keyword
https://read.qxmd.com/read/33135083/sars-cov-2-igg-igm-rapid-test-as-a-diagnostic-tool-in-hospitalized-patients-and-healthcare-workers-at-a-large-teaching-hospital-in-northern-italy-during-the-2020-covid-19-pandemic
#21
JOURNAL ARTICLE
Diana Canetti, Raffaele Dell'Acqua, Niccolò Riccardi, Liviana Della Torre, Alba Bigoloni, Camilla Muccini, Elena Bruzzesi, Martina Ranzenigo, Matteo Chiurlo, Sara Racca, Cristina Galli, Antonella Castagna, Giuseppe Tambussi, Adriano Lazzarin
We describe the outcome of a Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) IgG/IgM rapid test, and discuss the potential suitability of antibody testing. Retrospective single cohort study on patients with suspected Coronavirus Disease 2019 (COVID-19) and asymptomatic Healthcare Workers, enrolled from March to April 2020. Subjects had quantitative PCR (qPCR) test for detection of SARS-CoV-2 via nasal swab and serological testing using the COVID-19 IgG/ IgM Rapid Test (PRIMA Lab SA) immunochromatographic assay...
October 2020: New Microbiologica
https://read.qxmd.com/read/33134936/impact-of-fellows-as-teachers-workshops-on-teaching-rounds-an-observational-study-in-an-icu
#22
JOURNAL ARTICLE
Paul A Bergl, Rose M Franco, Jayshil J Patel, Marium Khan, Kathlyn E Fletcher, Rahul S Nanchal
During training, fellows serve as teachers and role models for junior colleagues. Fellows-as-teachers curricula may support these roles, but little is known about their effectiveness and durability. We sought to measure the long-term effects on ICU rounds after administering fellows-as-teachers workshops. DESIGN: Prospective pre-/postintervention observational study of ICU rounds. SETTING: Tertiary-care medical ICU with both pulmonary critical care and critical care medicine fellowships...
October 2020: Critical care explorations
https://read.qxmd.com/read/33134548/impact-of-covid-19-on-canadian-medical-education-pre-clerkship-and-clerkship-students-affected-differently
#23
JOURNAL ARTICLE
Jobanpreet Dhillon, Ali Salimi, Hassan ElHawary
The coronavirus pandemic (COVID-19) has altered the undergraduate learning experience for many students across Canada. Medical education is no exception; clinical programs, in-person lectures, and mandatory hands-on activities have been suspended to adhere to social distancing guidelines. As remote teaching becomes the forefront of education, medical curricula have been forced to adapt accordingly in order to fulfill the core competencies of medical training and to provide quality education to medical students...
January 2020: Journal of Medical Education and Curricular Development
https://read.qxmd.com/read/33134417/treating-covid-19-with-hydroxychloroquine-teach-a-multicenter-double-blind-randomized-controlled-trial-in-hospitalized-patients
#24
JOURNAL ARTICLE
Robert J Ulrich, Andrea B Troxel, Ellie Carmody, Jaishvi Eapen, Martin Bäcker, Jack A DeHovitz, Prithiv J Prasad, Yi Li, Camila Delgado, Morris Jrada, Gabriel A Robbins, Brooklyn Henderson, Alexander Hrycko, Dinuli Delpachitra, Vanessa Raabe, Jonathan S Austrian, Yanina Dubrovskaya, Mark J Mulligan
Background: Effective therapies to combat coronavirus 2019 (COVID-19) are urgently needed. Hydroxychloroquine (HCQ) has in vitro antiviral activity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), but the clinical benefit of HCQ in treating COVID-19 is unclear. Randomized controlled trials are needed to determine the safety and efficacy of HCQ for the treatment of hospitalized patients with COVID-19. Methods: We conducted a multicenter, double-blind randomized clinical trial of HCQ among patients hospitalized with laboratory-confirmed COVID-19...
October 2020: Open Forum Infectious Diseases
https://read.qxmd.com/read/33134202/impact-of-covid-19-on-medical-students-in-the-united-kingdom
#25
JOURNAL ARTICLE
Sophie Rainbow, Tenzin Dorji
Medical student training in the United Kingdom has undoubtedly been impacted by the COVID-19 pandemic. Most notably, there have been disruptions to teaching, cancellation of exams and clinical electives and the abandonment of research projects. In response, medical education has been reshaped to facilitate the continuation of studies, such as the online deliverance of course material, digital examinations and implementing welfare and financial support systems. There has also been a surge in student volunteers, often playing critical roles in primary and secondary care to support National Health Service (NHS) staff working on the frontlines...
