Ali A Rabaan, Mohammed Garout, Mohammed Aljeldah, Basim R Al Shammari, Abdulsalam Alawfi, Amer Alshengeti, Mustafa A Najim, Mohammed Alrouji, Yasir Almuhanna, Mohammed Alissa, Mutaib M Mashraqi, Ameen S S Alwashmi, Mashael Alhajri, Souad Mohammed Alateah, Ramadan Abdelmoez Farahat, Ranjan K Mohapatra
Tuberculosis (TB), an infectious disease caused by the Mycobacterium tuberculosis (Mtb), has been responsible for the deaths of millions of individuals around the globe. A vital protein in viral pathogenesis known as resuscitation promoting factor (RpfB) has been identified as a potential therapeutic target of anti-tuberculosis drugs. This study offered an in silico process to examine possible RpfB inhibitors employing a computational drug design pipeline. In this study, a total of 1228 phytomolecules were virtually tested against the RpfB of Mtb...
March 24, 2023: Molecular Diversity