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JOURNAL ARTICLE
Risco van Vliet, Lennert Breedveld, Annemieke A J Heutinck, Bram H A Ockeloen, Arnoud W J van ' Hof, Xavier R J Moors
BACKGROUND: Procedural sedation and analgesia (PSA) is a technique of administering sedatives to induce a state that allows the patient to tolerate painful procedures while maintaining cardiorespiratory function, a condition that is frequently desired prehospital. Non-physician prehospital clinicians often have a limited scope of practice when it comes to providing analgesia and sedation; sometimes resulting in a crew request for back-up from physician-staffed prehospital services.". This is also the case if sedation is desirable...
May 1, 2024: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
#42
JOURNAL ARTICLE
Alexandra-Maria Stommel, Harald Herkner, Calvin Lukas Kienbacher, Brigitte Wildner, Alexander Hermann, Thomas Staudinger
PURPOSE: A systematic review and meta-analysis to evaluate the impact of extracorporeal carbon dioxide removal (ECCO2 R) on gas exchange and respiratory settings in critically ill adults with respiratory failure. METHODS: We conducted a comprehensive database search, including observational studies and randomized controlled trials (RCTs) from January 2000 to March 2022, targeting adult ICU patients undergoing ECCO2 R. Primary outcomes were changes in gas exchange and ventilator settings 24 h after ECCO2 R initiation, estimated as mean of differences, or proportions for adverse events (AEs); with subgroup analyses for disease indication and technology...
April 30, 2024: Critical Care: the Official Journal of the Critical Care Forum
#43
JOURNAL ARTICLE
Mary Ichiuji, Laura Asakura, Carol Cain, Nancy Aye, Tatjana Kolevska, David Chen, Farah Mohebpour Brasfield, Dinesh Kotak
BACKGROUND: The rapid evolution, complexity, and specialization of oncology treatment makes it challenging for physicians to provide care based on the latest and best evidence. We hypothesized that physicians would use evidence-based trusted care pathways if they were easy to use and integrated into clinical workflow at the point of care. METHODS: Within a large integrated care delivery system, we assembled clinical experts to define and update drug treatment pathways, encoded them as flowcharts in an online library integrated with the electronic medical record, communicated expectations that clinicians would use these pathways for every eligible patient, and combined data from multiple sources to understand usage over time...
May 1, 2024: BMC Health Services Research
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JOURNAL ARTICLE
Victoria Churchill, Yu-Mei Schoenberger, Vivian L Carter, Jamirah Y Chevrin, Windy Dean-Colomb, Roland Matthews, Desiree Rivers, Stephen O Sodeke, Jonathan Ezer, Brian M Rivers
Research advances on effective methods to prevent, diagnose, and treat cancer continue to emerge through clinical and genomic research. Most clinical trial and genomic research participants identify as White which limits the generalizability of research findings to non-White populations. With the development and access to technology, digital delivery of salient and tailored health education may provide innovative pathways to increase representation of African Americans (AA) and Hispanics in research. This project focused on the creation of a bioethical sensitive education video aimed at increasing participation in clinical trials and genomic research by bringing together experts from the community, healthcare, biomedical research, and public health...
May 2, 2024: Journal of Cancer Education: the Official Journal of the American Association for Cancer Education
#45
JOURNAL ARTICLE
Satoshi Takanashi, Yuko Kaneko, Yutaka Kawahito, Takashi Kida, Takahiko Sugihara, Toshihisa Kojima, Ryozo Harada, Michinori Ishitoku, Shintaro Hirata, Motomu Hashimoto, Toshihiko Hidaka, Asami Abe, Hajime Ishikawa, Hiromu Ito, Mitsumasa Kishimoto, Kazuo Matsui, Toshihiro Matsui, Isao Matsushita, Akira Onishi, Akio Morinobu, Keiichiro Nishida, Shuji Asai, Eiichi Tanaka, Masayoshi Harigai, Masayo Kojima
Objectives We investigated the current perspectives regarding the management of late-onset rheumatoid arthritis (LORA) among rheumatologists in clinical practice. Methods This study was performed in October 2021, and included 65 rheumatologists certified by the Japan College of Rheumatology, who were administered questionnaires (including multiple choice and descriptive formulae) regarding the management of LORA. We aggregated and analyzed the responses. Results All 65 rheumatologists responded to the survey; 47 (72%) answered that >50% of newly diagnosed patients were aged ≥65 years, 42 (65%) answered that achievement of remission or low disease activity was the treatment goal, and 40 (62%) considered patient safety to be the highest priority...
