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JOURNAL ARTICLE
V T Vaiciurgis, A Clancy, K E Charlton, A Stefoska-Needham, E J Beck
OBJECTIVE: Diet quality is significantly impacted by social and environmental factors. People experiencing socioeconomic disadvantage face inequitable barriers to accessing nutritious foods and health services, resulting in significant health disparities. This study aimed to explore the barriers faced by organisations that provide food support to people experiencing disadvantage as well as to identify potential strategies to enhance this support for improved wellbeing of clients. DESIGN: Semi-structured interviews using an exploratory approach and inductive thematic analysis...
January 15, 2024: Public Health Nutrition
#62
JOURNAL ARTICLE
Consumer acceptance and quality of game meat "droëwors" sausages with different levels of added fat.
Daniel Bureš, Tersia Needham, Luděk Bartoň, Nicole Lebedová, Radim Kotrba, Dalibor Řehák, Iva Kučerová, Pavel Klouček, Louwrens C Hoffman
Droëwors (dried sausage) is a unique dried meat product from South Africa, which is not smoked, fermented, nor is nitrite used in its production. The objective of the study was to compare the quality parameters and consumer acceptance of common eland meat droëwors with different quantities of added beef fat. Three treatments containing either 10, 15, or 20% (by weight) added beef fat were compared regarding chemical composition, fatty acid profiles, and sensory properties. Increasing the amount of fat in the dried product resulted in a significant decrease in the protein and ash percentages...
January 3, 2024: Meat Science
#63
JOURNAL ARTICLE
Didem Saygin, Victoria Werth, Julie J Paik, Jin Kyun Park, Merrilee Needham, Ingrid E Lundberg, Lisa Christopher-Stine
With improved understanding of disease pathogenesis and availability of outcome measures, there has been a remarkable increase in the number of therapeutic clinical trials in idiopathic inflammatory myopathies (myositis) over the last three years reaching as many as five trials per site. These trials share similar design and inclusion/exclusion criteria resulting in a competitive clinical trial landscape in myositis. While these are exciting times for the myositis field, we have a number of concerns about the design and conduct of the myositis trials...
January 12, 2024: Annals of the Rheumatic Diseases
#64
JOURNAL ARTICLE
Christopher L Chapman, Sadie M Holt, Cameron T O'Connell, Shaun C Brazelton, Hannah N Medved, William A B Howells, Emma L Reed, Karen Wiedenfeld Needham, John R Halliwill, Christopher T Minson
Insufficient hydration is prevalent amongst free living adults. This study investigated whether hypohydration alters 1) renal functional reserve, 2) the renal hemodynamic response to the exercise pressor reflex, and 3) urine concentrating ability during oral protein loading. In a block-randomized crossover design, 22 healthy young adults (11 females and 11 males) underwent 24 h fluid deprivation (Hypohydrated) or 24 h normal fluid consumption (Euhydrated). Renal functional reserve was assessed by oral protein loading...
January 11, 2024: Journal of Applied Physiology
#65
JOURNAL ARTICLE
Thoniso Chitambala, Veit Ny, Francisco Ceacero, Luděk Bartoň, Daniel Bureš, Radim Kotrba, Tersia Needham
Forty-four fallow deer bucks (10 months old; 22.9 ± 2.4 kg) were utilized to investigate the effects of immunocastration and amino acid supplementation on testes development. Immunocastrated bucks were administered Improvac® at weeks 1, 8, and 20 of this study (control group: intact males). Starting at week 8, half of each sex received rumen-protected lysine and methionine (3:1) supplementation. At slaughter (week 37/39), body size, internal fat deposits, antler size parameters, testes weight, testes surface color, cauda epididymal sperm viability and morphology, and seminiferous tubule circumference and epithelium thickness were determined...
December 28, 2023: Animals: An Open Access Journal From MDPI
#66
Belinda Yau, Sheyda Naghiloo, Alexis Diaz-Vegas, Austin V Carr, Julian Van Gerwen, Elise J Needham, Dillon Jevon, Sing-Young Chen, Kyle L Hoehn, Amanda E Brandon, Laurence Macia, Gregory J Cooney, Michael R Shortreed, Lloyd M Smith, Mark P Keller, Peter Thorn, Mark Larance, David E James, Sean J Humphrey, Melkam A Kebede
[This corrects the article DOI: 10.1016/j.isci.2021.103099.].
