Tiago Nicoliche, Cynthia Silva Bartolomeo, Robertha Mariana Rodrigues Lemes, Gabriela Cruz Pereira, Tamires Alves Nunes, Rafaela Brito Oliveira, Arthur Luiz Miranda Nicastro, Érica Novaes Soares, Brenno Fernandes da Cunha Lima, Beatriz Moreira Rodrigues, Juliana Terzi Maricato, Liria Hiromi Okuda, Mirela Inês de Sairre, Carla Máximo Prado, Rodrigo Portes Ureshino, Roberta Sessa Stilhano
COVID-19, caused by SARS-CoV-2, affects neuronal cells, causing several symptoms such as memory loss, anosmia and brain inflammation. Curcuminoids (Me08 e Me23) and curcumin (CUR) are derived from Curcuma Longa extract (EXT). Many therapeutic actions have been linked to these compounds, including antiviral action. Given the severe implications of COVID-19, especially within the central nervous system, our study aims to shed light on the therapeutic potential of curcuminoids against SARS-CoV-2 infection, particularly in neuronal cells...
May 10, 2024: Scientific Reports