Jiayu Liu, Guangyong Wu, Yongan Jiang, Lei Li, Dongliang Wang, Ruen Liu
No abstract text is available yet for this article.
August 30, 2020: World Neurosurgery
Pelin Kuzucu, Tolga Türkmen, Göktuğ Ülkü, Mesut Emre Yaman, Şükrü Aykol
OBJECTIVES: Hyperactive dysfunction syndrome (HDS) is defined as symptoms arising from overactivities in cranial nerves, like trigeminal neuralgia (TN), hemifacial spasm (HFS), and glossopharyngeal neuralgia (GPN). A combination of these cranial nerve neuralgias, that might or might not occur in one or both sides, either synchronously, or metachronously is called combined hyperactive dysfunction syndrome (CHDS). CASE PRESENTATION: We presented a 73 years-old male patient with CHDS presenting with GPN as the initial symptom, with total relief from GPN, TN, and HFS after microvascular decompression...
September 11, 2020: British Journal of Neurosurgery
Byung-Chul Son
We report a very rare case in which a patient believed to have auriculotemporal neuralgia due to the repeated recurrence of paroxysmal stabbing pain in the preauricular temporal region for four years developed occipital neuralgia, which finally improved with decompression of the greater occipital nerve (GON). The pain of occipital neuralgia has been suggested to be referred to the frontoorbital (V1) region through trigeminocervical interneuronal connections in the trigeminal spinal nucleus. However, the reports of such cases are very rare...
2020: Case Reports in Neurological Medicine
Iulia Peciu-Florianu, Jean Régis, Marc Levivier, Michaela Dedeciusova, Nicolas Reyns, Constantin Tuleasca
INTRODUCTION: Trigeminal neuralgia (TN) secondary to tumors is encountered in up to 6% of patients with facial pain syndromes and is considered to be associated with tumors affecting the trigeminal nerve pathways. The most frequent are meningiomas and vestibular schwannomas (VS). Stereotactic radiosurgery (SRS) has emerged as a valuable treatment, with heterogeneity of clinical results. We sought to review the medical literature on TN treated with SRS for meningiomas and VS and investigate the rates of improvement of TN symptoms...
September 9, 2020: Stereotactic and Functional Neurosurgery
Takuro Inoue, Satoshi Shitara, Yukihiro Goto, Mustaqim Prasetya, Takanori Fukushima
BACKGROUND: Separation of the vertebrobasilar artery (VBA) from the trigeminal nerve root in microvascular decompression (MVD) is technically challenging. This study aimed to review the clinical features of VBA involvement in trigeminal neuralgia and evaluate surgical decompression techniques in the long term. METHODS: We retrospectively reviewed the surgical outcomes of 26 patients (4.4%) with VBA involvement in 585 consecutive MVDs for TGN using a Teflon roll for repositioning the VBA...
September 8, 2020: Acta Neurochirurgica
Jeffrey Jon Mojica, Vinay Kudur, Rudy Garza Iii, Maxim S Eckmann
BACKGROUND AND OBJECTIVES: Mandibular nerve blocks are indicated for atypical face pain and trigeminal neuralgia. We hypothesized that a modified lateral approach, which entailed a combination of lateral and anterior approach techniques to the mandibular nerve block would lead to similar efficacy and improved safety profile rather than the typical lateral or anterior techniques. METHODS: This alternative approach was derived from anatomical investigation using the Radiology Anatomy Atlas Viewer and reconstructed axial cadaveric slices...
September 7, 2020: Regional Anesthesia and Pain Medicine
Vincenzo Lupo, Seongsik Won, Marina Frasquet, Megan S Schnitzler, Sneha S Komath, Samuel I Pascual-Pascual, Carmen Espinós, John Svaren, Teresa Sevilla
BACKGROUND: Mutations in the early growth response 2 gene (EGR2) cause demyelinating, but also axonal, neuropathies differing in severity and age of onset. Except for one family, all reported cases have autosomal dominant inheritance and mutations are localized within the three zinc-finger (ZNF) DNA-binding domain. METHODS: Clinical and electrophysiological assessments of three affected patients, from a consanguineous family, were performed. Genetic analyses of EGR2 was carried out by Sanger sequencing...
