keyword
https://read.qxmd.com/read/38802461/a-novel-indicator-in-epidemic-monitoring-through-a-case-study-of-ebola-in-west-africa-2014-2016
#21
JOURNAL ARTICLE
Minkyu Kwak, Xiuxiu Sun, Yunju Wi, Kyeongah Nah, Yongkuk Kim, Hongsung Jin
The E/S (exposed/susceptible) ratio is analyzed in the SEIR model. The ratio plays a key role in understanding epidemic dynamics during the 2014-2016 Ebola outbreak in Sierra Leone and Guinea. The maximum value of the ratio occurs immediately before or after the time-dependent reproduction number (Rt ) equals 1, depending on the initial susceptible population (S(0)). It is demonstrated that transmission rate curves corresponding to various incubation periods intersect at a single point referred to as the Cross Point (CP)...
May 27, 2024: Scientific Reports
https://read.qxmd.com/read/38801979/influence-of-marital-status-on-stage-at-presentation-and-disease-specific-survival-in-sebaceous-carcinoma-an-analysis-of-the-surveillance-epidemiology-and-end-results-database
#22
JOURNAL ARTICLE
Mitchell A Taylor, Sierra Thomas, Megan Wackel, Divya Sharma, Erin X Wei
No abstract text is available yet for this article.
May 25, 2024: Journal of the American Academy of Dermatology
https://read.qxmd.com/read/38801652/ebola-virus-specific-neutralizing-antibody-persists-at-high-levels-in-survivors-2-years-after-resolution-of-disease-in-a-sierra-leonean-cohort
#23
JOURNAL ARTICLE
Nell G Bond, Kayla R Shore, Emily J Engel, Erin E Coonan, Foday Al-Hasan, Michael A Gbakie, Fatima K Kamara, Lansana Kanneh, Mambu Momoh, Ibrahim M Kanneh, John D Sandi, Debra Elliott, Samuel C Ficenec, Ashley R Smira, William A Fischer, David A Wohl, James E Robinson, Jeffrey G Shaffer, Robert F Garry, Robert J Samuels, Donald S Grant, John S Schieffelin
Ebola virus (EBOV) infection results in Ebola virus disease (EVD), an often severe disease with a nonspecific presentation. Since its recognition, periodic outbreaks of EVD continue to occur in sub-Saharan Africa. The 2013-2016 West African EVD outbreak was the largest recorded, resulting in a substantial cohort of EVD survivors with persistent health complaints and variable immune responses. In this study, we characterize humoral immune responses in EVD survivors and their contacts in Eastern Sierra Leone...
May 27, 2024: Journal of Infectious Diseases
https://read.qxmd.com/read/38800447/diagnostic-reliability-of-c-kit-cd117-in-salivary-gland-tumours-a-systematic-review-and-meta-analysis
#24
REVIEW
Gopikrishnan Vijayakumar, Mala Kamboj, Anjali Narwal, Gitika Sharma
c-KIT is an important diagnostic marker in salivary gland tumours and is expressed in most adenoid cystic carcinomas. Histologically similar salivary gland tumours with variable immunohistochemical expression for c-KIT pose a challenge and make diagnostic reliability ambivalent. An electronic search was performed in MEDLINE by PubMed, Google Scholar, Scopus, Trip, Cochrane Library, and EMBASE up to 31 December 2023, without period restriction. The articles that investigated CD117 or c-KIT in salivary gland tumours were included for review...
2024: Journal of Oral and Maxillofacial Pathology: JOMFP
https://read.qxmd.com/read/38799691/descriptive-study-on-substance-uses-and-risk-of-sexually-transmitted-infections-in-the-practice-of-chemsex-in-spain
#25
JOURNAL ARTICLE
Pablo Del Pozo-Herce, Enrique Baca-García, Antonio Martínez-Sabater, Elena Chover-Sierra, Vicente Gea-Caballero, Javier Curto-Ramos, Michal Czapla, Piotr Karniej, Jesús Martínez-Tofe, Mercedes Sánchez-Barba, Regina Ruiz de Viñaspre, Raúl Juárez-Vela
BACKGROUND: In recent years, there has been an increasing use of sex-related substances (known as "Chemsex") to facilitate, intensify, and prolong the sexual experience of men who have sex with men. This phenomenon poses a public health problem, increasing the risk of sexually transmitted infections (STIs) and mental disorders. OBJECTIVE: The primary aim of this study was to delve into the correlation between substance use and sexual health, specifically examining the association between different substances used and the risk of sexually transmitted infections (STIs) in the context of Chemsex in Spain...
