keyword
https://read.qxmd.com/read/39273975/development-and-characterization-of-a-new-tilling-population-for-forward-and-reverse-genetics-in-barley-hordeum-vulgare-l
#1
JOURNAL ARTICLE
Feifei Wang, Liang Zhu, Zhenxiang Zhou, Yangyang Gu, Baojian Guo, Chao Lv, Juan Zhu, Xiaohui Liu, Rugen Xu
Mutagenesis is an important tool in crop improvement and free of the regulatory restrictions imposed on genetically modified organisms. Barley ( Hordeum vulgare L.) is a diploid species with a genome smaller than those of other members of the Triticeae crops, making it an attractive model for genetic studies in Triticeae crops. In this study, we report an ethyl methane sulfonate (EMS)-mutagenized population in the Chinese barley landrace TX9425, which is tolerant to both abiotic and biotic stress. A TILLING (Targeting Induced Locus Lesion in Genomes) population consisting of 2000 M2 lines was also constructed based on the CEL I enzyme with subsequent polyacrylamide electrophoresis, which decreased the cost and labor investment...
September 5, 2024: Plants (Basel, Switzerland)
https://read.qxmd.com/read/39272134/test-preparation-breeds-success-two-quasi-experimental-interventions-in-the-context-of-the-swiss-aptitude-test-for-medical-school-admissions
#2
JOURNAL ARTICLE
Petra L Klumb, Benjamin Spicher
BACKGROUND: In Switzerland, the scholastic aptitude test for medical-school selection takes place in three languages. This study examined the effects of two quasi-experimental interventions that aimed to reduce existing differences in test results between the French- and German-speaking language candidates. METHODS: Between 2018 and 2023, the population of applicants to Swiss medical schools consisted of N = 18'824 German- and French-speaking individuals...
September 13, 2024: BMC Medical Education
https://read.qxmd.com/read/39269329/critical-steps-for-determining-capacity-to-refuse-emergency-medical-services-transport-a-modified-delphi-study
#3
JOURNAL ARTICLE
Eli A Carrillo, Steven P Ignell, Sharon Wulfovich, Michael J Vernon, Stefanie S Sebok-Syer
OBJECTIVES: Emergency physicians without specialized Emergency Medical Services (EMS) training are often required to provide online medical oversight. One common ethical question faced by these physicians is the assessment for decision-making capacity in a patient who does not accept EMS transport to the hospital. We sought expert consensus for a standardized set of guiding questions and recommendations to ensure a rigorous and feasible capacity assessment. METHODS: A modified Delphi method approach was used to achieve group consensus among expert individuals...
September 13, 2024: Prehospital Emergency Care
https://read.qxmd.com/read/39268513/air-temperature-and-humidity-impact-out-of-hospital-cardiac-arrests-in-germany-a-10-year-cohort-study-from-the-german-resuscitation-registry
#4
JOURNAL ARTICLE
Maximilian Burger, Patrick Ristau, Andreas Bohn, Matthias Fischer, Ingvild Beathe Myrhaugen Tjelmeland, Stephan Seewald, Jan-Thorsten Gräsner, Jan Wnent
OBJECTIVES: This study examines the impact of temperature variations on out-of-hospital-cardiac-arrests in Germany over a decade (2010-2019). Out-of-hospital-cardiac-arrests affects 164 per 100,000 inhabitants annually in Germany, 11% survive to hospital discharge. The following study investigates days with the following characteristics: summer days, frost days, and high humidity days. Furthermore, the study explores incidence, causes, demographics, and outcomes of out-of-hospital-cardiac-arrests...
December 2024: Resuscitation plus
https://read.qxmd.com/read/39267170/automatic-external-defibrillator-aed-location-seconds-that-save-lifes
#5
JOURNAL ARTICLE
Wojciech Timler, Filip Jaskiewicz, Joanna Kempa, Dariusz Timler
INTRODUCTION AND OBJECTIVE: Sudden cardiac arrest (SCA) is a significant cause of adult mortality, categorized into in-hospital (IHCA) and out-of-hospital (OHCA). Survival in OHCA depends on early diagnosis, alerting Emergency Medical Service (EMS), high-quality bystander resuscitation, and prompt Automatic External Defibrillator (AED) use. Accelerating technological progress supports faster AED retrieval and use, but there are barriers in real-life OHCA situations. The study assesses 6th-year medical students' ability to locate AEDs using smartphones, revealing challenges and proposing solutions...
