keyword
https://read.qxmd.com/read/38572213/associated-factors-of-cardiopulmonary-resuscitation-outcomes-a-cohort-study-on-an-adult-in-hospital-cardiac-arrest-registry
#41
JOURNAL ARTICLE
Parin Rattananon, Welawat Tienpratarn, Chaiyaporn Yuksen, Supassorn Aussavanodom, Natthaphong Thiamdao, Phatcha Termkijwanich, Suraphong Phongsawad, Parama Kaninworapan, Kanda Tantasirin
INTRODUCTION: In-hospital cardiac arrest (IHCA) remains a substantial cause of morbidity and mortality for hospitalized patients worldwide. This study aimed to identify associated factors of return of spontaneous circulation (ROSC) and survival with favorable neurological outcomes of IHCA patients. METHOD: A two-year retrospective cohort study was conducted at a university-based tertiary care hospital in Bangkok, Thailand, studying adult patients aged ≥ 18 years with IHCA from January 2021 to December 2022...
2024: Archives of Academic Emergency Medicine
https://read.qxmd.com/read/38558288/-shark-fin-electrocardiogram-pattern-in-takotsubo-cardiomyopathy
#42
JOURNAL ARTICLE
Luísa Gomes Rocha, Gonçalo Costa, Lino Gonçalves
No abstract text is available yet for this article.
April 1, 2024: Internal and Emergency Medicine
https://read.qxmd.com/read/38550740/navigating-the-fine-line-between-focal-atrial-tachycardia-and-atrial-flutter
#43
Feisal Rahimpour, Roohullah Hemmati, Mohsen Anafje, Hadis Soltani, Haghjoo Majid, Pouya Ebrahimi
Focal atrial tachycardia (FAT) is an organized atrial rhythm >100 beats per minute initiated from a discrete origin and spreading over both atria in a centrifugal pattern. The arrhythmia may be sustained or incessant. Dynamic forms with recurrent interruptions and reinitiating may be frequent. In this report, we present a 36-year-old man who came to the emergency room complaining of palpitation and shortness of breath. All laboratory evaluations were normal. With an initial electrocardiogram (ECG) the patient was admitted with the initial diagnosis of atrial flutter...
April 2024: Clinical Case Reports
https://read.qxmd.com/read/38542006/catecholaminergic-polymorphic-ventricular-tachycardia-clinical-characteristics-diagnostic-evaluation-and-therapeutic-strategies
#44
REVIEW
Abhinav Aggarwal, Anton Stolear, Md Mashiul Alam, Swarnima Vardhan, Maxim Dulgher, Sun-Joo Jang, Stuart W Zarich
Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a severe hereditary arrhythmia syndrome predominantly affecting children and young adults. It manifests through bidirectional or polymorphic ventricular arrhythmia, often culminating in syncope triggered by physical exertion or emotional stress which can lead to sudden cardiac death. Most cases stem from mutations in the gene responsible for encoding the cardiac ryanodine receptor ( RyR2 ), or in the Calsequestrin 2 gene ( CASQ2 ), disrupting the handling of calcium ions within the cardiac myocyte sarcoplasmic reticulum...
March 20, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38538355/-value-of-cardiodynamicsgram-in-early-diagnosis-of-patients-with-acute-coronary-syndrome
#45
JOURNAL ARTICLE
Xiubing Gong, Yanan Gu, Xiangyue Jiang, Qingli Dou
OBJECTIVE: To explore the value of cardiodynamicsgram (CDG) obtained from electrocardiogram (ECG) data by radial basis functionradial basis function (RBF) neural network in early diagnosis of patients with acute coronary syndrome (ACS). METHODS: Retrospective analysis method was used. Patients with chest pain as the main initial symptom in the emergency department of Baoan District People's Hospital of Shenzhen from October 2021 to September 2022 were enrolled. Baseline data were collected, including gender, age, smoking history, family history of coronary heart disease and history of hypertension, diabetes, hyperlipidemia, and atherosclerosis...
March 2024: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
https://read.qxmd.com/read/38533633/clinical-trial-randomized-controlled-trial-of-linaclotide-in-children-aged-6-17-years-with-functional-constipation
#46
JOURNAL ARTICLE
Carlo Di Lorenzo, Samuel Nurko, Jeffrey S Hyams, Gerardo Rodriguez-Araujo, Cristina Almansa, Valentina Shakhnovich, Miguel Saps, Michael Simon
OBJECTIVES: Linaclotide, a guanylate cyclase-C agonist, was recently approved in the United States for treatment of children 6-17 years old with functional constipation (FC). This study evaluated the safety and efficacy of several linaclotide doses in children 6-17 years old with FC. METHODS: In this multicenter, randomized, double-blind, placebo-controlled phase 2 study, 173 children with FC (based on Rome III criteria) were randomized to once-daily linaclotide (A: 9 or 18 μg, B: 18 or 36 μg, or C: 36 or 72 μg) or placebo in a 1:1:1:1 ratio for 6- to 11-year-olds (dosage determined by weight: 18 to <35 or ≥35 kg) and linaclotide (18, 36, 72, or 145 μg) or placebo in a 1:1:1:1:1 ratio for 12- to 17-year-olds...