May 2, 2024: Internal Medicine
#46
JOURNAL ARTICLE
Rina Di Bonaventura, Lara Brunasso, Carmelo Lucio Sturiale, Iacopo Valente, Alessandro Pedicelli, Enrico Marchese, Rosario Maugeri, Domenico Gerardo Iacopino, Alessandro Olivi, Alessio Albanese
BACKGROUND: Interruption of the fistoulus point is the goal of the treatment of spinal dural arteriovenous fistula (dAVFs). Microsurgery still represents a highly efficient treatment in terms of complete occlusion with the lowest risk of recurrence rate. It is reported that the hardest step consists in finding the fistulous site itself, potentially extending surgical access and time, and increasing potential post-operative surgical-related complications. The accurate preoperative detection of the shunt and spinal level together is crucial for guiding optimal, fast and safe microsurgical treatment...
April 29, 2024: World Neurosurgery
#47
Shindo Isack Kilawa, Gilbert Zacharia Nkya, Reginald R Shoo, Peter Magembe Mrimba, Rogers J Temu, Octavian A Shirima
INTRODUCTION AND IMPORTANCE: Megadactyly of the foot is uncommon non hereditary congenital anomalies of the extremities and poses a dilemma on treatment however multiple treatment modalities were developed but is not uniform to all patients with megadactyly. The goal of the surgical treatment is to achieve painless and function of the foot. CASE PRESENTATION: We report a 14 years old male presented with complaints of progressive enlargement 2nd, 3rd, 4th and 5th toes of the right foot since birth, associated with inability to wear shoes...
April 30, 2024: International Journal of Surgery Case Reports
#48
JOURNAL ARTICLE
Yoshihiro Sowa, Ataru Sunaga, Yuya Morishita, Shino Higai, Yoshihiro Toyohara, Kotaro Yoshimura
BACKGROUND: A congenital constriction band (CCB) is a relatively common anomaly among limb malformations. However, the number of cases treated at a given center is limited and differences in techniques used by surgeons at each facility have a significant impact on the treatment outcomes. Several surgical methods have been reported, but a standard technique that yields consistent satisfactory results is still needed. Here, we introduce a novel technique for the treatment of CCB syndrome that uses a combination of wave-like skin incision and Z-axis Z-plasty...
April 16, 2024: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
#49
REVIEW
Mohammadtaghi Vakili, Giovanni Cagnetta, Shubo Deng, Wei Wang, Zahra Gholami, Fatemeh Gholami, Wafa Dastyar, Amin Mojiri, Lee Blaney
The adsorption process efficiently removes per- and polyfluoroalkyl substances (PFAS) from water, but managing exhausted adsorbents presents notable environmental and economic challenges. Conventional disposal methods, such as incineration, may reintroduce PFAS into the environment. Therefore, advanced regeneration techniques are imperative to prevent leaching during disposal and enhance sustainability and cost-effectiveness. This review critically evaluates thermal and chemical regeneration approaches for PFAS-laden adsorbents, elucidating their operational mechanisms, the influence of water quality parameters, and their inherent advantages and limitations...
April 27, 2024: Journal of Hazardous Materials
#50
JOURNAL ARTICLE
Yafei Li, Lu Yao, Jingyi Yang, Jianhui Wu, Xiao Tang, Shengwen Liang, Yufen Zhang, Yinchang Feng
After the resumption of work and production following the COVID-19 pandemic, many cities entered a "transition phase", characterized by the gradual recovery of emission levels from various sources. Although the overall PM2.5 emission trends have recovered, the specific changes in different sources of PM2.5 remain unclear. Here, we investigated the changes in source contributions and the evolution pattern of pollution episodes (PE) in Wuhan during the "transition period" and compared them with the same period during the COVID-19 lockdown...
April 30, 2024: Ecotoxicology and Environmental Safety
#51
JOURNAL ARTICLE
Jerris L Raiford, Yunfeng Tie, Xin A Yuan, Kathy K Byrd, Kate A Buchacz, Linda Beer
Data from the CDC's Medical Monitoring Project indicate that the United States is on track to meet one of five National HIV/AIDS Strategy (NHAS) Quality of Life goals among cisgender Black women, specifically, hunger/food insecurity. Substantial work needs to be done to improve self-rated health and to decrease unmet need for mental health services. Enhanced and coordinated action are necessary to reach all Quality of Life goals in this NHAS priority population.
