiles have attracted great interest because of their specific structures and potential applications in nanofabrication, nanoelectronics, nanophotonics, biomedical sensing, drug delivery, therapeutics, etc. Traditional three- and four-point-star DNA tiles with the core arm length at two half-turns (specified as three- and four-point-star-E previously and abbreviated as 3PSE and 4PSE tiles here) have been applied to assemble intricate tessellations through tuning the size of inserted n T ( n = 1-7, T is thymine) loops on helper strands at the tile center...
April 30, 2024: Langmuir: the ACS Journal of Surfaces and Colloids
https://read.qxmd.com/read/38683645/bond-topology-of-chain-ribbon-and-tube-silicates-part-ii-geometrical-analysis-of-infinite-1d-arrangements-of-to-4-n-tetrahedra
#13
JOURNAL ARTICLE
Maxwell Christopher Day, Frank Christopher Hawthorne, Ali Rostami
In Part I of this series, all topologically possible 1-periodic infinite graphs (chain graphs) representing chains of tetrahedra with up to 6-8 vertices (tetrahedra) per repeat unit were generated. This paper examines possible restraints on embedding these chain graphs into Euclidean space such that they are compatible with the metrics of chains of tetrahedra in observed crystal structures. Chain-silicate minerals with T = Si4+ (plus P5+ , V5+ , As5+ , Al3+ , Fe3+ , B3+ , Be2+ , Zn2+ and Mg2+ ) have a grand nearest-neighbour ⟨T-T⟩ distance of 3...
May 1, 2024: Acta Crystallographica. Section A, Foundations and Advances
https://read.qxmd.com/read/38681097/assessment-of-average-glandular-dose-in-mammography-practice-of-a-teaching-hospital-in-ghana
#14
JOURNAL ARTICLE
Kofi Adesi Kyei, Samuel Anim-Sampong, Eugene Nartey Ahulu, William Kwadwo Antwi, Joseph Daniels
INTRODUCTION: above the age of 40, women are advised to begin breast examinations and screenings for early detection of breast cancer. The average glandular dose (AGD) provides dosimetric information about the quantity of radiation received by the mammary glands during mammographic exposures. There is, therefore, the need to analyse the radiation dose received by patients presenting for mammography examinations. METHODS: a retrospective cross-sectional design was carried out on the data of 663 participants, conveniently sampled between the months of July 2021 and June 2022...
2024: Pan African Medical Journal
https://read.qxmd.com/read/38680744/endovascular-resolution-of-post-surgical-complications-in-the-portal-vein-report-of-two-cases
#15
José Sebastián Sotelo Cuéllar, Verónica Andrea Del Pilar Barón Hernández, Alfredo Padilla Martínez, Edy Omar Salazar Hernández, Roberto Carlos Villanueva Escobar, Cesar Orlando Vidal López
Stenosis of the portal vein is one of the main complications after hepatobiliar and pancreatic surgery, with a reported incidence of 19.6% after pancreaticoduodenectomy and 3% after liver transplant. It is associated with the intraoperative resection of the portal vein, local recurrence of the primary tumor and radiotherapy. The portal lesion secondary to bile drainage catheter insertion is extremely rare or unusual, with few cases described in the literature. This article describes 2 cases: the first of a male patients 49 years old post-operative to liver transplant with partial portal thrombosis and stenosis of the mesoportal joint, and the second a female patient 50 years old with history of cholecystectomy, exploration of the bile duct and placement of Kehr "T" tube with secondary portal lesion...
July 2024: Radiology Case Reports
https://read.qxmd.com/read/38679779/aberrant-dorsal-nerve-root-as-a-concomitant-cause-of-spinal-cord-tethering-associated-with-a-dorsal-type-lipomyelomeningocele-in-a-child-with-caudal-agenesis
#16
JOURNAL ARTICLE
O Baskurt, T Hicdonmez, M N Gazioglu
Tethered cord syndrome is a neurological disorder closely associated with congenital spinal dysraphism. Aberrant dorsal nerve roots may be one of the possible and relatively rare tethering pathologies, especially in the complex form of occult spinal dysraphism such as caudal regression syndrome or split cord malformation. We report an illustrative case of caudal regression syndrome with spinal cord tethering due to a combination of a contiguous bundle of an aberrant dorsal nerve root, and a dorsal-type lipomyelomeningocele, with a thickened filum terminale treated with microneurosurgical untethering...