September 2020: Germs
https://read.qxmd.com/read/33133324/ndm-1-positive-k-pneumoniae-at-a-teaching-hospital-in-southwestern-china-clinical-characteristics-antimicrobial-resistance-molecular-characterization-biofilm-assay-and-virulence
#26
JOURNAL ARTICLE
Kai Yang, Shumin Liu, Huanqin Li, Na Du, Jing Yao, Qiuyue He, Yan Du
Background: The emergence of the NDM-1-positive Klebsiella pneumoniae ( K. pneumoniae ) strains has led to limited therapeutic options for clinical treatment. Understanding the clinical characteristics, antimicrobial resistance, biofilm assay, and the virulence genes of these isolated strains is of great significance. Methods: The polymerase chain reaction (PCR) was used to screen isolated NDM-1-positive K. pneumoniae . The clinical information of the patients was collected from medical records...
2020: Canadian Journal of Infectious Diseases & Medical Microbiology
https://read.qxmd.com/read/33133064/induction-of-antigen-specific-tolerance-in-t-cell-mediated-diseases
#27
REVIEW
Laura Passerini, Silvia Gregori
The development of novel approaches to control unwanted immune responses represents an ambitious goal in the management of a number of clinical conditions, including autoimmunity, autoinflammatory diseases, allergies and replacement therapies, in which the T cell response to self or non-harmful antigens threatens the physiological function of tissues and organs. Current treatments for these conditions rely on the use of non-specific immunosuppressive agents and supportive therapies, which may efficiently dampen inflammation and compensate for organ dysfunction, but they require lifelong treatments not devoid of side effects...
2020: Frontiers in Immunology
https://read.qxmd.com/read/33132053/predictors-of-anticoagulation-use-in-indigenous-and-non-indigenous-australians-with-atrial-fibrillation
#28
JOURNAL ARTICLE
Simon Rocheleau, Celine Gallagher, Bradley M Pitman, Samuel J Tu, Nicole Hanna-Rivero, Nicholas Clarke, Dominik Linz, Jeroen M Hendriks, Melissa E Middeldorp, Rajiv Mahajan, Dennis H Lau, Kurt C Roberts-Thomson, Prashanthan Sanders, Christopher X Wong
OBJECTIVE: Prior studies have demonstrated that anticoagulation underutilisation for atrial fibrillation (AF) and elevated stroke risk is common. However, there is little data on factors associated with appropriate anticoagulation, particularly in Indigenous Australians who face a disproportionate burden of AF and stroke. We thus sought to determine factors associated with anticoagulation use in Australians with AF. DESIGN: Administrative, clinical, prescriptive and laboratory data were linked and aggregated over a 12-year period...
May 2021: Heart, Lung & Circulation
https://read.qxmd.com/read/33131364/satisfaction-and-needs-of-pharmacists-in-prescription-checking-training-a-cross-sectional-survey
#29
JOURNAL ARTICLE
Wei Cheng, Chen Wang, Jing Ma, Wen Ji, Xiangli Yang, Bei Wu, Ruigang Hou
OBJECTIVE: Prescription checking is becoming increasingly prevalent in medical institutions. However, the prescription-checking ability of pharmacists requires improvement. The study aim was to explore the main aspects of prescription-checking training and provide an empirical reference for the training of pharmacists in medical institutions. METHODS: Participants were pharmacists willing to complete a Likert questionnaire. Descriptive statistics were used to examine percentages and composition ratios...
November 2020: Journal of International Medical Research
https://read.qxmd.com/read/33130446/nursing-graduates-lived-experiences-of-anxiety-during-their-final-year-at-university-a-phenomenological-study
#30
JOURNAL ARTICLE
Fan-Ko Sun, Ann Long D Phil, Chun-Ying Chiang, Ching-Ju Yang, Chu-Yun Lu
BACKGROUND: Nursing students voiced that they were stressed or anxious during their final year at university. Further, they articulated that their anxiety affected their academic performance as well as their motivation to work on their clinical placement. OBJECTIVES: This study was designed to describe nursing graduates' perceptions of their lived experiences of anxiety during their final year. DESIGN: Phenomenology was chosen. SETTINGS: Three universities in Taiwan...
