Kristýna Štefková-Mazochová, Hynek Danda, Wim Dehaen, Bronislav Jurásek, Klára Šíchová, Nikola Pinterová-Leca, Vladimír Mazoch, Barbora Hrčka Krausová, Bohdan Kysilov, Tereza Smejkalová, Ladislav Vyklický, Michal Kohout, Kateřina Hájková, Daniel Svozil, Rachel R Horsley, Martin Kuchař, Tomáš Páleníček
BACKGROUND AND PURPOSE: Deschloroketamine (DCK), a structural analogue of ketamine, has recently emerged on the illicit drug market as a recreational drug with a modestly long duration of action. Despite it being widely used by recreational users, no systematic research on its effects has been performed to-date. EXPERIMENTAL APPROACH: Pharmacokinetics, acute effects and addictive potential in a series of behavioural tests in Wistar rats were performed following subcutaneous (s...
September 14, 2021: British Journal of Pharmacology