April 1, 2024: Nigerian Journal of Clinical Practice
https://read.qxmd.com/read/38678984/serology-and-molecular-genetic-analysis-of-two-unrelated-individuals-with-the-same-novel-cisab-blood-type
#17
JOURNAL ARTICLE
Tongtong Li, Yongqiang Shan, Xinhua Zhou, Ying Zhao, Lina Wu, Xian Huang, Yang Yang, Jinhui Xie, Jinghui Chong
OBJECTIVE: This study aims to report two unrelated individuals with the same novel CisAB blood type and confirm this rare blood type using a comprehensive approach that combines serological and molecular biology techniques. METHODS: Peripheral blood samples were collected from two patients and their family members. ABO blood typing and antibody detection were performed using conventional tube methods. Molecular biology techniques were employed to amplify and sequence the 6th and 7th exons of the ABO gene, with reference to gene mutation databases provided by NCBI and ISBT...
April 25, 2024: Transfusion and Apheresis Science
https://read.qxmd.com/read/38677376/critically-evaluating-the-role-for-postoperative-antibiotics-in-patients-undergoing-urethroplasty-with-buccal-mucosa-graft-a-claims-database-analysis
#18
JOURNAL ARTICLE
Logan Galansky, Andrew T Gabrielson, Andrew J Cohen
OBJECTIVES: To compare outcomes among patients undergoing first-time urethroplasty with buccal mucosa graft (BMG) who receive post-operative antibiotics versus those who do not. METHODS: A retrospective cohort study was conducted using the TriNetX claims database between 2008-2022. Using CPT, ICD10, and LOINC codes, patients >18 years old undergoing primary urethroplasty with BMG who received an outpatient prescription for antibiotics between post-operative day 0-30 or did not were queried...
April 25, 2024: Urology
https://read.qxmd.com/read/38676898/a-dynamic-sheep-model-to-induce-pulmonary-hypertension-and-right-ventricular-failure
#19
JOURNAL ARTICLE
Carl A Johnson, Michael Cortelli, Gabriella Glomp, Courtney Cagnolatti, Caitlin T Demarest, Rei Ukita, Matthew Bacchetta
Decompensated right ventricular failure (RVF) in pulmonary hypertension (PH) is fatal, with limited medical treatment options. Developing and testing novel therapeutics for PH requires a clinically relevant large animal model of increased pulmonary vascular resistance and RVF. This manuscript describes the method to induce an ovine PH-RVF model that utilizes left pulmonary artery (LPA) ligation, progressive main pulmonary artery (MPA) banding, and insertion of an RV pressure line for monitoring. The PA cuff and RV pressure tubing are connected to subcutaneous access ports...
2024: Methods in Molecular Biology
https://read.qxmd.com/read/38666173/comparison-of-insertion-characteristics-of-lma-proseal-from-the-front-and-head-end-of-the-patient-a-randomized-pilot-study
#20
JOURNAL ARTICLE
Rashmi Salhotra, Kushal Thakkar, Rajesh Singh Rautela, Jainendra Chauhan, S Ajeeb
BACKGROUND AND AIMS: LMA ProSeal (PLMA) is a commonly used airway maintenance device in elective procedures and is routinely inserted from the head-end of the patient. It is also used in pre-hospital emergencies where it may not always be possible to access the head-end. This study aims to compare the insertion characteristics of PLMA when inserted while standing, either at the head-end or from the front. MATERIAL AND METHODS: After institutional ethics committee approval, 60 consenting patients of either sex, between 18 and 60 years, ASA class I/II, and scheduled to undergo elective surgeries were randomly allocated to either group H (head-end insertion) or group F (front-end insertion)...
2024: Journal of Anaesthesiology, Clinical Pharmacology
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