October 20, 2020: Nurse Education Today
https://read.qxmd.com/read/33130204/diagnosis-and-treatment-of-urinary-tract-infections-in-hospitalized-adults-in-ghana-the-role-of-the-clinical-microbiology-laboratory-in-improving-antimicrobial-stewardship
#31
JOURNAL ARTICLE
Ernestina Gambrah, Alex Owusu-Ofori, Eno Biney, Chris Oppong, Susan E Coffin
BACKGROUND: Inappropriate antibiotics use is a global threat. Clinical microbiology laboratory testing can support optimal antibiotic prescribing for many conditions. The purpose of this study was to characterize antibiotic usage in the context of treatment of uncomplicated urinary tract infection (UTI) received through a Ghanaian Accident & Emergency, which found high rates of improper usage. METHODS: A prospective cohort study recruited patients ≥18 years of age who were admitted to a large Ghanaian teaching hospital with suspected UTI...
October 29, 2020: International Journal of Infectious Diseases: IJID
https://read.qxmd.com/read/33129868/multiparametric-magnetic-resonance-imaging-should-be-preferred-over-digital-rectal-examination-for-prostate-cancer-local-staging-and-disease-risk-classification
#32
COMPARATIVE STUDY
Timo F W Soeterik, Harm H E van Melick, Lea M Dijksman, Douwe H Biesma, J Alfred Witjes, Jean-Paul A van Basten
OBJECTIVE: To assess the impact of multiparametric magnetic resonance imaging (mp-MRI) local tumor staging on prostate cancer risk stratification and choice of treatment. MATERIALS AND METHODS: Prostate cancer patients, newly diagnosed from 2017 to 2018 at 7 Dutch teaching hospitals were included. Risk group classification was done twice, using either digital rectal examination (DRE) or mp-MRI information. Risk group migration and rates of treatment intensification associated with mp-MRI upstaging were established...
January 2021: Urology
https://read.qxmd.com/read/33129196/educating-for-practice-a-new-redesigned-pedagogical-model-of-clinical-forensic-medicine
#33
JOURNAL ARTICLE
Yadong Guo, Zijia Cheng, Yanjun Ding, Jifeng Cai
Nowadays, cultivating experts in clinical forensic medicine (CFM) has become a universal problem worldwide. In most English-speaking countries, CFM is traditionally designed as an introduction and incorporation into medical undergraduate training whereas in China it is an essential sub-specialty of forensic science. The scope, missions, and tasks of this discipline vary widely by virtue of the diversity of countries and legal environment, leading to the difference in pedagogical model, even in professional qualities and abilities...
October 3, 2020: Journal of Forensic and Legal Medicine
https://read.qxmd.com/read/33128192/canada-follows-the-us-in-the-rise-of-bilateral-mastectomies-for-unilateral-breast-cancer-a-23-year-population-cohort-study
#34
JOURNAL ARTICLE
L Findlay-Shirras, I Lima, G Smith, M Clemons, A Arnaout
INTRODUCTION: The use of contralateral prophylactic mastectomy (CPM) continues to grow despite the absence of evidence supporting a survival benefit. This study's objectives were to (1) describe the trends in the rates of unilateral and bilateral mastectomy (BM) in women diagnosed with unilateral breast cancer (UBC) in Ontario, Canada from 1991 to 2013, and (2) identify factors associated with BM to treat UBC. METHODS: This retrospective cohort analysis included all women aged 18 and older diagnosed with UBC between January 1991 and December 2013...
October 30, 2020: Breast Cancer Research and Treatment
https://read.qxmd.com/read/33125607/remote-operation-for-non-fluoroscopic-navigation-of-complex-tachycardias
#35
JOURNAL ARTICLE
Ignacio García-Bolao, David Moñino, Roger Marsal, Pablo Ramos, Ane Erkiaga, Joana Irezabal, Ramón Albarrán-Rincón
PURPOSE: Remote system operation technology was developed and applied to a non-fluoroscopic navigation system in order to overcome Spanish mobility restrictions caused by Covid-19 pandemic infection and subsequently used routinely. METHODS AND RESULTS: Fifty consecutive complex ablations were performed in different days using this technology. All these procedures were assisted remotely with the only intervention of a field clinical specialist located at his home who took full control of the navigation system (keyboard, mouse, and screen) and had bidirectional real-time audio/video feedback with the operating physician...
