keyword
https://read.qxmd.com/read/38547407/increased-risk-of-myocarditis-and-arrythmias-in-anti-ku-positive-scleroderma-myositis-overlap-patients-a-case-series
#1
JOURNAL ARTICLE
Aashik Bhalodia, Kevin Bermea, Jen Schmidt, Nisha Gilotra, Andreas S Barth, Luigi Adamo, Julie J Paik
No abstract text is available yet for this article.
March 28, 2024: Rheumatology
https://read.qxmd.com/read/38547403/prevalence-characteristics-and-outcome-of-subclinical-vasculitis-in-polymyalgia-rheumatica-a-retrospective-cohort-study
#2
JOURNAL ARTICLE
Lien Moreel, Lennert Boeckxstaens, Albrecht Betrains, Timo Smans, Geert Molenberghs, Koen Van Laere, Ellen De Langhe, Steven Vanderschueren, Daniel Blockmans
OBJECTIVES: Two recent meta-analyses reported subclinical vasculitis in 22-23% of patients with polymyalgia rheumatica (PMR). We aimed to evaluate the prevalence, characteristics, and outcome of subclinical vasculitis among our PMR patients. METHODS: Consecutive patients with GCA/PMR spectrum disease with isolated PMR symptoms who underwent FDG PET imaging between 2003-2020 and who were followed for ≥6 months, were included retrospectively. Vasculitis was defined as FDG uptake ≥ grade 2 in any vessel...
March 28, 2024: Rheumatology
https://read.qxmd.com/read/38547392/rheumatoid-arthritis-patients-perspective-on-the-use-of-prediction-models-in-clinical-decision-making
#3
JOURNAL ARTICLE
Marianne A Messelink, Sina Fadaei, Lise M Verhoef, Paco Welsing, Nienke C Nijhof, Heleen Westland
OBJECTIVES: A rapidly expanding number of prediction models is being developed aiming to improve rheumatoid arthritis (RA) diagnosis and treatment. However, few are actually implemented in clinical practice. This study explores factors influencing the acceptance of prediction models in clinical decision-making by RA patients. METHODS: A qualitative study design was used with thematic analysis of semi-structured interviews. Purposive sampling was applied to capture a complete overview of influencing factors...
March 28, 2024: Rheumatology
https://read.qxmd.com/read/38547341/igg4-related-disease-complicated-with-diffuse-and-chronic-gastrointestinal-inflammation-leading-to-small-intestinal-perforation
#4
JOURNAL ARTICLE
Kazuma Ino, Yoshiyuki Arinuma, Masashi Akiya, Sabine Kajita, Sosei Okina, Junichi Sakamoto, Tomoki Tanaka, Yu Matsueda, Tatsuhiko Wada, Sumiaki Tanaka, Kenji Oku, Kunihiro Yamaoka
Immunoglobulin (Ig) G4-related disease (IgG4-RD) is a systemic inflammatory disease characterized by elevated serum IgG4, IgG4+ cell infiltration, storiform fibrosis, and obliterative phlebitis. While IgG4-RD can affect various organs, gastrointestinal tract involvement is less common. Here, we report a 70-year-old female with IgG4-RD complicated with diffuse and chronic gastrointestinal inflammation which led to small intestinal perforation. She had been suffering from anorexia, abdominal pain, vomiting, and diarrhea, and hospitalized due to recurrent ileus...
March 28, 2024: Modern rheumatology case reports
https://read.qxmd.com/read/38546745/clinical-and-laboratory-characteristics-of-early-onset-and-delayed-onset-lupus-nephritis-patients-a-single-center-retrospective-study
#5
JOURNAL ARTICLE
Joanna Kosałka-Węgiel, Radosław Dziedzic, Andżelika Siwiec-Koźlik, Magdalena Spałkowska, Mamert Milewski, Joanna Żuk-Kuwik, Lech Zaręba, Stanisława Bazan-Socha, Mariusz Korkosz
BACKGROUND: Lupus nephritis (LN) manifests systemic lupus erythematosus (SLE) and is characterized by various clinical and laboratory features. This study aimed to comprehensively evaluate the characteristics of LN patients according to the time of LN diagnosis: early-onset (LN diagnosed within one year from SLE diagnosis) vs. delayed-onset (LN diagnosed more than one year after SLE diagnosis). METHODS: We conducted a retrospective analysis of medical records from all SLE patients treated at the University Hospital in Kraków, Poland, from 2012 to 2022...
