Amira Awadalla, Hassan Abol-Enein, Eman T Hamam, Asmaa E Ahmed, Salma M Khirallah, Ahmed El-Assmy, Sally Abdallah Mostafa, Ahmed O Babalghith, Mohamed Ali, Mona Abdel-Rahim, Ahmed A Shokeir, Ahmed M Harraz
Purpose: To identify the role of a set of microRNAs and their target genes and protein expression levels in the pathogenesis of bladder cancer with a muscular invasion (T2-T4) and non-muscular invasion (T1). Methods: In 157 patients, bladder specimen was examined for the expression of a set of miRNAs including let-7a-5p, miRNA-449a-5p, miRNA-145-3P, miRNA-124-3P, miRNA-138-5p, and miRNA-23a-5p and their targeted genes; β-catenin , WNT7A , IRS2 , FZD4 , SOS1 , HDAC1 , HDAC2 , HIF1α , and PTEN using the qRT-PCR technique...
September 10, 2022: Genes