November 2021: Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing
https://read.qxmd.com/read/33123626/delivering-a-work-integrated-learning-postgraduate-course-during-covid-19-experiences-challenges-and-strategies
#36
JOURNAL ARTICLE
Sarah J Prior, Phoebe Griffin, Lauri O'Brien, Pieter J Van Dam
COVID-19 has had a significant impact on teaching and learning in postgraduate education. In particular, work integrated learning, in health care settings, has been disrupted in many ways negatively impacting student learning. Our Clinical Redesign courses are designed to deliver work-integrated learning in partnership with healthcare organisations to deliver workplace projects in real time, which has been complicated by COVID-19. This reflection examines the challenges that arose in the healthcare redesign teaching and learning space during the COVID-19 pandemic...
January 2020: Journal of Medical Education and Curricular Development
https://read.qxmd.com/read/33123198/rethinking-assessment-concepts-in-dental-education
#37
REVIEW
Mohamed El-Kishawi, Khaled Khalaf, Dana Al-Najjar, Zahra Seraj, Sausan Al Kawas
Introduction: Dental education involves teaching and assessing the acquisition of verifiable domains that require superior psychomotor, communication, and cognitive skills. Evolving technologies and methods of assessment could enhance student's learning environment and improve tutor assessment experience. The aim of this study was to review the current body of research and evaluate the effectiveness of various methods of assessments in improving learning and performance in preclinical and clinical dental practice...
2020: International Journal of Dentistry
https://read.qxmd.com/read/33122958/clinical-practice-competence-of-mettu-university-nursing-students-a-cross-sectional-study
#38
JOURNAL ARTICLE
Bonsa Amsalu, Tadele Fekadu, Ayelign Mengesha, Ebissa Bayana
Introduction: Clinical practice competence is the ability to effectively integrate cognitive, affective and psychomotor skills during the delivery of health care. It is the concern and the center of attention for the managers, professional associations, government, and society as a whole. Therefore, identifying the level of clinical practice competence of students and taking appropriate action is crucial. The aim of the present study was to investigate clinical practice competence of nursing students in Mettu University...
2020: Advances in Medical Education and Practice
https://read.qxmd.com/read/33122929/triglyceride-to-high-density-lipoprotein-cholesterol-ratio-is-an-important-determinant-of-cardiovascular-risk-and-poor-prognosis-in-coronavirus-disease-19-a-retrospective-case-series-study
#39
JOURNAL ARTICLE
Benping Zhang, Chen Dong, Shengzhong Li, Xiaoqing Song, Wang Wei, Li Liu
Background: Acute myocardial injury and heart failure characterized by elevated cardiac troponin and decreased heart pump function are significant clinical features and prognostic factors of coronavirus disease-19 (COVID-19). Triglyceride to high-density lipoprotein cholesterol (TG/HDL-C) ratio is an indicator of insulin resistance. This study aimed to explore the association of the TG/HDL-C ratio with cardiovascular risk and prognosis in COVID-19. Methods: Ninety-eight laboratory-confirmed patients with COVID-19 admitted in a tertiary teaching hospital in Wuhan, China, were enrolled in this retrospective study...
2020: Diabetes, Metabolic Syndrome and Obesity
https://read.qxmd.com/read/33122182/reliability-analysis-of-deep-learning-algorithms-for-reporting-of-routine-lumbar-mri-scans
#40
JOURNAL ARTICLE
Kai-Uwe Lewandrowski, Narendran Muraleedharan, Steven Allen Eddy, Vikram Sobti, Brian D Reece, Jorge Felipe Ramírez León, Sandeep Shah
BACKGROUND: Artificial intelligence could provide more accurate magnetic resonance imaging (MRI) predictors of successful clinical outcomes in targeted spine care. OBJECTIVE: To analyze the level of agreement between lumbar MRI reports created by a deep learning neural network (RadBot) and the radiologists' MRI reading. METHODS: The compressive pathology definitions were extracted from the radiologist lumbar MRI reports from 65 patients with a total of 383 levels for the central canal: (0) no disc bulge/protrusion/canal stenosis, (1) disc bulge without canal stenosis, (2) disc bulge resulting in canal stenosis, and (3) disc herniation/protrusion/extrusion resulting in canal stenosis...
October 29, 2020: International Journal of Spine Surgery
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