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thoracic spinal

Saba Pasha, Pedram Hassanzadeh, Malcolm Ecker, Victor Ho
This study aimed to identify the differentiating parameters of the spinal curves' 2D projections through a hierarchical classification of the 3D spinal curve in adolescent idiopathic scoliosis (AIS). A total number of 103 right thoracic left lumbar pre-operative AIS patients were included retrospectively and consecutively. A total number of 20 non-scoliotic adolescents were included as the control group. All patients had biplanar X-rays and 3D reconstructions of the spine. The 3D spinal curve was calculated by interpolating the center of vertebrae and was isotropically normalized...
2019: PloS One
Çağatay Özdöl, Tolga Gediz, Kamran Aghayev
BACKGROUND: Injuries caused by motorcycle accidents have been reported in several studies with an examination from a general trauma point of view. However, to our knowledge, there is no detailed study specific to central nervous system injuries. This research was focused on central nervous system injuries associated with motorcycle accidents. METHODS: The medical records of 540 patients who were admitted to the emergency department between 2008 and 2016 as the result of a motorcycle accident were retrospectively evaluated...
March 2019: Turkish Journal of Trauma & Emergency Surgery: TJTES
R R Dhingra, G Kola, S J Lewis, M Dutschmann
Stimulation of thoracic sympathetic chain (TSC) afferents has been shown to slow the respiratory rhythm in dogs, monkeys and humans. However, sparse information exists about the physiological role of TSC afferents in modulating respiration or the central pathways of these afferents. Here, we sought to investigate whether the perfused preparation of juvenile rats is a suitable experimental model to study the role of TSC-afferents in the modulation of respiration. We show that tonic (30s) TSC stimulation initially triggered either prolonged post-inspiratory vagal nerve discharge, or when the stimulus onset occurred in the second half of expiration, TSC stimulation also modulated late-expiratory abdominal nerve activity...
May 2019: Autonomic Neuroscience: Basic & Clinical
Guohua Shen, Huan Ma, Lili Pan, Minggang Su, Anren Kuang
D-TGCT (diffuse-type tenosynovial giant cell tumor) is a benign proliferative disorder of the synovial membranes that usually occurs in the appendicular skeleton, especially large joints such as the knee, hip, and elbow. It rarely involves the spine. In this report, we describe a rare case of D-TGCT in the thoracic spine, which showed a lytic lesion with high FDG uptake. It can mimic metastases or neurogenic tumors and should be included in the differential diagnosis of spinal tumors.
March 15, 2019: Clinical Nuclear Medicine
Veronica Dusi, Ching Zhu, Olujimi A Ajijola
PURPOSE OF REVIEW: This review aims to describe the latest advances in autonomic neuromodulation approaches to treating cardiac arrhythmias, with a focus on ventricular arrhythmias. RECENT FINDINGS: The increasing understanding of neuronal remodeling in cardiac diseases has led to the development and improvement of novel neuromodulation therapies targeting multiple levels of the autonomic nervous system. Thoracic epidural anesthesia, spinal cord stimulation, stellate ganglion modulatory therapies, vagal stimulation, renal denervation, and interventions on the intracardiac nervous system have all been studied in preclinical models, with encouraging preliminary clinical data...
March 18, 2019: Current Cardiology Reports
Xiao-Miao Zhang, Ludovic Fournel, Audrey Lupo, Emelyne Canny, Antonio Bobbio, Salomé Lasry, Jean-François Regnard, Frederic Sailhan, Marco Alifano
BACKGROUND: Vertebral involvement by a thoracic tumor has long been considered as a limit to surgical treatment, and despite advances, such an invasive surgery remains controversial. The aim of this study was to characterize a single-center cohort, and to evaluate the outcome, focusing on survival and complications. METHODS: We retrospectively reviewed the data of all patients operated on for tumors involving the thoracic spine in an 8-year period. En-bloc resection was generally performed by a double team involving thoracic and orthopedic surgeons...
March 15, 2019: Annals of Thoracic Surgery
Kristen Swieck, Amanda Conta-Steencken, Frank A Middleton, Justin R Siebert, Donna J Osterhout, Dennis J Stelzner
BACKGROUND: The spinal cord is limited in its capacity to repair after damage caused by injury or disease. However, propriospinal (PS) neurons in the spinal cord have demonstrated a propensity for axonal regeneration after spinal cord injury. They can regrow and extend axonal projections to re-establish connections across a spinal lesion. We have previously reported differential reactions of two distinct PS neuronal populations-short thoracic propriospinal (TPS) and long descending propriospinal tract (LDPT) neurons-following a low thoracic (T10 ) spinal cord injury in a rat model...