September 12, 2024: Archives of Public Health, Archives Belges de Santé Publique
https://read.qxmd.com/read/39267143/augmented-reality-virtual-reality-wartime-training-of-reserve-prehospital-teams-a-pilot-study
#6
JOURNAL ARTICLE
Arielle Kaim, Efrat Milman, Eyal Zehavi, Amnon Harel, Inbal Mazor, Eli Jaffe, Bruria Adini
BACKGROUND: In the realm of trauma response preparation for prehospital teams, the combination of Augmented Reality (AR) and Virtual Reality (VR) with manikin technologies is growing in importance for creating training scenarios that closely mirror potential real-life situations. The pilot study focused on training of airway management and intubation for trauma incidents, based on a Trauma AR-VR simulator involving reserve paramedics of the National EMS service (Magen David Adom) who had not practiced for up to six years, activated during the Israel-Gaza conflict (October 2023)...
September 12, 2024: Israel Journal of Health Policy Research
https://read.qxmd.com/read/39266957/prevalence-predictors-and-outcomes-of-self-reported-feedback-for-ems-professionals-a-mixed-methods-diary-study
#7
JOURNAL ARTICLE
Caitlin Wilson, Luke Budworth, Gillian Janes, Rebecca Lawton, Jonathan Benn
BACKGROUND: Providing feedback to healthcare professionals and organisations on performance or patient outcomes may improve care quality and professional development, particularly in Emergency Medical Services (EMS) where professionals make autonomous, complex decisions and current feedback provision is limited. This study aimed to determine the content and outcomes of feedback in EMS by measuring feedback prevalence, identifying predictors of receiving feedback, categorising feedback outcomes and determining predictors of feedback efficacy...
September 13, 2024: BMC Emergency Medicine
https://read.qxmd.com/read/39264840/consensus-statement-of-the-national-association-of-ems-physicians-international-association-of-fire-chiefs-and-the-international-association-of-chiefs-of-police-best-practices-for-collaboration-between-law-enforcement-and-emergency-medical-services-during-acute
#8
JOURNAL ARTICLE
Michael K Levy, David K Tan, David Q McArdle, Mike McEvoy, Douglas F Kupas, Gerald Beltran, Diane L Miller
Emergency Medical Services (EMS) and law enforcement (LE) frequently work as a team in encounters with individuals experiencing acute behavioral emergencies manifesting with severe agitation and aggression. The optimal management is a rehearsed, coordinated effort by law enforcement and EMS providing the necessary interventions to address behaviors that endanger the patient, the responders, and the public. The purpose of this document is to provide guidance and direction in the shared responsibility of managing and caring for a person displaying behavioral instability with irrational, agitated, and/or violent behavior...
September 12, 2024: Prehospital Emergency Care
https://read.qxmd.com/read/39262666/perceptions-of-a-naloxone-leave-behind-program-among-emergency-medical-services-personnel-in-michigan-usa
#9
JOURNAL ARTICLE
Jason Brian Gibbons, Olivia K Sugarman, Lauren Byrne, Samantha J Harris, Hridika Shah, Eric G Hulsey, Julie Rwan, Esther Mae Rosner, Anthony Pantaleo, Emily Bergquist, Brendan Saloner
INTRODUCTION: In 2020, Michigan implemented its first Naloxone Leave-Behind Program for Emergency Medical Service (EMS) field providers. Under the program, EMS field providers leave naloxone kits to individuals aged 15 or older they encounter in the field who have overdosed, who indicate they have a substance use disorder, or exhibit signs of opioid use and/or to bystanders, friends, or family that are present at the encounter. METHODS: Survey of EMS field providers and administrators to assess perspectives on the Michigan NLB program...
September 2024: Drug Alcohol Depend Rep
https://read.qxmd.com/read/39256650/prehospital-neurological-emergencies-a-survey-on-the-state-of-prehospital-neurological-assessment-by-emergency-medical-professionals
#10
JOURNAL ARTICLE
Vesta Brauckmann, Dominica Ratuszny, Pascal Gräff, Torben Riecke, Gökmen Aktas, Jorge Mayor, Christian Macke
BACKGROUND: Neurological emergencies are one of the major diagnosis groups in the Emergency Medical Services (EMS) with the highest rate of misdiagnosis. Despite the knowledge of time sensitivity and the importance of prehospital factors, prehospital delay is common. Although several stroke triage scales have been developed, a gold standard in the prehospital setting is lacking. OBJECTIVES: Our aim was to evaluate the perception of neurological emergencies by EMS personnel and to identify current problems, difficulties and opportunities for improvement in the prehospital management of stroke, seizure, non-specific neurological symptoms, and paediatric neurological emergencies...