June 1, 2024: AIDS
#52
JOURNAL ARTICLE
Ravi Goyal, John Hotchkiss, Boyd Gilman, Pamela W Klein, Robert J Mills, Jennifer Starling, Natasha K Martin, Thomas Patton, Stacy M Cohen, Laura Cheever
OBJECTIVE: Investigate the role of the Ryan White HIV/AIDS Program (RWHAP) - which funds services for vulnerable and historically disadvantaged populations with HIV - in reducing health inequities among people with HIV over a 10-year horizon. DESIGN: We use an agent-based microsimulation model to incorporate the complexity of the program and long-time horizon. METHODS: We use a composite measure (the Theil index) to evaluate the health equity implications of the RWHAP for each of four subgroups (based on race and ethnicity, age, gender, and HIV transmission category) and two outcomes (probability of being in care and treatment and probability of being virally suppressed)...
June 1, 2024: AIDS
#53
JOURNAL ARTICLE
Angela C Bersch-Ferreira, Rachel H V Machado, Júlia S de Oliveira, Renato H N Santos, Lucas R da Silva, Luis G S Mota, Raira Pagano, Erica R R Sady, Débora H K Miyada, Nanci Valeis, Pedro N Martins, Jussara C de Almeida, Dirce M L Marchioni, Enilda M S Lara, Edilaine C S Gherardi-Donato, Driele Quinhoneiro, Ana Paula P F Carvalho, Malaine M A Machado, Lana P F Gedda, Camila M B Ferro, Ana Clara M S Carvalho, Ana Maria P Feoli, Marthina S Walker, Sônia L Pinto, Kellen C Silva, Neide M Bruscato, Emilio H Moriguchi, Andreza M Penafort, Rafaelle A Santiago, Denise R D Osório, Helena B Rower, Marina R Barbosa, Joao Gabriel S T da Silva, Bernardete Weber, Alexandre B Cavalcanti, Aline Marcadenti
OBJECTIVE: To evaluate the effectiveness of a nutritional strategy based on two components and adapted for the public health system on blood pressure, cardiometabolic features, self-care, qualify of life and diet quality in individuals with hypertension. METHODS: NUPRESS was an open-label, parallel-group, superiority randomized controlled clinical trial in which participants at least 21 years with hypertension and poorly controlled blood pressure were randomly assigned (1 : 1 allocation ratio) to either an individualized dietary prescription according to nutritional guidelines (control group, n = 205); or a two-component nutrition strategy, including a goal-directed nutritional counseling and mindfulness techniques (NUPRESS [intervention] group, n = 205)...
February 26, 2024: Journal of Hypertension
#54
JOURNAL ARTICLE
E Gómez, J L Montero, E Molina, L García-Buey, M Casado, J Fuentes, M A Simón, A Díaz-González, F Jorquera, R M Morillas, J Presa, M Berenguer, M I Conde, A Olveira, G Macedo, I Garrido, M Hernández-Guerra, I Olivas, S Rodríguez-Taje, M Londoño, J M Sousa, J Ampuero, E Romero-González, Sh González-Padilla, D Escudero-García, A Carvalho, A Santos, M L Gutiérrez, E Pérez-Fernández, L Aburruza, J Uriz, D Gomes, L Santos, J Martínez-González, A Albillos, C M Fernández-Rodríguez
BACKGROUND: Suboptimal response to ursodeoxycholic acid occurs in 40% of primary biliary cholangitis (PBC) patients, affecting survival. Achieving a deep response (normalisation of alkaline phosphatase [ALP] and bilirubin ≤0.6 upper limit of normal) improves survival. Yet, the long-term effectiveness of second-line treatments remains uncertain. AIMS: To evaluate the long-term effectiveness of obeticholic acid (OCA) ± fibrates. Focusing on biochemical response (ALP ≤1...