March 28, 2024: Rheumatology International
https://read.qxmd.com/read/38546125/correction-to-association-of-the-clinical-components-in-the-distal-interphalangeal-joint-synovio-entheseal-complex-and-subsequent-response-to-ixekizumab-or-adalimumab-in-psoriatic-arthritis
#6
https://read.qxmd.com/read/38545801/systemic-lupus-erythematosus-one-year-in-review-2024
#7
REVIEW
Davide Schilirò, Ettore Silvagni, Benedetta Ciribè, Federico Fattorini, Vincenzo Maccarrone, Elena Elefante, Viola Signorini, Dina Zucchi, Chiara Cardelli, Alessandra Bortoluzzi, Chiara Tani
Systemic lupus erythematosus (SLE) is classically regarded as the landmark of systemic autoimmune diseases, characterised by protean, multi-systemic manifestations and a highly variable clinical course.Over the last years, both clinical and translational clinical research efforts led to significant steps forward in management and treatment of SLE. However, numerous aspects of SLE, from pathogenesis to treatment, still remain challenging, and several unmet needs persist for both patients and physicians. Following the previous annual reviews of this series, herewith, we aim to report the most relevant new updates on SLE, issued in 2023...
March 2024: Clinical and Experimental Rheumatology
https://read.qxmd.com/read/38545742/correction-to-tlr8-aggravates-skin-inflammation-and-fibrosis-by-activating-skin-fibroblasts-in-systemic-sclerosis
#8
(no author information available yet)
No abstract text is available yet for this article.
March 27, 2024: Rheumatology
https://read.qxmd.com/read/38545738/correction-to-efficacy-and-management-of-tocilizumab-in-polymyalgia-rheumatica-results-of-a-multicentre-retrospective-observational-study
#9
(no author information available yet)
No abstract text is available yet for this article.
March 27, 2024: Rheumatology
https://read.qxmd.com/read/38545545/different-biologics-for-biological-na%C3%A3-ve-patients-with-psoriatic-arthritis-a-systematic-review-and-network-meta-analysis
#10
Jixia Lin, Yougang Ren
Aim: To systematically compare the efficacy and safety of biologics [tumor necrosis factor inhibitors (TNFi), interleukin (IL) inhibitors, phosphodiesterase-4 inhibitors (PDE4i), and Janus kinase inhibitors (JAKi)] for biological-naïve patients with psoriatic arthritis (PsA). Methods: PubMed, Web of Science, Embase, and Cochrane Library were comprehensively searched until 12 March 2023. Only head-to-head active comparison studies were included, and placebo-controlled studies without active biologic comparators were excluded...
2024: Frontiers in Pharmacology
https://read.qxmd.com/read/38544289/title-sarcopenia-assessed-by-dxa-and-hand-grip-dynamometer-a-potential-marker-of-damage-disability-and-myokines-imbalance-in-inflammatory-myopathies
#11
JOURNAL ARTICLE
Margherita Giannini, Anne-Laure Charles, Charles Evrard, Julien Blaess, Maude Bouchard-Marmen, Léa Debrut, Simone Perniola, Gilles Laverny, Rose-Marie Javier, Anne Charloux, Bernard Geny, Alain Meyer
OBJECTIVES: To assess the ability of dual-energy X-ray absorptiometry (DXA) and hand-grip dynamometer to measure damage in inflammatory myopathies (IM). METHODS: . Forty adult IM patients with a disease duration ≥12 months, low or no disease activity for ≥6 months, were prospectively enrolled. Thirty healthy age and sex-matched volunteers were enrolled as controls. Whole-body DXA and hand-grip dynamometer were used to measure muscle mass, grip strength and diagnose sarcopenia (EWGSOP2 criteria)...