January 19, 2024: IScience
#67
JOURNAL ARTICLE
D Saygin, D DiRenzo, J Raaphorst, I de Groot, C O Bingham, I E Lundberg, M Regardt, C Sarver, M de Visser, L J Maxwell, D Beaton, J Y Kim, M Needham, H Alexanderson, L Christopher-Stine, C A Mecoli, J K Park
BACKGROUND: A series of qualitative studies conducted by the OMERACT Myositis Working Group identified pain interference, fatigue, and physical function as highly important life impact domains for adults with idiopathic inflammatory myositis (IIM). In this study, our goal was to assess the responsiveness and minimal important difference of PROMIS pain interference (6a), fatigue (7a), and physical function (8b). METHODS: Adults with IIM from USA, Netherlands, Korea, Sweden, and Australia with two "clinical" visits were enrolled in this prospective study...
December 9, 2023: Seminars in Arthritis and Rheumatism
#68
JOURNAL ARTICLE
Sieun Ju, Yohan Park
A paradigm that combines cloud computing and the Internet of Things (IoT) allows for more impressive services to be provided to users while addressing storage and computational resource issues in the IoT environments. This cloud-based IoT environment has been used in various industries, including public services, for quite some time, and has been researched in academia. However, various security issues can arise during the communication between IoT devices and cloud servers, because communication between devices occurs in open channels...
December 11, 2023: Sensors
#69
JOURNAL ARTICLE
Benedict D Michael, Cordelia Dunai, Edward J Needham, Kukatharmini Tharmaratnam, Robyn Williams, Yun Huang, Sarah A Boardman, Jordan J Clark, Parul Sharma, Krishanthi Subramaniam, Greta K Wood, Ceryce Collie, Richard Digby, Alexander Ren, Emma Norton, Maya Leibowitz, Soraya Ebrahimi, Andrew Fower, Hannah Fox, Esteban Tato, Mark A Ellul, Geraint Sunderland, Marie Held, Claire Hetherington, Franklyn N Egbe, Alish Palmos, Kathy Stirrups, Alexander Grundmann, Anne-Cecile Chiollaz, Jean-Charles Sanchez, James P Stewart, Michael Griffiths, Tom Solomon, Gerome Breen, Alasdair J Coles, Nathalie Kingston, John R Bradley, Patrick F Chinnery, Jonathan Cavanagh, Sarosh R Irani, Angela Vincent, J Kenneth Baillie, Peter J Openshaw, Malcolm G Semple, Leonie S Taams, David K Menon
To understand neurological complications of COVID-19 better both acutely and for recovery, we measured markers of brain injury, inflammatory mediators, and autoantibodies in 203 hospitalised participants; 111 with acute sera (1-11 days post-admission) and 92 convalescent sera (56 with COVID-19-associated neurological diagnoses). Here we show that compared to 60 uninfected controls, tTau, GFAP, NfL, and UCH-L1 are increased with COVID-19 infection at acute timepoints and NfL and GFAP are significantly higher in participants with neurological complications...
December 22, 2023: Nature Communications
#70
JOURNAL ARTICLE
Martin B Brodsky, Lisa Aronson Friedman, Elizabeth Colantuoni, Vinciya Pandian, Anne E Vertigan, Dale M Needham, Kitty S Chan
BACKGROUND: The Newcastle Laryngeal Hypersensitivity Questionnaire (LHQ) was developed to measure abnormal laryngeal sensation and was originally validated in a patient sample from otolaryngologic and respiratory outpatient clinics. Modification is needed for patients who are mechanically ventilated via an endotracheal tube or a tracheostomy tube. OBJECTIVES: We sought to adapt and preliminarily validate a modified version of the LHQ appropriate for nurses and other clinicians to administer in acute hospital settings called the LHQ-Acute (LHQ-A)...
December 21, 2023: Australian Critical Care: Official Journal of the Confederation of Australian Critical Care Nurses
#71
JOURNAL ARTICLE
Katherine Tubby, Jack Forster, Martin Mullett, Robert Needham, Olivia Smith, James Snowden, Shelagh McCartan
The international plant trade results in the accidental movement of invasive pests and pathogens, and has contributed significantly to recent range expansion of pathogens including Dothistroma septosporum. Seeds are usually thought to present a lower biosecurity risk than plants, but the importation of Pinus contorta seeds from North America to Britain in the mid-1900s, and similarities between British and Canadian D. septosporum populations suggests seeds could be a pathway. Dothistroma septosporum has not been isolated from seeds, but inadequately cleaned seed material could contain infected needle fragments...
