Merve Kavak Balgetir, Nalan Kaya Tektemur, Ahmet Tektemur, Gaffari Türk, İbrahim Halil Güngör, Aslıhan Cakir Cihangiroglu, Ramazan Fazıl Akkoç, Tuncay Kuloglu, Durrin Ozlem Dabak
The present study investigates the changes in M1/M2 macrophage polarization resulting from unilateral testicular torsion in the bilateral testis. The study sample included 63 male Sprague-Dawley rats, which were randomly divided into nine groups (n = 7): Control, Sham (4 h (4 h), 24 h, 7 days (7d), 14d), and Torsion/Detorsion (T/D) (4 h, 24 h, 7d, 14d). Histopathological evaluations revealed no changes in the Sham groups, while T/D was noted to cause edema, vascular occlusion, disruption of seminiferous tubule epithelial organization, germ cell abnormalities and structural anomalies in the experimental rats, the severity and extent of which increased from 4 h to 14d after T/D...
March 26, 2024: Reproductive Sciences