Di Liu, Si-Yuan Huang, Jian-Hui Sun, Hua-Cai Zhang, Qing-Li Cai, Chu Gao, Li Li, Ju Cao, Fang Xu, Yong Zhou, Cha-Xiang Guan, Sheng-Wei Jin, Jin Deng, Xiang-Ming Fang, Jian-Xin Jiang, Ling Zeng
Sepsis is a common complication of combat injuries and trauma, and is defined as a life-threatening organ dysfunction caused by a dysregulated host response to infection. It is also one of the significant causes of death and increased health care costs in modern intensive care units. The use of antibiotics, fluid resuscitation, and organ support therapy have limited prognostic impact in patients with sepsis. Although its pathophysiology remains elusive, immunosuppression is now recognized as one of the major causes of septic death...
October 9, 2022: Military Medical Research