Nicola Veronese, Luisa Solimando, Francesco Bolzetta, Stefania Maggi, Jess G Fiedorowicz, Arnav Gupta, Nicholas Fabiano, Stanley Wong, Laurent Boyer, Guillaume Fond, Elena Dragioti, Ligia J Dominguez, Mario Barbagallo, Stefano Romagnoli, Giuseppe Bellelli, Marco Solmi
Delirium is a common condition across different settings and populations. The interventions for preventing and managing this condition are still poorly known. The aim of this umbrella review is to synthesize and grade all preventative and therapeutic interventions for delirium. We searched five databases from database inception up to March 15th, 2023 and we included meta-analyses of randomized controlled trials (RCTs) to decrease the risk of/the severity of delirium. From 1959 records after deduplication, we included 59 systematic reviews with meta-analyses, providing 110 meta-analytic estimates across populations, interventions, outcomes, settings, and age groups (485 unique RCTs, 172,045 participants)...
April 26, 2024: Ageing Research Reviews