March 27, 2024: Rheumatology
https://read.qxmd.com/read/38542045/real-life-comparison-of-four-jak-inhibitors-in-rheumatoid-arthritis-electra-i-study
#12
JOURNAL ARTICLE
Maurizio Benucci, Francesca Li Gobbi, Arianna Damiani, Edda Russo, Serena Guiducci, Mariangela Manfredi, Barbara Lari, Valentina Grossi, Maria Infantino
Background: Real-world evidence of the efficacy and adverse events of JAK inhibitor treatment (Tofacitinib, Baricitinib, Upadacitinib, and Filgotinib) in rheumatoid arthritis is still limited. Methods: We studied 115 patients from the Rheumatology Unit of S. Giovanni di Dio Hospital affected by D2T-RA, according to the 2010 EULAR criteria. Out of the 115 patients, 17 had been treated with Baricitinib 8 mg/daily, 32 with Filgotinib 200 mg/daily, 21 with Tofacitinib 10 mg/daily, and 45 with Upadacitinib 15 mg/daily...
March 21, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38542031/current-and-future-challenges-for-rehabilitation-for-inflammatory-arthritis
#13
REVIEW
Rikke Helene Moe, Thea P M Vliet Vlieland
This narrative review discusses the importance of rehabilitation in rheumatic and musculoskeletal diseases (RMDs), ultimately aiming to reduce their impact on individuals and society. It specifically emphasizes the need for rehabilitation in inflammatory arthritis (IA), particularly in cases where medical management is insufficient. It acknowledges that the complexity of rehabilitation demands a flexible approach. Thereby, it touches on the various models of rehabilitation, which may include multidisciplinary team care, extended practice models, shared care, remote care, and work rehabilitation...
March 21, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38540977/a-multidisciplinary-approach-to-the-management-of-eales-disease-a-case-report-and-review-of-the-literature
#14
Maria Filoftea Mercuț, Oana Maria Ică, Cornelia Andreea Tănasie, Răzvan Mercuț, Carmen Luminița Mocanu, Andreea Mihaela Nicolcescu, Ciprian Danielescu
Eales disease manifests as an obliterative periphlebitis affecting the retina; it originates from the periphery and progresses posteriorly. It is characterized by retinal vessel wall inflammation, ischemia, and retinal neovascularization. In this report, we present the case of a 34-year-old male who attended our clinic with a sudden blurring of vision in his right eye. A diagnosis of bilateral retinal vasculitis with vitreal hemorrhage was ascertained in his RE. A dilated ocular fundus examination revealed perivenous sheathing of the peripheral vessels in both eyes...
February 22, 2024: Journal of Personalized Medicine
https://read.qxmd.com/read/38538951/pharmacological-interventions-for-early-stage-frozen-shoulder-a-systematic-review-and-network-meta-analysis
#15
JOURNAL ARTICLE
Juan Enrique Berner, Marios Nicolaides, Stephen Ali, Georgios Pafitanis, Jane Preece, Sally Hopewell, Jagdeep Nanchahal
OBJECTIVES: To evaluate the efficacy of pharmacological interventions for treating early-stage, pain predominant, adhesive capsulitis, also known as frozen shoulder. METHODS: We performed a systematic review in accordance with PRSIMA guidelines. Searches were conducted on PUBMED, EMBASE and Cochrane Central Register of Controlled Trials on the 24th of February 2022. Outcomes were shoulder pain, shoulder function and range of movement. Synthesis involved both qualitative analysis for all studies and pairwise meta-analyses followed by a network meta-analysis for randomised controlled trials (RCTs)...
