Lu He, Jinke Yang, Yu Hao, Xing Yang, Xijuan Shi, Dajun Zhang, Dengshuai Zhao, Wenqian Yan, Xintian Bie, Lingling Chen, Guohui Chen, Siyue Zhao, Xiangtao Liu, Haixue Zheng, Keshan Zhang
DEAD-box decapping enzyme 20 (DDX20) is a putative RNA-decapping enzyme that can be identified by the conserved motif Asp-Glu-Ala-Asp (DEAD). Cellular processes involve numerous RNA secondary structure alterations, including translation initiation, nuclear and mitochondrial splicing, and assembly of ribosomes and spliceosomes. DDX20 reportedly plays an important role in cellular transcription and post-transcriptional modifications. On the one hand, DDX20 can interact with various transcription factors and repress the transcriptional process...
October 20, 2023: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry