Mengchen Qin, Rouxuan Ou, Weiyi He, Haoyang Han, Yuxue Zhang, Yan Huang, Zhaohan Chen, Xiaoyan Pan, Yali Chi, Songqi He, Lei Gao
INTRODUCTION: Non-healing wounds resulting from trauma, surgery, and chronic diseases annually affect millions of individuals globally, with limited therapeutic strategies available due to the incomplete understanding of the molecular processes governing tissue repair and regeneration. Salvianolic acid B (Sal B) has shown promising bioactivities in promoting angiogenesis and inhibiting inflammation. However, its regulatory mechanisms in tissue regeneration remain unclear. PURPOSE: This study aims to investigate the effects of Sal B on wound healing and regeneration processes, along with its underlying molecular mechanisms, by employing zebrafish as a model organism...
March 29, 2024: Phytomedicine