September 11, 2024: BMC Emergency Medicine
https://read.qxmd.com/read/39253959/the-reality-of-rurality-understanding-the-impact-of-remoteness-on-out-of-hospital-cardiac-arrest-in-western-australia-a-retrospective-cohort-study
#11
JOURNAL ARTICLE
Ashlea Smith, Stephen Ball, Karen Stewart, Judith Finn
INTRODUCTION: Western Australia (WA) spans a large, sparsely-populated area of Australia, presenting a challenge for the provision of Emergency Medical Service (EMS), particularly for time-critical emergencies such as out-of-hospital cardiac arrest (OHCA). OBJECTIVE: To assess the impact of rurality on the epidemiology, incidence and survival of OHCA in WA. METHODS: We conducted a retrospective cohort study of EMS-attended OHCA in WA from 2015 to 2022...
September 10, 2024: Australian Journal of Rural Health
https://read.qxmd.com/read/39253576/identification-of-a-recessive-gene-rgm4g52-conferring-red-glume-stem-and-rachis-in-a-triticum-boeoticum-mutant
#12
JOURNAL ARTICLE
Longyu Chen, Junqing Zhang, Pan Ma, Yongping Miao, Lei Wu, Ke Zhou, Jiaru Yang, Minghu Zhang, Xin Liu, Bo Jiang, Ming Hao, Lin Huang, Shunzong Ning, Xuejiao Chen, Xue Chen, Dengcai Liu, Hongshen Wan, Lianquan Zhang
Anthocyanins are plant secondary metabolites belonging to the polyphenol class of natural water-soluble phytopigments. The accumulation of anthocyanins in different plant tissues can improve plant survival under adverse conditions. In addition, plants with the resulting colorful morphology can be utilized as landscape plants. Triticum boeoticum (syn. Triticum monococcum ssp. aegilopoides , 2n=2x=14, Ab Ab ) serves as a valuable genetic resource for the improvement of its close relative common wheat in terms of enhancing resilience to various biotic and abiotic stresses...
2024: Frontiers in Plant Science
https://read.qxmd.com/read/39251658/nutritional-status-and-extended-metabolic-screening-in-egyptian-children-with-uncomplicated-type-1-diabetes
#13
JOURNAL ARTICLE
Hala M Sakhr, Mohammed H Hassan, Ahmed El-Abd Ahmed, Nagwan I Rashwan, Rehab H Abdel-Aziz, Amr S Gouda, Rana Toghan
Nutritional status assessment, including amino acids, carnitine, and acylcarnitine profile, is an important component of diabetes care management, influencing growth and metabolic regulation. A designed case-control research included 100 Egyptian participants (50 T1DM and 50 healthy controls) aged 6 to 18 years old. The participants' nutritional status was assessed using the Body Mass Index (BMI) Z-score. Extended metabolic screening (EMS) was performed using a high-performance liquid chromatography-electrospray ionization-mass spectroscopy system to evaluate the levels of 14 amino acids, free carnitine, and 27 carnitine esters...
September 10, 2024: Scientific Reports
https://read.qxmd.com/read/39250154/initial-defibrillator-pad-position-and-outcomes-for-shockable-out-of-hospital-cardiac-arrest
#14
JOURNAL ARTICLE
Joshua R Lupton, Craig D Newgard, David Dennis, Jack Nuttall, Ritu Sahni, Jonathan Jui, Matthew R Neth, Mohamud R Daya
IMPORTANCE: Ventricular fibrillation (VF) or pulseless ventricular tachycardia (pVT) are the most treatable causes of out-of-hospital cardiac arrest (OHCA). Yet, it remains unknown if defibrillator pad position, placement in the anterior-posterior (AP) or anterior-lateral (AL) locations, impacts patient outcomes in VF or pVT OHCA. OBJECTIVE: To determine the association between initial defibrillator pad placement position and OHCA outcomes for patients presenting with VF or pVT...
September 3, 2024: JAMA Network Open
https://read.qxmd.com/read/39246831/influence-of-patient-body-weight-on-the-probability-of-return-of-spontaneous-circulation-following-out-of-hospital-cardiac-arrest-an-exploratory-analysis
#15
JOURNAL ARTICLE
Michael W Hubble, Ginny R Kaplan, Melisa Martin
INTRODUCTION: In addition to key interventions, including bystander CPR and defibrillation, successful resuscitation of out-of-hospital cardiac arrest (OHCA) is also associated with several patient-level factors, including a shockable presenting rhythm, younger age, Caucasian race and female sex. An additional patient-level factor that may influence outcomes is patient weight, yet this attribute has not been extensively studied within the context of OHCA, despite globally increasing obesity rates...
