Chieh-Yang Koo, Ai-Ping Chua, William Kristanto, Esther Hui-Ting Koh, Eugene Siang-Joo Tan, Shaffinaz Abd Rahman, Munirah Binte Abd Gani, Jenny Pek-Ching Chong, Aye-Thandar Aung, Tun-Oo Han, Siew-Pang Chan, Adrian F Low, Tiong-Cheng Yeo, Mark Y Chan, Pipin Kojodjojo, Arthur Mark Richards, Chi-Hang Lee
BACKGROUND: We evaluated the effects of sleep-study guided multidisciplinary therapy (SGMT) of obstructive sleep apnoea (OSA) in patients presenting with acute coronary syndrome. METHODS: Eligible patients were randomized into (1) SGMT, comprised a sleep study during the index admission and continuous positive airway pressure and behavioral therapy for those with at least mild OSA or (2) standard therapy. The primary end point was the change in the plasma N-terminal pro-brain natriuretic peptide (NT-proBNP) level from baseline to the 7-month follow-up...
January 15, 2020: International Journal of Cardiology