March 27, 2024: Journal of Pediatric Gastroenterology and Nutrition
https://read.qxmd.com/read/38527251/introducing-virtual-reality-in-a-stemi-coronary-syndrome-course-qualitative-evaluation-with-nurses-and-doctors
#47
JOURNAL ARTICLE
Alessandro Forgiarini, Laura Deroma, Fabio Buttussi, Nicola Zangrando, Sabrina Licata, Francesca Valent, Luca Chittaro, Antonio Di Chiara
In the increasing number of medical education topics taught with virtual reality (VR), the prehospital management of ST-segment elevation myocardial infarction (STEMI) had not been considered. This article proposes an implemented VR system for STEMI training and introduces it in an institutional course addressed to emergency nurses and case manager (CM) doctors. The system comprises three different applications to, respectively, allow (a) the course instructor to control the conditions of the virtual patient, (b) the CM to communicate with the nurse in the virtual field and receive from him/her the patient's parameters and electrocardiogram, and (c) the nurse to interact with the patient in the immersive VR scenario...
March 25, 2024: Cyberpsychology, Behavior and Social Networking
https://read.qxmd.com/read/38524089/bradycardia-renal-failure-atrioventricular-block-shock-and-hyperkalemia-brash-syndrome-emergence-in-a-unique-intersection-of-covid-19-and-end-stage-renal-disease-a-case-report
#48
Tutul Chowdhury, Sindhu C Pokhriyal, Uma Gupta, Kalendra Kunwar, Kiran Hashmi, Sauraj Devkota, Morris Kopyt, Andleeb Sherazi
Bradycardia, renal failure, atrioventricular (AV) block, shock, and hyperkalemia (BRASH) syndrome is a rare clinical entity that poses challenges for healthcare practitioners. It is characterized by bradycardia, renal failure, atrioventricular (AV) obstruction, shock, and hyperkalemia. This case is an interesting instance of BRASH syndrome in the setting of COVID-19 infection and end-stage renal disease (ESRD). Initial laboratory results revealed macrocytic anemia, renal dysfunction, acidosis, and mild hyponatremia, along with hyperkalemia...
February 2024: Curēus
https://read.qxmd.com/read/38523487/a-phase-1-randomized-double-blind-placebo-controlled-single-ascending-dose-study-to-evaluate-the-pharmacokinetics-immunogenicity-safety-and-tolerability-after-subcutaneous-administration-of-tozorakimab-in-healthy-chinese-participants
#49
JOURNAL ARTICLE
Yunfei Li, Hua Zhang, Hitesh Pandya, Liyan Miao, Fred Reid, Eulalia Jimenez, Muhammad Waqas Sadiq, Rachel Moate, Alejhandra Lei, Xiao-Hong Zhou, Chris Kell, Junjie Ding, Guanlin Zhang, Lina Zhao, Xiaoyun Ge
Tozorakimab is a high-affinity human immunoglobulin G1 monoclonal antibody that neutralizes interleukin (IL)-33, an IL-1 family cytokine. This phase 1, single-center, randomized, double-blind, placebo-controlled, single ascending dose study (NCT05070312) evaluated tozorakimab in a healthy Chinese population. Outcomes included the characterization of the pharmacokinetic (PK) profile and immunogenicity of tozorakimab. Safety outcomes included treatment-emergent adverse events (TEAEs) and clinical laboratory, electrocardiogram, and vital sign parameters...
March 25, 2024: Clinical Pharmacology in Drug Development
https://read.qxmd.com/read/38521713/obstructive-myocardial-infarction-with-normal-automated-ecg-interpretation-a-case-report
#50
Daniel Herzog, Christopher N Scavelli
Emergency Medicine physicians experience a significant number of interruptions throughout their work day. One common cause of interruptions is the immediate interpretation of triage electrocardiograms (ECGs). Recent studies have suggested that ECGs interpreted as normal via automated analysis by the ECG machine rarely require urgent cardiac intervention and suggested that providers may not have to be interrupted to interpret these "normal" ECGs. We describe the case of a patient who presented to the Emergency Department (ED) with chest pain and an ECG interpreted as normal by an automated reading from the ECG machine, despite having acute coronary syndrome requiring emergent intervention...