September 8, 2020: European Journal of Neurology
Biniyam Alemayehu Ayele, Abenet Tafesse Mengesha, Yared Zenebe Zewde
BACKGROUND: Trigeminal neuralgia (TN) is considered one of the most painful illnesses known to medical practice. Little is known about TN in Ethiopia. Our study aimed to assess clinical characteristics, treatment, and associated factors of TN. METHOD: A cross-sectional study was conducted on a total of 61 patients with confirmed Trigeminal neuralgia visiting outpatient neurology clinics of two government teaching Hospitals and two private health facilities in Addis Ababa, Ethiopia between June 2019 and March 2020...
September 3, 2020: BMC Oral Health
Chuan Zhang, Hai Hu, Sushant K Das, Mao-Jiang Yang, Bing Li, Yang Li, Xiao-Xue Xu, Han-Feng Yang
AIMS: To evaluate the available literature on structural and functional brain abnormalities in trigeminal neuralgia (TN) using several brain magnetic resonance imaging (MRI) techniques to further understand the central mechanisms of TN. METHODS: PubMed and Web of Science databases and the reference lists of identified studies were searched to identify potentially eligible studies through January 2019. Eligible articles were assessed for risk of bias and reviewed by two independent researchers...
July 2020: Journal of Oral & Facial Pain and Headache
Yeow Hoay Koh, Yao-Chia Shih, Soo Lee Lim, Yen San Kiew, Ee Wei Lim, See Mui Ng, Leon Qi Rong Ooi, Wen Qi Tan, Yiu-Cho Chung, Helmut Rumpel, Eng King Tan, Ling Ling Chan
OBJECTIVES: Simultaneous multi-slice (SMS) imaging with short repetition time (TR) accelerates diffusion tensor imaging (DTI) acquisitions. However, its impact when combined with readout-segmented echo planar imaging (RESOLVE) on the cranial nerves given the challenging skull base/posterior fossa terrain is unexplored. We evaluated the reliability of trigeminal nerve DTI metrics using SMS with RESOLVE-DTI. METHODS: Eight healthy controls and six patients with unilateral trigeminal neuralgia (TN) underwent brain MRI scan...
September 1, 2020: European Radiology
M-A Louges, J-C Kleiber, A Bazin, A Chays, X Dubernard
OBJECTIVES: Analysis of the long-term efficacy of microvascular decompression surgery in trigeminal neuralgia. MATERIAL AND METHODS: A single-center retrospective study included patients undergoing microvascular decompression surgery for trigeminal neuralgia after failure of well-conducted medical or complementary therapy, with visualization of nerve compression syndrome on MRI. RESULTS: Eighty-seven patients were included. Nerve compression was alleviated without interposition of polytetrafluoroethylene in 79...
September 2020: European Annals of Otorhinolaryngology, Head and Neck Diseases
Jaisan Islam, Elina Kc, Byeong Ho Oh, Soochong Kim, Sang-Hwan Hyun, Young Seok Park
BACKGROUND: Previous studies have reported that electrical stimulation of the motor cortex is effective in reducing trigeminal neuropathic pain; however, the effects of optical motor cortex stimulation remain unclear. OBJECTIVE: The present study aimed to investigate whether optical stimulation of the primary motor cortex can modulate chronic neuropathic pain in rats with infraorbital nerve constriction injury. METHODS: Animals were randomly divided into a trigeminal neuralgia group, a sham group, and a control group...
August 26, 2020: Journal of Headache and Pain
A Sirko, K Chekha, K Mizyakina
In this article, we reviewed neurovascular conflicts of most cranial nerves with characteristic clinical syndromes and analyzed preferred treatment strategies, including surgical methods. We conducted literature review using the Pubmed database, selecting articles on cranial nerves compression syndromes, published for 10 years (from 2010 to 2020). The analysis covered all articles with information on the etiology, pathogenesis, clinical findings, diagnosis, differential diagnosis, neuroimaging, and pathomorphological assessment, as well as treatment strategies for such pathology, including surgical methods...
June 2020: Georgian Medical News
Anouk Borg, Ludvic Zrinzo
No abstract text is available yet for this article.
