Rodrigo Abensur Athanazio, Suzana Erico Tanni, Juliana Ferreira, Paulo de Tarso Roth Dalcin, Marcelo B de Fuccio, Concetta Esposito, Mariane Gonçalves Martynychen Canan, Liana Sousa Coelho, Mônica de Cássia Firmida, Marina Buarque de Almeida, Paulo José Cauduro Marostica, Luciana de Freitas Velloso Monte, Edna Lúcia Souza, Leonardo Araujo Pinto, Samia Zahi Rached, Verônica Stasiak Bednarczuk de Oliveira, Carlos Antonio Riedi, Luiz Vicente Ribeiro Ferreira da Silva Filho
Cystic fibrosis (CF) is a genetic disease that results in dysfunction of the CF transmembrane conductance regulator (CFTR) protein, which is a chloride and bicarbonate channel expressed in the apical portion of epithelial cells of various organs. Dysfunction of that protein results in diverse clinical manifestations, primarily involving the respiratory and gastrointestinal systems, impairing quality of life and reducing life expectancy. Although CF is still an incurable pathology, the therapeutic and prognostic perspectives are now totally different and much more favorable...
2023: Jornal Brasileiro de Pneumologia: Publicaça̋o Oficial da Sociedade Brasileira de Pneumologia e Tisilogia