December 13, 2023: Journal of Fungi (Basel, Switzerland)
#72
JOURNAL ARTICLE
Anita Stefoska-Needham, Christopher M Weber, Eleanor J Beck, Joel C Craddock, Lauren A Houston
AIM: Male dietitians are under-represented in the global dietetics workforce, including in Australia. This study explores Australian males' experiences as dietitians in the Australian workforce, with the aim to identify influences that initially attracted them to dietetics, as well as barriers that may affect their decision to stay in or leave the profession. METHODS: A cross-sectional, semi-quantitative web-based survey was distributed to male dietitians using purposive, snowball sampling...
December 19, 2023: Nutrition & Dietetics: the Journal of the Dietitians Association of Australia
#73
S Basu, O Shukron, D Hall, P Parutto, A Ponjavic, D Shah, W Boucher, D Lando, W Zhang, N Reynolds, L H Sober, A Jartseva, R Ragheb, X Ma, J Cramard, R Floyd, J Balmer, T A Drury, A R Carr, L-M Needham, A Aubert, G Communie, K Gor, M Steindel, L Morey, E Blanco, T Bartke, L Di Croce, I Berger, C Schaffitzel, S F Lee, T J Stevens, D Klenerman, B D Hendrich, D Holcman, E D Laue
No abstract text is available yet for this article.
December 15, 2023: Nature Structural & Molecular Biology
#74
JOURNAL ARTICLE
Nikita Wheaton, Emily Alston, Vincent L Versace, Michael Field, Anna Wong Shee, Jane Jacobs, Kathryn Backholer, Steven Allender, Melanie Nichols, Cindy Needham, Kristy A Bolton, Miranda R Blake, Fletcher Stewart, Evelyn Close, Laura Alston
Bold and comprehensive action is needed to prevent diet-related diseases in rural areas, which includes improving food environments to enable healthier dietary practices. Rural health services are integral to the health of rural populations, yet their role in community disease prevention is not swell understood. This study sought to understand health service, local government, and food outlet stakeholders' perspectives on (1) the drivers of unhealthy retail environments in a rural setting; (2) the role of rural health services in supporting changes in local food environments; and to (3) identify characteristics of potential interventions...
November 30, 2023: Nutrients
#75
JOURNAL ARTICLE
Seema Chopra, Sarah Needham-Beck, Jatin P Ambegaonkar
Introduction: Dance is physically demanding and results in blood lactate (BL) accumulation and elevated Heart Rate (HR). Researchers recommend using either Active Recovery (AR; eg, low-to-moderate intensity-exercise) or Passive Recovery (PR; eg, complete rest) modes after activity. We compared BL and HR responses between AR or PR over a 15-minute recovery period following a Kathak dance. Methods: Twelve female dancers (31.0 ± 6.0 years; 161.5 ± 4.9 cm; 55...
December 3, 2023: Journal of Dance Medicine & Science
#76
JOURNAL ARTICLE
Nataliya Slater, Anuradha Sooda, Emily McLeish, Kelly Beer, Anna Brusch, Rakesh Shakya, Christine Bundell, Ian James, Abha Chopra, Frank L Mastaglia, Merrilee Needham, Jerome D Coudert
OBJECTIVES: Inclusion body myositis (IBM) is a progressive inflammatory-degenerative muscle disease of older individuals, with some patients producing anti-cytosolic 5'-nucleotidase 1A (NT5C1A, aka cN1A) antibodies. Human Leukocyte Antigens (HLA) is the highest genetic risk factor for developing IBM. In this study, we aimed to further define the contribution of HLA alleles to IBM and the production of anti-cN1A antibodies. METHODS: We HLA haplotyped a Western Australian cohort of 113 Caucasian IBM patients and 112 ethnically matched controls using Illumina next-generation sequencing...
