Aynur Akin, Adnan Bayram, Aliye Esmaoglu, Zeynep Tosun, Recep Aksu, Resul Altuntas, Adem Boyaci
BACKGROUND: Dexmedetomidine, an α(2)-receptor agonist, provides sedation, analgesia, and anxiolytic effects, and these properties make it a potentially useful anesthetic premedication. In this study, we compared the effects of intranasal dexmedetomidine and midazolam on mask induction and preoperative sedation in pediatric patients. METHODS: Ninety children classified as ASA physical status I, aged between 2 and 9, who were scheduled to undergo an elective adenotonsillectomy, were enrolled for a prospective, randomized, and double-blind controlled trial...
September 2012: Paediatric Anaesthesia