Ines Matoc, Kim Kasa, Armin Kasumović, Ante Prpić, Ante Vukojević, Ognjen Zrinšćak, Jelena Škunca Herman, Blanka Doko Mandić, Ivan Sabol, Renata Iveković, Zoran Vatavuk
The aim of this study is to assess the effectiveness of a 12-week doxycycline treatment for thyroid eye disease (TED), an autoimmune condition associated with thyroid dysfunction. In this randomized controlled clinical trial, 82 patients were randomly assigned at a 1:1 ratio to receive doxycycline (50 mg) or to undergo no treatment. Various metrics, including margin reflex distance (MRD1 and MRD2), eyelid aperture, levator muscle function, lagophthalmos, proptosis, ocular motility, diplopia, and Graves' ophthalmopathy-specific quality-of-life (GO-QOL) scale scoring were assessed...
April 10, 2024: Diagnostics