May 1, 2024: Alimentary Pharmacology & Therapeutics
#55
REVIEW
Ta-Wei Tai, Hsuan-Yu Chen, Chien-An Shih, Chun-Feng Huang, Eugene McCloskey, Joon-Kiong Lee, Swan Sim Yeap, Ching-Lung Cheung, Natthinee Charatcharoenwitthaya, Unnop Jaisamrarn, Vilai Kuptniratsaikul, Rong-Sen Yang, Sung-Yen Lin, Akira Taguchi, Satoshi Mori, Julie Li-Yu, Seng Bin Ang, Ding-Cheng Chan, Wai Sin Chan, Hou Ng, Jung-Fu Chen, Shih-Te Tu, Hai-Hua Chuang, Yin-Fan Chang, Fang-Ping Chen, Keh-Sung Tsai, Peter R Ebeling, Fernando Marin, Francisco Javier Nistal Rodríguez, Huipeng Shi, Kyu Ri Hwang, Kwang-Kyoun Kim, Yoon-Sok Chung, Ian R Reid, Manju Chandran, Serge Ferrari, E Michael Lewiecki, Fen Lee Hew, Lan T Ho-Pham, Tuan Van Nguyen, Van Hy Nguyen, Sarath Lekamwasam, Dipendra Pandey, Sanjay Bhadada, Chung-Hwan Chen, Jawl-Shan Hwang, Chih-Hsing Wu
OBJECTIVES: This study aimed to present the Asia-Pacific consensus on long-term and sequential therapy for osteoporosis, offering evidence-based recommendations for the effective management of this chronic condition. The primary focus is on achieving optimal fracture prevention through a comprehensive, individualized approach. METHODS: A panel of experts convened to develop consensus statements by synthesizing the current literature and leveraging clinical expertise...
March 2024: Osteoporosis and Sarcopenia
#56
JOURNAL ARTICLE
Sergiu Chirila, Tony Hangan, Leonard Gurgas, Monica Georgiana Costache, Marinela Anisoara Vlad, Bogdan-Florentin Nitu, Sara Melek Bittar, Aurora Craciun, Laura Condur, Geir Bjørklund
BACKGROUND: This study explores patient acceptance of influenza vaccination administered by pharmacists in Romania during the 2023 season, considering it a novel strategy to address gaps in knowledge. Pharmacy-based vaccination deviates from traditional methods, providing high-risk patients with full reimbursement and others with 50% reimbursement, allowing a choice between family doctors and pharmacies for vaccine administration. MATERIAL AND METHOD: The survey includes 15 questions covering socio-demographic data, health information, vaccination preferences, and perceptions of pharmacy-based vaccinations...
2024: Risk Management and Healthcare Policy
#57
JOURNAL ARTICLE
Baolin Zhang, Kanghao Chen, Haodong Yuan, Zhiheng Liao, Taifeng Zhou, Weiming Guo, Shen Zhao, Ruixuan Wang, Peiqiang Su
PURPOSE: The Lenke classification system is widely utilized as the preoperative evaluation protocol for adolescent idiopathic scoliosis (AIS). However, manual measurement is susceptible to observer-induced variability, which consequently impacts the evaluation of progression. The goal of this investigation was to develop an automated Lenke classification system utilizing innovative deep learning algorithms. METHODS: Using the database from the First Affiliated Hospital of Sun Yat-sen University, the whole spinal x-rays images were retrospectively collected...
June 2024: JOR Spine
#58
REVIEW
Somrudee Arunjit, Karnsunaphat Balthip, Jos M Latour
BACKGROUND: The purpose in life can motivate individuals to realize that life is essential for existence and well-being. Adults might experience crises that can lead to a lack of purpose in life. Consequently, promoting purpose in life is necessary, but it requires a suitable measurement scale. OBJECTIVE: This scoping review aimed to identify and map the content, psychometric properties, and answer option scales of instruments intended to measure purpose in life in adult populations...
2024: Belitung nursing journal
#59
JOURNAL ARTICLE
Majida Mramel, Mustafa El Alaoui, Rachid El Janati Idrissi
BACKGROUND: In Morocco, despite various initiatives to improve the quality of reproductive healthcare, the indicators remain unfavorable. To strengthen the skills of midwives and support the achievement of Millennium Development Goals (MDGs) 4 and 5 by 2030, Morocco has developed and implemented a competency-based training framework. However, there is a lack of information on the successful implementation of this program and its impact on the quality of student midwives' preparation for practice...
2024: Belitung nursing journal
#60
JOURNAL ARTICLE
Bengt Herweg, Ritesh S Patel, Sami Noujaim, Joseph Spano, Nicholas Mencer, Pugazhendhi Vijayaraman
BACKGROUND: Cardioneuroablation (CNA) targeting ganglionated plexi has shown promise in treating vasovagal syncope. Only radiofrequency ablation has been used to achieve this goal thus far. OBJECTIVE: The purpose of this study was to investigate the utility of cryoballoon ablation (CBA) of the pulmonary veins (PVs) as a potential simplified approach to CNA. METHODS: We report our observations of autonomic modulation in a series of 17 patients undergoing CBA for atrial fibrillation and our early experience using CBA of the PVs in 3 patients with malignant vagal syncope...
April 2024: Heart rhythm O2
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