Pelin Kardaş Karacaoglu, Suheyl Asma, Aslı Korur, Soner Solmaz, Nurhilal Turgut Buyukkurt, Cigdem Gereklioglu, Mutlu Kasar, Demircan Ozbalcı, Selma Unal, Hasan Kaya, Emel Gurkan, Mahmut Yeral, Çagla Sariturk, Can Boga, Hakan Ozdogu
Sickle cell disease (SCD), one of the most common genetic disorders worldwide, is characterized by hemolytic anemia and tissue damage from the rigid red blood cells. Although hydroxyurea and transfusion therapy are administered to treat the accompanying tissue injury, whether either one prolongs the lifespan of patients with SCD is unknown. SCD-related mortality data are available, but there are few studies on mortality-related factors based on evaluations of surviving patients. In addition, ethnic variability in patient registries has complicated detailed analyses...
May 2016: Annals of Hematology