Florence Fischer, Tobias Kretschmer, Paulina Seifert, Julia Howanski, Elisabeth Krieger, Jonas Rödiger, Beate Fink, Ziran Yin, Mario Bauer, María Laura Zenclussen, Nicole Meyer, Anne Schumacher, Ana Claudia Zenclussen
Endocrine disrupting chemicals (EDCs) possess the capability to interfere with the endocrine system by binding to hormone receptors, for example on immune cells. Specific effects have already been described for individual substances, but the impact of exposure to chemical mixtures during pregnancy on maternal immune regulation, placentation and fetal development is not known. In this study, we aimed to investigate the combined effects of two widespread EDCs bisphenol A (BPA) and benzophenone-3 (BP-3) at allowed concentrations on crucial pregnancy processes such as implantation, placentation, uterine immune cell populations and fetal growth...
February 29, 2024: Science of the Total Environment