2024: Frontiers in Public Health
https://read.qxmd.com/read/38799682/-i-don-t-know-if-i-can-keep-doing-this-a-qualitative-investigation-of-surgeon-burnout-and-opportunities-for-organization-level-improvement
#26
JOURNAL ARTICLE
Kestrel McNeill, Sierra Vaillancourt, Stella Choe, Ilun Yang, Ranil Sonnadara
INTRODUCTION: Burnout is a pressing issue within surgical environments, bearing considerable consequences for both patients and surgeons alike. Given its prevalence and the unique contextual factors within academic surgical departments, it is critical that efforts are dedicated to understanding this issue. Moreover, active involvement of surgeons in these investigations is critical to ensure viability and uptake of potential strategies in their local setting. Thus, the purpose of this study was to explore surgeons' experiences with burnout and identify strategies to mitigate its drivers at the level of the organization...
2024: Frontiers in Public Health
https://read.qxmd.com/read/38799276/electronic-real-time-monitoring-reveals-limited-adherence-to-long-term-opioid-prescriptions-in-pain-patients
#27
JOURNAL ARTICLE
David C Houghton, Christina R Merritt, Sierra N Miller, Jasmine M Mitchell, David Parker, Jonathan D Hommel, Kathryn A Cunningham, Denise M Wilkes
BACKGROUND: Pain management physicians are increasingly focused on limiting prescription opioid abuse, yet existing tools for monitoring adherence have limited accuracy. Medication event monitoring system (MEMS) is an emerging technology for tracking medication usage in real-time but has not been tested in chronic pain patients on long-term opioid regimens. OBJECTIVE: We conducted a pilot clinical trial to investigate the utility of MEMS for monitoring opioid adherence and compared to traditional methods including self-report diaries, urine drug screen (UDS), and physicians' opinions...
2024: Journal of Pain Research
https://read.qxmd.com/read/38797718/developing-the-self-determination-of-children-and-young-people-with-intellectual-disabilities-in-schools-a-systematic-review-of-the-literature
#28
REVIEW
Sierra Angelina Willow, Iva Strnadová, Joanne Danker
BACKGROUND: Self-determination is associated with lifelong positive outcomes. Students with intellectual disabilities typically have lower self-determination than their peers. Universal basic education access offers schools the opportunity to rectify this disparity. This is the first systematic review investigating the school-based practices that target self-determination development for students with intellectual disabilities. METHOD: The review follows the PRISMA guidelines, spanning five databases (ProQuest databases, EMBASE, Scopus, Sage Journals, Taylor and Francis Online) from 2006 to 2021...
July 2024: Journal of Applied Research in Intellectual Disabilities: JARID
https://read.qxmd.com/read/38796790/illumination-matters-part-i-comparative-analysis-of-light-sources-and-illumination-in-flexible-ureteroscopy-fundamental-findings-from-a-pearls-analysis
#29
COMPARATIVE STUDY
Jia-Lun Kwok, Vincent De Coninck, Mariela Corrales, Alba Sierra, Frédéric Panthier, Eugenio Ventimiglia, Vineet Gauhar, Florian Alexander Schmid, Manuela Hunziker, Cédric Poyet, Daniel Eberli, Olivier Traxer, Etienne Xavier Keller
PURPOSE: Illumination characteristics of flexible ureteroscopes have been evaluated in air, but not in saline, the native operative medium for endourology. The aim was to evaluate light properties of contemporary ureteroscopes in air versus saline, light distribution analysis, and color temperature. METHODS: We evaluated the Storz Flex-Xc and Flex-X2s, Olympus V3 and P7, Pusen 7.5F and 9.2F, and OTU WiScope using a 3D printed black target board in-vitro model submerged in saline...