August 11, 2020: World Neurosurgery
Yonghui Jiao, Li Cai, Guilherme H W Ceccato, Guoqiang Chen, Xiaosong Wang
Trigeminal neuralgia is a cause of severe facial pain, usually provoked by a neurovascular conflict, commonly involving the superior cerebellar artery (SCA).1 The superior petrosal venous complex is in the way toward the nerve through a retrosigmoid approach and can narrow the working area around trigeminal nerve.2-4 Nonetheless, instead an obstacle it can be faced in selected cases as an adjunct to help to transpose the offending arterial loop, avoiding undesired venous sacrifice. We present a case of a 64-year-old male with left sided severe shock-like pain in the V3 territory suggestive of trigeminal neuralgia...
August 11, 2020: World Neurosurgery
John-Ih Lee, Theresa Böcking, Dagny Holle-Lee, Rayaz A Malik, Bernd C Kieseier, Hans-Peter Hartung, Rainer Guthoff, Christoph Kleinschnitz, Mark Stettner
Background: The diagnosis of trigeminal neuralgia (TN) is challenging due to the lack of objective diagnostics. Corneal confocal microscopy (CCM) is a non-invasive ophthalmic imaging technique, which allows quantification of corneal nerve fibers arising from the trigeminal ganglion and may allow the assessment of neurodegeneration in TN. Methods: CCM was undertaken in 11 patients with TN and 11 age-matched healthy controls. Corneal nerve fiber density (CNFD), corneal nerve branch density, corneal nerve fiber length (CNFL), corneal nerve fiber width, corneal nerve fiber area, and dendritic cell and non-dendritic cell density with or without nerve fiber contact were quantified...
2020: Frontiers in Neurology
Giulia Di Stefano, Gianfranco De Stefano, Caterina Leone, Giorgio Cruccu, Stefano Tardioli, Gaia Cartocci, Marco Fiorelli, Andrea Truini, Francesca Caramia
INTRODUCTION: Trigeminal neuralgia is an exemplary neuropathic pain condition characterized by paroxysmal electric-shock-like pain. However, up to 50% of patients also experiences concomitant continuous pain. In this neuroimaging study, we aimed to identify the specific anatomical features of trigeminal nerve root in patients with concomitant continuous pain. METHODS: We enrolled 73 patients with a definitive diagnosis of classical and idiopathic trigeminal neuralgia and 40 healthy participants...
August 13, 2020: Cephalalgia: An International Journal of Headache
Victor Silva, Miles Day, Margarita Santiago
Trigeminal neuralgia (TN) is the most common cause of facial pain, leading to significant disability and impacting a patient´s quality of life. Percutaneous procedures like continuous radiofrequency (CRF), pulsed radiofrequency (PRF) and combined continuous and pulsed (CCPRF) have been studied in past years comparing different voltages in order to find more effective therapies with fewer complications, i.e. numbness and masseter muscle weakness. With regards to young patients, there is still insufficient evidence on the most appropriate procedure in this patient population...
August 13, 2020: Pain Practice: the Official Journal of World Institute of Pain
Taylor Anne Wilson, Bengt Karlsson, Lei Huang, Dinesh Ramanathan, Udochukwu Oyoyo, Warren Boling
OBJECTIVES: Radiosurgery is an increasingly popular treatment for trigeminal neuralgia (TN); however, several treatment variables require further study. This meta-analysis was conducted to clarify ambiguity in the current literature and optimize treatment parameters. METHODS: A random-effects proportions meta-analysis using subgroup analysis and meta-regression investigated the association of prescription dose and anatomic target on outcomes in patients with typical TN...
August 3, 2020: World Neurosurgery
Vidzhai Dzhafarov, Jamil Rzaev, Galina Moysak, Eugenia Voronina
Background: Facial pain resembling trigeminal neuralgia is not a common clinical feature of cervical spinal cord tumor. Depending on nature of the facial pain, differential diagnosis tends to include neurovascular conflict, multiple sclerosis, cerebellopontine angle tumors, herpes zoster, facial injuries, and other conditions involving trigeminal nerve, ganglion, and root. Here, we present a unique case of pain in trigeminal distribution due to an intramedullary tumor in the upper cervical spinal cord...
2020: Surgical Neurology International
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