Ruslan Medzhitov, Ethan M Shevach, Giorgio Trinchieri, Andrew L Mellor, David H Munn, Siamon Gordon, Peter Libby, Göran K Hansson, Ken Shortman, Chen Dong, Dmitry Gabrilovich, Leona Gabryšová, Ashleigh Howes, Anne O'Garra
As Nature Reviews Immunology reaches its 10(th) anniversary, the authors of one of the top-cited articles from each year take a trip down memory lane. We've asked them to look back on the state of research at the time their Review was published, to consider why the article has had the impact it has and to discuss the future directions of their field. This Viewpoint article provides an interesting snapshot of some of the fundamental advances in immunology over the past 10 years. Highlights include our improved understanding of Toll-like receptor signalling, and of immune regulation mediated by regulatory T cells, indoleamine 2,3-dioxygenase, myeloid-derived suppressor cells and interleukin-10...
September 23, 2011: Nature Reviews. Immunology