March 18, 2019: BMC Neuroscience
Daqing Piao, Lara A Sypniewski, Danielle Dugat, Christian Bailey, Daniel J Burba, Luis DeTaboada
The target level photobiomodulation (PBM) irradiances along the thoracic to lumbar segment of the interior spinal canal in six cadaver dogs resulting from surface illumination at 980 nm were measured. Following a lateral hemi-laminectomy, a flexible probe fabricated on a plastic tubular substrate of 6.325 mm diameter incorporating nine miniature photodetectors was embedded in the thoracic to lumbar segment of the spinal canal. Intra-spinal irradiances at the nine photodetector sites, spanning an approximate 8 cm length caudal to T13, were measured for various applied powers of continuous wave (CW) surface illumination at 980 nm with a maximal power of 10 W corresponding to a surface irradiance of 3...
March 16, 2019: Lasers in Medical Science
H Bahadir Gokcen, Cagatay Ozturk
BACKGROUND: Achondroplasia, a genetic disorder of bone growth, produces specific clinical features of the extremities and spine. Spinal stenosis, seen in patients with achondroplasia, is a congenital disorder related to premature fusion of the pedicles to the lamina. It can be caused by ossification of the ligamentum flavum, which is rare in patients with achondroplasia. CASE PRESENTATION: We report a rare congenital spinal stenosis with ossification of the ligamentum flavum and thoracolumbar kyphosis deformity in a 24-year-old man with dwarfism and achondroplasia...
March 12, 2019: World Neurosurgery
Yanbin Zhang, Qifeng Peng, Shengru Wang, Yang Yang, Guanfeng Lin, Jianguo Zhang
OBJECTIVEConcerns remain over the influence of pedicle screw instrumentation on the growth potential of an immature spine. Previous studies have reported discrepancies between animal experiments and clinical studies. The authors' objective was to explore the influence of pedicle screw instrumentation on the growth of an immature spine at a very young age.METHODSIndividuals who met the authors' criteria were included. Anteroposterior diameter of the vertebral body; pedicle length on both sides; and anteroposterior diameter, transverse diameter, and area of the spinal canal were measured on CT images before surgery and at the final follow-up...
March 15, 2019: Journal of Neurosurgery. Pediatrics
Christian Reynolds, Donal S O'Leary, Cheng Ly, Scott A Smith, Zeljka Minic
Autonomic dysreflexia (AD) often occurs in individuals living with spinal cord injury (SCI) and is characterized by uncontrolled hypertension in response to otherwise innocuous stimuli originating below the level of the spinal lesion. Visceral stimulation is a predominate cause of AD in humans, and effectively replicates the phenotype in rodent models of SCI. Direct assessment of sympathetic responses to viscerosensory stimulation in spinalized animals is challenging and requires invasive surgical procedures necessitating the use of anesthesia...
March 15, 2019: American Journal of Physiology. Heart and Circulatory Physiology
G A Korshunova, A E Shul'ga, V V Zaretskov, A A Smol'kin
AIM: To estimate the character of neurophysiological monitoring in patients with thoracic and lumbar spine injuries at different treatment stages. MATERIAL AND METHODS: Thirty-eight patients with non-complicated (22 patients, group 1) and complicated (16 patients, group 2) thoracic and lumbar spine injuries underwent electroneuromyography (ENM) and transcranial magnetic stimulation (TMS). The examination was performed at early (up to 2 weeks) and later (more than 1 month) post-injury periods, before the operation and on the 10th day after decompressing-stabilizing interventions...
2019: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
Qiqi Peng, Yunsheng Ou, Yong Zhu, Zenghui Zhao, Wei Luo, Xing Du, Jianxiao Li
Objective: To explore the feasibility of posterior debridement, decompression, bone grafting, and fixation in treatment of thoracic spinal tuberculosis with myelopathy, and investigate the effects of surgical timing on postoperative outcomes. Methods: The clinical data of 26 patients with thoracic spinal tuberculosis with myelopathy between August 2012 and October 2015 was retrospectively analyzed. All patients underwent posterior unilateral transpedicular debridement, decompression, bone grafting, and fixation and were divided into two groups according to surgical timing...