September 1, 2024: British paramedic journal
https://read.qxmd.com/read/39242729/effectiveness-of-whole-body-electromyostimulation-on-knee-pain-and-physical-function-in-knee-osteoarthritis-a-randomized-controlled-trial
#16
RANDOMIZED CONTROLLED TRIAL
Stephanie Kast, Wolfgang Kemmler, Frank W Roemer, Matthias Kohl, Adam G Culvenor, Ali Mobasheri, Michael Uder, Simon von Stengel
In a randomized, controlled study, whole-body electromyostimulation (WB-EMS) was investigated as a promising alternative treatment technique compared to conventional strength training for the management of knee osteoarthritis (OA). Seventy-two overweight participants with symptomatic knee OA were randomly assigned to WB-EMS (n = 36) or a usual care group (UCG, n = 36). For seven months, the WB-EMS group received three times per fortnight a WB-EMS training, while the UCG was prescribed six-times physiotherapeutic treatments...
September 6, 2024: Scientific Reports
https://read.qxmd.com/read/39241657/aopps-induces-emt-and-fibrosis-by-activating-oxidative-stress-through-erk-p38-mapk-signaling-pathway-in-endometriosis
#17
JOURNAL ARTICLE
Xiaoqing Luo, Sixi Wen, Junling Zeng, Jing Liu, Wenting Ye, Jiangpeng Wu, Songyu Huang, Wuwei Xie, Haiping Wen, Yan Sun, Jing Cai, Daidi Mo, Qianxia Lin, Mingwei Chen, Siyu Xia, Yali Song
Epithelial-mesenchymal transition (EMT) is known to play a crucial role in the development of endometriosis (EMs). However, the exact mechanisms involved in EMT regulation in EMs are not well understood. In this study, we performed comprehensive research using clinical samples, single-cell sequencing, and in vivo/in vitro models to investigate the effects of advanced oxidation protein products (AOPPs) on EMT and the underlying mechanisms in EMs. Combining bioinformatics analysis with experimental validation, our results show that AOPPs accumulate in EMs tissues, and their levels positively correlate with the expression of EMT markers in fibrotic lesions of EMs patients...
September 5, 2024: Reproductive Biology
https://read.qxmd.com/read/39237991/a-timeliness-analysis-of-emergency-services-and-cardiovascular-outcomes-in-cardiac-patients-referred-through-prehospital-emergency-services-between-2020-and-2023-a-cross-sectional-study-in-iran
#18
JOURNAL ARTICLE
Mohammad Soleimanian, Mostafa Bijani, Leila Nikrouz, Mohammad Mehdi Naghizadeh, Kamran Ranjbar, Gholamali Heidari
OBJECTIVE: Effective time management is crucial for the survival of all patients, particularly those with cardiovascular conditions. This is especially true in the context of pre-hospital emergency services, where prompt intervention can significantly impact outcomes. This study delves into the timeliness of emergency services and the subsequent outcomes for hospitalized cardiovascular patients in EMS center in Fasa University of Medical Sciences, southern Iran. RESULTS: A total of 4972 emergency calls related to cardiac diagnoses were received between 2020 and 2023...
September 5, 2024: BMC Research Notes
https://read.qxmd.com/read/39237542/assistance-time-and-peripheral-oxygen-saturation-in-prehospital-emergency-data-as-predictors-of-covid19-hospital-outcomes
#19
JOURNAL ARTICLE
Eduardo Fernandes, Bernardo Maia da Silva, Cássia da Luz Goulart, Jefferson Valente, Anna Gabriela Rezende, João Ricardo Nickening Vissoci, Nádia Cubas, Juliana Magalhães, Camila Sato, Taynna Vernalha, Robson Amorim, Guilherme Tinoco Arêas, Fernando Almeida-Val
To verify if data obtained in the prehospital evaluation of patients with severe acute respiratory syndrome (SARS) during the initial response to the COVID-19 pandemic is associated with clinical outcomes: mechanical ventilation, hospital discharge, and death. This is a retrospective analysis involving secondary data from the Emergency Medical Service (EMS) records and the Health Surveillance Information System of patients assisted by the EMS in Manaus, from January to June 2020, the period of the first peak of COVID-19 cases...
September 6, 2024: Scientific Reports
https://read.qxmd.com/read/39237439/examining-emergency-medical-services-delay-time-response-time-on-scene-time-in-six-peaks-of-the-covid-19-pandemic-in-eastern-iran
#20
JOURNAL ARTICLE
Kheizaran Miri, Mohammadreza Sabbaghi, Mohammad Namazinia
BACKGROUND: Time indices are key elements in prehospital medical emergencies. The number of calls to Emergency Medical Services (EMS) and the number of missions they have undertaken have been impacted by the COVID-19 epidemic. OBJECTIVES: This study's goal was to evaluate prehospital EMS time indices at the apex of the COVID-19 outbreak. METHODS: Data were extracted retrospectively from the Asayar Automation System, which records details on all emergency medical calls resulting in patient transport...
August 10, 2024: Journal of Emergency Medicine
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