May 26, 2024: World Journal of Urology
https://read.qxmd.com/read/38794482/antibacterial-and-antibiofilm-potential-of-ethanolic-extracts-of-duguetia-vallicola-annonaceae-against-in-hospital-isolates-of-pseudomonas-aeruginosa
#30
JOURNAL ARTICLE
Orfa Inés Contreras-Martínez, Daniela Sierra-Quiroz, Alberto Angulo-Ortíz
Pseudomonas aeruginosa is an opportunistic pathogen that is especially dominant in people with cystic fibrosis; the drug resistance expressed by this pathogen and its capacity for adaptation poses a significant challenge to its treatment and control, thereby increasing morbidity and mortality rates globally. In this sense, the search for new treatment alternatives is imminent today, with products of plant origin being an excellent alternative for use. The objective of this research was to evaluate the antibacterial and antibiofilm potential and to explore the possible effect of ethanolic extracts from the wood and bark of Duguetia vallicola on the cell membrane...
May 18, 2024: Plants (Basel, Switzerland)
https://read.qxmd.com/read/38794292/trends-in-targeted-therapy-usage-in-inflammatory-bowel-disease-trendy-study-of-eneida
#31
JOURNAL ARTICLE
Celia Gómez-Labrador, Elena Ricart, Marisa Iborra, Eva Iglesias, María Dolores Martín-Arranz, Luisa de Castro, Ruth De Francisco, Francisco Javier García-Alonso, Ana Sanahuja, Carla J Gargallo-Puyuelo, Francisco Mesonero, María José Casanova, Míriam Mañosa, Montserrat Rivero, Marta Calvo, Mónica Sierra-Ausin, Carlos González-Muñoza, Xavier Calvet, Santiago García-López, Jordi Guardiola, Lara Arias García, Lucía Márquez-Mosquera, Ana Gutiérrez, Yamile Zabana, Mercè Navarro-Llavat, Rufo Lorente Poyatos, Marta Piqueras, Leyanira Torrealba, Fernando Bermejo, Ángel Ponferrada-Díaz, José L Pérez-Calle, Manuel Barreiro-de Acosta, Coral Tejido, José Luis Cabriada, Ignacio Marín-Jiménez, Óscar Roncero, Yolanda Ber, Luis Fernández-Salazar, Blau Camps Aler, Alfredo J Lucendo, Jordina Llaó, Luis Bujanda, Carmen Muñoz Villafranca, Eugeni Domènech, María Chaparro, Javier P Gisbert
Markers that allow for the selection of tailored treatments for individual patients with inflammatory bowel diseases (IBD) are yet to be identified. Our aim was to describe trends in real-life treatment usage. For this purpose, patients from the ENEIDA registry who received their first targeted IBD treatment (biologics or tofacitinib) between 2015 and 2021 were included. A subsequent analysis with Machine Learning models was performed. The study included 10,009 patients [71% with Crohn's disease (CD) and 29% with ulcerative colitis (UC)]...
May 8, 2024: Pharmaceutics
https://read.qxmd.com/read/38793882/experimental-study-of-white-light-interferometry-in-mach-zehnder-interferometers-based-on-standard-single-mode-fiber
#32
JOURNAL ARTICLE
José Luis Cano-Perez, Jaime Gutiérrez-Gutiérrez, Christian Perezcampos-Mayoral, Eduardo L Pérez-Campos, María Del Socorro Pina-Canseco, Lorenzo Tepech-Carrillo, Marciano Vargas-Treviño, Erick Israel Guerra-Hernández, Abraham Martínez-Helmes, Julián Moisés Estudillo-Ayala, Juan Manuel Sierra-Hernández, Roberto Rojas-Laguna
In this work, we experimentally analyzed and demonstrated the performance of an in-line Mach-Zehnder interferometer in the visible region, with an LED light source. The different waist diameter taper and asymmetric core-offset interferometers proposed used a single-mode fiber (SMF). The visibility achieved was V = 0.14 with an FSR of 23 nm for the taper MZI structure and visibilities of V = 0.3, V = 0.27, and V = 0.34 with FSRs of 23 nm, 17 nm, and 8 nm and separation lengths L of 2.5 cm, 4.0 cm, and 5.0 cm between the core-offset structure, respectively...