May 2024: American Journal of Emergency Medicine
https://read.qxmd.com/read/38505483/international-evaluation-of-an-artificial-intelligence-powered-electrocardiogram-model-detecting-acute-coronary-occlusion-myocardial-infarction
#51
JOURNAL ARTICLE
Robert Herman, Harvey Pendell Meyers, Stephen W Smith, Dario T Bertolone, Attilio Leone, Konstantinos Bermpeis, Michele M Viscusi, Marta Belmonte, Anthony Demolder, Vladimir Boza, Boris Vavrik, Viera Kresnakova, Andrej Iring, Michal Martonak, Jakub Bahyl, Timea Kisova, Dan Schelfaut, Marc Vanderheyden, Leor Perl, Emre K Aslanger, Robert Hatala, Wojtek Wojakowski, Jozef Bartunek, Emanuele Barbato
AIMS: A majority of acute coronary syndromes (ACS) present without typical ST elevation. One-third of non-ST-elevation myocardial infarction (NSTEMI) patients have an acutely occluded culprit coronary artery [occlusion myocardial infarction (OMI)], leading to poor outcomes due to delayed identification and invasive management. In this study, we sought to develop a versatile artificial intelligence (AI) model detecting acute OMI on single-standard 12-lead electrocardiograms (ECGs) and compare its performance with existing state-of-the-art diagnostic criteria...
March 2024: European heart journal. Digital health
https://read.qxmd.com/read/38505481/detection-of-acute-coronary-occlusion-with-a-novel-mobile-electrocardiogram-device-a-pilot-study
#52
JOURNAL ARTICLE
Alejandra Zepeda-Echavarria, Rutger R van de Leur, Melle Vessies, Nynke M de Vries, Meike van Sleuwen, Rutger J Hassink, Thierry X Wildbergh, J L van Doorn, Rien van der Zee, Pieter A Doevendans, Joris E N Jaspers, René van Es
AIMS: Many portable electrocardiogram (ECG) devices have been developed to monitor patients at home, but the majority of these devices are single lead and only intended for rhythm disorders. We developed the miniECG, a smartphone-sized portable device with four dry electrodes capable of recording a high-quality multi-lead ECG by placing the device on the chest. The aim of our study was to investigate the ability of the miniECG to detect occlusive myocardial infarction (OMI) in patients with chest pain...
March 2024: European heart journal. Digital health
https://read.qxmd.com/read/38497695/diagnosis-and-management-of-paroxysmal-supraventricular-tachycardia
#53
JOURNAL ARTICLE
Gary Peng, Paul C Zei
IMPORTANCE: Paroxysmal supraventricular tachycardia (PSVT), defined as tachyarrhythmias that originate from or conduct through the atria or atrioventricular node with abrupt onset, affects 168 to 332 per 100 000 individuals. Untreated PSVT is associated with adverse outcomes including high symptom burden and tachycardia-mediated cardiomyopathy. OBSERVATIONS: Approximately 50% of patients with PSVT are aged 45 to 64 years and 67.5% are female. Most common symptoms include palpitations (86%), chest discomfort (47%), and dyspnea (38%)...
February 20, 2024: JAMA
https://read.qxmd.com/read/38497129/transient-changes-in-the-st-t-waveform-mimicking-myocardial-infarction-in-a-child-with-near-drowning-a-case-report
#54
JOURNAL ARTICLE
Jianmin Zhang, Haitao Lv, Xue Jiang, Yunjia Tang, Miao Hou
Drowning is a common cause of childhood morbidity and mortality worldwide. Anoxia, hypothermia, and metabolic acidosis are mainly responsible for this morbidity. Drowning may lead to multiple organ damage, especially cardiac damage, in cases in which severe hypothermia and hypoxemia occur. We report a case of a 4-year-old girl who was admitted to our hospital's Emergency Department because of drowning. She had elevated troponin I concentrations and ST-segment elevation with T wave inversion. However, cardiovascular computed tomography showed no obvious abnormalities in the coronary arteries...
March 2024: Journal of International Medical Research
https://read.qxmd.com/read/38490783/hypothermic-cardiac-arrest-a-case-report-of-an-unexpected-survivor-using-air-medical-transportation-in-nepal
#55
Ashim Subedi, Kishor Khanal, Ashim Regmi, Sagarika Panday, Rupesh Yadav, Pritina Nakarmi, Enish Shrestha, Prashanti Prasai, Ryan McHenry, Sanjaya Karki
This is a case of a 34-year-old man surviving hypothermic cardiac arrest with excellent neurologic recovery in Nepal. After 3 days without communication at an altitude of approximately 6,000 m, the patient was located in a crevasse and retrieved by a helicopter-supported search and rescue team. At first contact, he was reported to be breathing and shivering with appropriate pupillary response. The patient was then flown to a local teaching hospital where he was assessed on arrival and found to be in cardiac arrest with absence of spontaneous breathing and a central pulse and bilaterally fixed and dilated pupils...
