Taku Inohara, Toshiaki Otsuka, Yusuke Watanabe, Shinichi Shirai, Norio Tada, Futoshi Yamanaka, Hiroshi Ueno, Yohei Ohno, Minoru Tabata, Hiroto Suzuyama, Masahiko Asami, Masahiro Yamawaki, Masaki Izumo, Kazumasa Yamasaki, Hidetaka Nishina, Yasushi Fuku, Kazuki Mizutani, Fumiaki Yashima, Masanori Yamamoto, Kentaro Hayashida
BACKGROUND: Despite the wide implementation of transcatheter aortic valve implantation (TAVI), the optimal antithrombotic therapy after TAVI has not been established yet. Owing to the accumulating evidence supporting the efficacy and safety of single antiplatelet therapy (SAPT) over dual antiplatelet therapy, the latest guideline recommends life-long SAPT. However, there is scarce evidence supporting SAPT compared with non-antithrombotic therapy. Given the vulnerability of patients undergoing TAVI in terms of high bleeding risk, the benefit of SAPT may be canceled out by its potential increased bleeding risk...
October 16, 2023: Contemporary Clinical Trials