May 10, 2024: Sensors
https://read.qxmd.com/read/38792346/detrimental-impact-of-atrial-fibrillation-among-patients-hospitalized-for-acute-exacerbation-of-copd-results-of-a-population-based-study-in-spain-from-2016-to-2021
#33
JOURNAL ARTICLE
Javier de-Miguel-Diez, Ana Lopez-de-Andres, José J Zamorano-Leon, Valentín Hernández-Barrera, Natividad Cuadrado-Corrales, Ana Jimenez-Sierra, Rodrigo Jimenez-Garcia, David Carabantes-Alarcon
Background/Objectives : To analyze changes in the prevalence of atrial fibrillation (AF) in patients hospitalized for acute exacerbation of chronic obstructive pulmonary disease (AE-COPD); to evaluate hospital outcomes according to AF status, assessing sex differences; to identify factors associated with AF presence; and to analyze variables associated with in-hospital mortality (IHM) in AE-COPD patients with AF. Methods : We used data from the Registry of Specialized Care Activity-Basic Minimum Data Set (RAE-CMBD) to select patients aged ≥40 years with COPD in Spain (2016-2021)...
May 9, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38791841/resilience-and-positive-wellbeing-experienced-by-5-12-year-old-children-with-refugee-backgrounds-in-australia-the-childhood-resilience-study
#34
JOURNAL ARTICLE
Elisha Riggs, Deirdre Gartland, Josef Szwarc, Mardi Stow, Georgia Paxton, Stephanie J Brown
Refugee research tends to be deficit based and focused on the risks threatening positive adaptation and wellbeing. High rates of mental (and physical) health issues have been reported for refugee adults and children, including intergenerational trauma. This study uses the new Child Resilience Questionnaire (CRQ), co-designed with refugee background communities, to describe resilience and positive wellbeing experienced by children of refugee-background. The Childhood Resilience Study (CRS) recruited 1132 families with children aged 5-12 years in Victoria and South Australia, Australia...
May 15, 2024: International Journal of Environmental Research and Public Health
https://read.qxmd.com/read/38791117/inhibition-of-shikimate-kinase-from-methicillin-resistant-staphylococcus-aureus-by-benzimidazole-derivatives-kinetic-computational-toxicological-and-biological-activity-studies
#35
JOURNAL ARTICLE
Lluvia Rios-Soto, Alicia Hernández-Campos, David Tovar-Escobar, Rafael Castillo, Erick Sierra-Campos, Mónica Valdez-Solana, Alfredo Téllez-Valencia, Claudia Avitia-Domínguez
Antimicrobial resistance (AMR) is one of the biggest threats in modern times. It was estimated that in 2019, 1.27 million deaths occurred around the globe due to AMR. Methicillin-resistant Staphylococcus aureus (MRSA) strains, a pathogen considered of high priority by the World Health Organization, have proven to be resistant to most of the actual antimicrobial treatments. Therefore, new treatments are required to be able to manage this increasing threat. Under this perspective, an important metabolic pathway for MRSA survival, and absent in mammals, is the shikimate pathway, which is involved in the biosynthesis of chorismate, an intermediate for the synthesis of aromatic amino acids, folates, and ubiquinone...
