Minglan Wu, Qi Wang, Xiaodong Li, Songxia Yu, Fan Zhao, Xia Wu, Li Fan, Xueling Liu, Qingwei Zhao, Xuelin He, Weifen Li, Qiao Zhang, Xingjiang Hu
Polysaccharides from Pumpkin (Cucurbita moschata Duchesne) (PPs) have many pharmacological activities, including anti-oxidant, immune, and intestinal microbiota regulation. These activities have provided some reminders of its potential therapeutic effect on ulcerative colitis (UC), but this has not yet been confirmed. This study preliminarily confirmed its significant anti-UC activity superior to Salicylazosulfapyridine. The average molecular weight of PPs was 3.10 × 105 Da, and PPs mainly comprised Mannose, Rhamnose, Galacturonic acid, Galactosamine, Glucose, and Xylose with molar ratios of 1...
February 21, 2024: International Journal of Biological Macromolecules