December 2, 2023: Journal of Autoimmunity
#77
JOURNAL ARTICLE
Ying Zhou, Nadia Chandra Sekar, Peter Thurgood, Scott Needham, Karlheinz Peter, Khashayar Khoshmanesh, Sara Baratchi
Foam cell formation is a complex blood vessel pathology, which is characterized by a series of events, including endothelium dysfunction, inflammation, and accumulation of immune cells underneath the blood vessel walls. Novel bioengineered models capable of recapitulating these events are required to better understand the complex pathological processes underlying the development of foam cell formation and, consequently, advanced bioengineered platforms for screening drugs. Here, we generated a microfluidic blood vessel model, incorporating a three-dimensional (3D) extracellular matrix coated with an endothelial layer...
November 29, 2023: ACS Biomaterials Science & Engineering
#78
JOURNAL ARTICLE
Benjamin Littenberg, Jessica Clifton, Abigail M Crocker, Laura-Mae Baldwin, Levi N Bonnell, Ryan E Breshears, Peter Callas, Prama Chakravarti, Kelly Clark/Keefe, Deborah J Cohen, Frank V deGruy, Lauren Eidt-Pearson, William Elder, Chester Fox, Sylvie Frisbie, Katie Hekman, Juvena Hitt, Jennifer Jewiss, David C Kaelber, Kairn Stetler Kelley, Rodger Kessler, Jennifer B O'Rourke-Lavoie, George S Leibowitz, C R Macchi, Matthew P Martin, Mark McGovern, Brenda Mollis, Daniel Mullin, Zsolt Nagykaldi, Lisa W Natkin, Wilson Pace, Richard G Pinckney, Douglas Pomeroy, Paula Reynolds, Gail L Rose, Sarah Hudson Scholle, William J Sieber, Jeni Soucie, Terry Stancin, Kurt C Stange, Kari A Stephens, Kathryn Teng, Elizabeth Needham Waddell, Constance van Eeghen
PURPOSE: Patient outcomes can improve when primary care and behavioral health providers use a collaborative system of care, but integrating these services is difficult. We tested the effectiveness of a practice intervention for improving patient outcomes by enhancing integrated behavioral health (IBH) activities. METHODS: We conducted a pragmatic, cluster randomized controlled trial. The intervention combined practice redesign, quality improvement coaching, provider and staff education, and collaborative learning...
2023: Annals of Family Medicine
#79
JOURNAL ARTICLE
T W Davies, E Kelly, R J J van Gassel, M C G van de Poll, J Gunst, M P Casaer, K B Christopher, J C Preiser, A Hill, K Gundogan, A Reintam-Blaser, A-F Rousseau, C Hodgson, D M Needham, S J Schaller, T McClelland, J J Pilkington, C M Sevin, P E Wischmeyer, Z Y Lee, D Govil, L Chapple, L Denehy, J C Montejo-González, B Taylor, D E Bear, R M Pearse, A McNelly, J Prowle, Z A Puthucheary
BACKGROUND: CONCISE is an internationally agreed minimum set of outcomes for use in nutritional and metabolic clinical research in critically ill adults. Clinicians and researchers need to be aware of the clinimetric properties of these instruments and understand any limitations to ensure valid and reliable research. This systematic review and meta-analysis were undertaken to evaluate the clinimetric properties of the measurement instruments identified in CONCISE. METHODS: Four electronic databases were searched from inception to December 2022 (MEDLINE via Ovid, EMBASE via Ovid, CINAHL via Healthcare Databases Advanced Search, CENTRAL via Cochrane)...
November 20, 2023: Critical Care: the Official Journal of the Critical Care Forum
#80
JOURNAL ARTICLE
Suthee Wiri, Christina Wagner, Jasmyne Longwell, Tasha Adams, Joshua Whitty, Todd Massow, James Reid, Cyrus Dunbar, Wallace Graves, Andrea Gonzales, Charles E Needham, Fabio Leonessa, Josh L Duckworth
INTRODUCTION: During training and deployment, service members (SMs) experience blast exposure, which may potentially negatively impact brain health in the short and long term. This article explores if blast exposure mitigation can be effectively achieved for four different weapon training scenarios that are being monitored as part of the CONQUER (COmbat and traiNing QUeryable Exposure/event Repository) program. The training scenarios considered here are a detonating cord linear (det linear) breaching charge, a water breaching charge, a shoulder-fired weapon, and a 120-mm mortar...
November 7, 2023: Military Medicine
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