May 7, 2024: International Journal of Molecular Sciences
https://read.qxmd.com/read/38790776/acerola-cherry-and-rosemary-extracts-improve-color-and-delay-lipid-oxidation-in-previously-frozen-beef
#36
JOURNAL ARTICLE
Jessie B Van Buren, Brooklyn Epperson, Sierra Jepsen, Mikayla Heimbuch, Kayleen Oliver, James Nasados, Phillip D Bass, Michael J Colle
Extending the shelf life of exported beef could increase international demand and producer profits. The objective was to evaluate the effects of topically applying combinations of acerola cherry powder and rosemary extract on the shelf life of frozen-thawed bone-in beef short rib and chuck roll steaks. Chuck rolls (IMPS 116A; N = 9) and bone-in short ribs (IMPS 123A; N = 18) were aged (7 d; 0 °C), frozen (30 d; -20 °C), and thawed (60-72 h; 0 °C). Steaks measuring 1.02 cm thick were treated and subjected to a 4 d retail display...
May 10, 2024: Foods (Basel, Switzerland)
https://read.qxmd.com/read/38790604/prevalence-and-characteristics-of-sleep-disorders-in-children-aged-7-17-insights-from-parental-observations-at-the-dental-office
#37
JOURNAL ARTICLE
Montserrat Diéguez-Pérez, Laura Burgueño-Torres, Guillermo Reichard-Monefeldt, Fanny Esther Tapia-Sierra, Jesús Miguel Ticona-Flores
Sleep disorders (SD) in children is a topic of great relevance due to their impact on a child's general health. This has led us to study their prevalence and the factors that disturb them in the developing population. Using a validated Likert-type questionnaire, different behaviors observed by the parents during the different phases of their children's sleep were evaluated during the last 6 months. A total of 206 children between the ages of 7 and 17 who attended a dental office participated in the study. The prevalence of SD was 47...
May 20, 2024: Children
https://read.qxmd.com/read/38789604/genetic-parameters-for-milk-yield-and-reproductive-traits-in-honduran-holstein-cattle
#38
JOURNAL ARTICLE
Raciel Javier Estrada-León, Manuel Antonio Valladares-Rodas, Angel Carmelo Sierra Vázquez, Juan Gabriel Magaña Monforte, José Candelario Segura Correa, Gaspar Manuel Parra-Bracamonte
The aim of this study was to estimate the (co)variance components and genetic parameters for milk yield adjusted to 305d (MY305), calving-to-conception interval (CCI), number of services per conception (NSC) and calving interval (CI) of Honduran Holstein cows, by fitting a bivariate animal model using Maximum Restricted Likelihood procedures. Model included the fixed effects of calving number, the contemporary calving group (farm-season-year of calving and the cow age as covariate). The estimated means and standard deviations for MY, CCI, NSC and CI were, 5098...
May 25, 2024: Tropical Animal Health and Production
https://read.qxmd.com/read/38789266/prevalence-and-viral-suppression-of-hepatitis-b-virus-infection-among-people-living-with-hiv-on-antiretroviral-therapy-in-sierra-leone
#39
JOURNAL ARTICLE
Jin-Wen Song, Sulaiman Lakoh, Si-Yuan Chen, Mohamed Boie Jalloh, Stephen Sevalie, Mamadu Baldeh, Mohamed K Nyambe, Victoria Donicia Nicholas, George Yendewa, Fu-Sheng Wang, Guang Yang
OBJECTIVE: Sub-Saharan Africa is one of the regions with the highest burdens of HIV and hepatitis B virus (HBV), but data on the impact of antiretroviral therapy (ART) on HBV DNA suppression is limited. In this study, we aimed to determine the prevalence and associated factors of a positive hepatitis B surface antigen (HBsAg) among people living with HIV, and assess the suppression of ART on HBV replication in people living with HIV in Sierra Leone. METHODS: A cross-sectional study was designed to recruit people living with HIV aged 18 years or older in ten public hospitals in Sierra Leone between August 2022 and January 2023...
May 24, 2024: Sexually Transmitted Infections
https://read.qxmd.com/read/38789045/neuropsychiatric-diagnoses-after-isotretinoin-initiation-in-pediatric-acne-patients-a-retrospective-cohort-study
#40
JOURNAL ARTICLE
Tapio Paljärvi, Tess McPherson, Courtney Thompson, Sierra Luciano, Kimmo Herttua, Seena Fazel
No abstract text is available yet for this article.
May 22, 2024: Journal of the American Academy of Dermatology
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