Fengjiao Zhu, Yangyang Long, Weiwei Shi, Bin Li, Yahui Ji, Xue Bai, Xianming Liu, Dongyuan Qi, Bo Sun, Fuyin Zhang, Tingjiao Liu, Bingcheng Lin, Yao Lu
Discriminating secretory phenotypes provides a direct, intact, and dynamic way to evaluate the heterogeneity in cell states and activation, which is significant for dissecting non-genetic heterogeneity for human health studies and disease diagnostics. In particular, secreted microRNAs, soluble signaling molecules released by various cells, are increasingly recognized as a critical mediator for cell-cell communication and the circulating biomarkers for disease diagnosis. However, single-cell analysis of secreted miRNAs is still lacking due to the limited available tools...
April 17, 2024: Biosensors & Bioelectronics