2024: Air Medical Journal
https://read.qxmd.com/read/38490096/assessing-risk-of-major-adverse-cardiac-events-among-patients-with-chest-pain-and-cocaine-use-using-the-heart-score
#56
JOURNAL ARTICLE
Neeraja Murali, Afrah Ali, Robinson Okolo, Saad Pirzada, Benoit Stryckman, Lauren Day, Daniel Lemkin, Mark Sutherland, Zachary Dezman, Quincy K Tran
INTRODUCTION: Chest pain (CP), a common presentation in the emergency department (ED) setting, is associated with significant morbidity and mortality if emergency clinicians miss the diagnosis of acute coronary syndrome (ACS). The HEART (History, Electrocardiogram, Age, Risk Factors, Troponin) score had been validated for risk-stratification patients who are at high risk for ACS and major adverse cardiac events (MACE). However, the use of cocaine as a risk factor of the HEART score was controversial...
February 3, 2024: American Journal of Emergency Medicine
https://read.qxmd.com/read/38487120/hyperkalemia-induced-t-wave-oversensing-in-an-implantable-cardioverter-defibrillator
#57
Ariel Gonzalez, Hilton Franqui, Jose Lopez, Hector Banchs
A 66-year-old female with end-stage renal disease and heart failure with reduced ejection fraction, status post implantable cardioverter defibrillator (ICD) presented to the emergency department with dizziness and fatigue. An electrocardiogram showed sinus rhythm, complete atrioventricular block, and ventricular paced rhythm at 30 beats per minute (bpm). Device interrogation revealed a programmed VVI mode with a lower rate limit of 40 bpm and evidence of T wave oversensing. Serologic studies were remarkable for hyperkalemia (7...
February 2024: Curēus
https://read.qxmd.com/read/38487108/lyme-associated-pericarditis-a-case-report-and-literature-review
#58
Muhammad Atif Ameer, Sridhar Reddy Patlolla, Nimi Patel, Rahul Mehta, Maham Babar
Lyme disease is caused by  Borrelia burgdorferi (B. burgdorferi), which  is a spirochete transmitted by ticks of the genus  Ixodes . Complications related to the cardiovascular system usually occur in the early phase of infection, and the most common cardiovascular complication of Lyme disease is atrioventricular block, especially third-degree heart block. We report a case of a young Caucasian male patient who presented to the emergency department (ED) with complaints of chest pain and shortness of breath...
February 2024: Curēus
https://read.qxmd.com/read/38486759/an-arrhythmia-classification-approach-via-deep-learning-using-single-lead-ecg-without-qrs-wave-detection
#59
JOURNAL ARTICLE
Liong-Rung Liu, Ming-Yuan Huang, Shu-Tien Huang, Lu-Chih Kung, Chao-Hsiung Lee, Wen-Teng Yao, Ming-Feng Tsai, Cheng-Hung Hsu, Yu-Chang Chu, Fei-Hung Hung, Hung-Wen Chiu
Arrhythmia, a frequently encountered and life-threatening cardiac disorder, can manifest as a transient or isolated event. Traditional automatic arrhythmia detection methods have predominantly relied on QRS-wave signal detection. Contemporary research has focused on the utilization of wearable devices for continuous monitoring of heart rates and rhythms through single-lead electrocardiogram (ECG), which holds the potential to promptly detect arrhythmias. However, in this study, we employed a convolutional neural network (CNN) to classify distinct arrhythmias without QRS wave detection step...
March 15, 2024: Heliyon
https://read.qxmd.com/read/38482311/hyponatremia-induced-worsening-of-trigeminal-neuralgia-when-the-sodium-plays-the-game
#60
Mohammad Z Ansari, Rashmi Singh, Bijaya Mohanty, Sarita Kumari, Ashok Sunder
A 78-year-old elderly male who was on treatment for trigeminal neuralgia and hypertension was brought to the emergency with altered sensorium. His vital parameters were within normal limits; however, the arterial blood gas analysis showed severe hyponatremia. He was admitted to the ward, where further workup was carried out and hyponatremia correction started. He had a sudden worsening in his facial pain before he landed in encephalopathy. His medications (oxcarbazepine and chlorthalidone) that could cause hyponatremia were stopped, and judicious correction of hyponatremia was done...
January 2024: Journal of Family Medicine and Primary Care
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