Terenzio Cosio, Roberta Gaziano, Carla Fontana, Enrico Salvatore Pistoia, Rosalba Petruccelli, Marco Favaro, Francesca Pica, Silvia Minelli, Maria Cristina Bossa, Anna Altieri, Domenico Ombres, Nikkia Zarabian, Cartesio D'Agostini
Histoplasmosis is a globally distributed systemic infection caused by the dimorphic fungus Histoplasma capsulatum ( H. capsulatum ). This fungus can cause a wide spectrum of clinical manifestations, and the diagnosis of progressive disseminated histoplasmosis is often a challenge for clinicians. Although microscopy and culture remain the gold standard diagnostic tests for Histoplasma identification, matrix-assisted laser desorption ionization time of flight mass spectrometry (MALDI-TOF MS) has emerged as a method of microbial identification suitable for the confirmation of dimorphic fungi...
October 15, 2023: Journal of Fungi (Basel, Switzerland)