March 1, 2019: Chinese Journal of Reparative and Reconstructive Surgery
Tao Liu, Shuiqiang Qiu, Zhigang Xu, Jisheng Gu, Qiang Chen, Zhendong Luo, Desheng Wu
Objective: To explore the effect on sagittal spine-pelvis balance of different fusion segments in anterior cervical discectomy and fusion (ACDF). Methods: The clinical data of 326 patients with cervical spondylotic myelopathy, treated by ACDF between January 2010 and December 2016, was retrospectively analysed. There were 175 males and 151 females with an average age of 56 years (range, 34-81 years). Fusion segments included single segment in 69 cases, double segments in 85 cases, three segments in 90 cases, and four segments in 82 cases...
March 1, 2019: Chinese Journal of Reparative and Reconstructive Surgery
Alfred Pokmeng See, Katie Pricola Fehnel, Darren B Orbach, Edward R Smith
The literature has long attempted distinct classifications of arteriovenous fistulae and arteriovenous malformations of the spine.1-3 It is worth noting that lesions can become more complex during recurrence and may not adhere to traditional definitions. In these cases, recognizing the principles of pathology and pathophysiology can guide management and treatment. We present the case of a spinal arteriovenous malformation with recurrence after prior treatment that is managed in the setting of a second opinion with a multidisciplinary approach...
March 15, 2019: Operative Neurosurgery (Hagerstown, Md.)
John Paul G Kolcun, Michael Y Wang
BACKGROUND: Emerging technologies in minimally-invasive spinal surgery include surgical robots for navigation and spinal endoscopy. We applied these technologies in concert to treat a critically ill patient with thoracic discitis. CASE DESCRIPTION: The patient is an 83-year old woman with extensive medical comorbidities. In 2016, she was admitted from her skilled nursing facility with chest pain radiating to her left arm. Following a negative cardiac workup, CT-imaging revealed a right paramediastinal thoracic collection with endplate erosion at the T4 and T5 levels...
March 11, 2019: World Neurosurgery
Isabelle Pagé, Éric Biner, Martin Descarreaux
OBJECTIVE: The purpose of this study was to compare vertebral displacements (absolute and relative) and muscle responses induced by spinal manipulative therapy of short (spinal manipulation) and long (spinal mobilization) impulse duration. METHODS: Twenty-five healthy adults (without thoracic pain) were recruited for this crossover study. Six spinal manipulative therapies (255 N peak force) of different impulse durations (100, 125, 200, 500, 1000, and 1500 ms) were delivered to each participant's T7 transverse process using a mechanical device...
November 2018: Journal of Manipulative and Physiological Therapeutics
Isabelle Pagé, Michael Swain, Arnold Wong, Alexander Breen, Diana De Carvalho, Martin Descarreaux, Martha Funabashi, Gregory Kawchuk
OBJECTIVE: The purpose of this study was to describe the correlations between individual characteristics and spinal stiffness as measured with different spinal stiffness measurement devices in individuals with and without back pain. METHODS: A secondary analysis of 3 adult data sets obtained using 3 different devices, in 2 spinal regions, from a total of 5 separate cross-sectional studies was conducted. Differences in spinal stiffness between men and women and in the strength of correlations among spinal stiffness and age and anthropometric characteristics were evaluated using either the t test for independent samples, Pearson's correlation coefficient, or Kendall's τ rank correlation coefficient...
November 2018: Journal of Manipulative and Physiological Therapeutics
Huan Sheu, Jen-Chung Liao, Yu-Chih Lin
BACKGROUND: Compared to patients without Parkinson's disease (PD), patients with PD who underwent spinal surgeries were reported to have a relatively high complication rate. However, studies that analyze surgical risk factors for these patients are limited. METHODS: From October 2004 to April 2015, patients with PD who underwent spinal surgeries at our department were reviewed. Patients who underwent lumbar or thoracolumbar instrumented surgeries due to degeneration or deformity disease were included...
March 14, 2019: BMC Musculoskeletal Disorders
Diego Serrano-Muñoz, Julio Gómez-Soriano, Elisabeth Bravo-Esteban, Gerardo Ávila-Martín, Iriana Galán-Arriero, Julian Taylor, Juan Avendaño-Coy
The main aim of this work was to investigate the difference in the excitability of the soleus H-reflex in healthy volunteers following spinal transcutaneous electrical nerve stimulation (TENS) and high-frequency alternating current (HFAC) at a frequency of 10 kHz applied at the lower thoracic spinal level (T10-T12). A double-blind, randomized, crossover, controlled clinical trial was designed. Participants received three randomized interventions (TENS, 10 kHz, and sham stimulation) during 40 min. The amplitude and latency of the soleus H-reflex were registered prior to, during, and 10 min following stimulation...
March 7, 2019: Journal of Electromyography and Kinesiology
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