March 27, 2024: Rheumatology
https://read.qxmd.com/read/38538907/the-value-of-mri-based-radiomics-for-evaluating-early-parotid-gland-injury-in-primary-sj%C3%A3-gren-s-syndrome
#16
JOURNAL ARTICLE
Lu Lu, Tiantian Dai, Yi Zhao, Hang Qu, Qi An Sun, Hongyi Xia, Wei Wang, Guoqing Li
OBJECTIVE: This study aimed to evaluate the value of machine learning models (ML) based on MRI radiomics in diagnosing early parotid gland injury in primary Sjögren's syndrome (pSS). METHODS: A total of 164 patients (114 in the training cohort and 50 in the testing cohort) with pSS (n=82) or healthy controls (HC) (n=82) were enrolled. Itksnap software was used to perform two-dimensional segmentation of the bilateral parotid glands on T1-weighted (T1WI) and fat-suppressed T2-weighted imaging (fs-T2WI) images...
March 27, 2024: Clinical Rheumatology
https://read.qxmd.com/read/38538884/histopathological-comparison-of-sj%C3%A3-gren-related-features-between-paired-labial-and-parotid-salivary-gland-biopsies-of-sicca-patients
#17
JOURNAL ARTICLE
Uzma Nakshbandi, Martha S van Ginkel, Gwenny M P J Verstappen, Fred K L Spijkervet, Suzanne Arends, Erlin A Haacke, Silvia C Liefers, Arjan Vissink, Hendrika Bootsma, Frans G M Kroese, Bert van der Vegt
OBJECTIVES: To compare focus score (FS) and other histopathological features between paired labial and parotid salivary gland biopsies in a diagnostic cohort of suspected Sjögren's disease (SjD) patients. METHODS: Labial and parotid salivary gland biopsies were simultaneously obtained from patients with sicca complaints, suspected of having SjD. Biopsies were formalin fixed and paraffin embedded. Sections were stained with haematoxylin & eosin (H&E) and for CD3, CD20, CD45, cytokeratin, CD21, Bcl6, activation induced deaminase (AID), and IgA/IgG...
March 27, 2024: Rheumatology
https://read.qxmd.com/read/38538820/urate-lowering-agents-do-not-have-clinically-relevant-negative-effects-on-sperm-quality-and-reproductive-hormones-in-men-with-gout-a-prospective-open-label-cohort-study
#18
JOURNAL ARTICLE
Changhong Li, Yuanyuan Wang, Rong Mu, Jinxia Zhao, Zhongqiang Yao, Jiayu Zhai, Yinji Jin, Rui Liu, Defeng Liu, Kai Hong, Hui Jiang, Zhe Zhang
OBJECTIVE: The objective of this study was to analyze and compare the effects of different urate-lowering agents on testicular functions in men with gout in a clinical setting. METHODS: In this prospective cohort study (Clinical Trial Registration Number: NCT04213534), a total of 49 male patients aged 18-45 years with gout were enrolled. They were divided into three groups and received treatment with either allopurinol, febuxostat or benzbromarone for a duration of 3 months...
March 27, 2024: Rheumatology International
https://read.qxmd.com/read/38538764/diagnosis-of-large-vessel-vasculitis-in-the-community-a-specific-benefit-from-a-non-specific-symptom-pathway
#19
JOURNAL ARTICLE
Russel Machin, Tom Sulkin, Giles Maskell, Mark Hughes
No abstract text is available yet for this article.
March 27, 2024: Rheumatology
https://read.qxmd.com/read/38538758/low-frequency-and-rare-genetic-variants-associated-with-rheumatoid-arthritis-risk
#20
REVIEW
Vanessa L Kronzer, Jeffrey A Sparks, Soumya Raychaudhuri, James R Cerhan
Rheumatoid arthritis (RA) has an estimated heritability of nearly 50%, which is particularly high in seropositive RA. HLA alleles account for a large proportion of this heritability, in addition to many common single-nucleotide polymorphisms with smaller individual effects. Low-frequency and rare variants, such as those captured by next-generation sequencing, can also have a large role in heritability in some individuals. Rare variant discovery has informed the development of drugs such as inhibitors of PCSK9 and Janus kinases...
March 27, 2024: Nature Reviews. Rheumatology
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