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JOURNAL ARTICLE
Sumin Hong, Eun Jung Cha, Yeonsil Moon, Seung-Ho Ryu, Hong Jun Jeon
OBJECTIVE: It has been reported that depressive symptoms in older adults are different from those in younger adults, especially when accompanied by cognitive decline. However, few studies have investigated the network structure of depressive symptoms in this population. METHODS: The participants consisted of 627 older adults (>60 yr) who were diagnosed with mild cognitive impairment (MCI) or early stage dementia. Among them, 36.7% were male and the mean age was 76...
April 2024: Psychiatry Investigation
#42
JOURNAL ARTICLE
Junjing Wang, Qian Liang, An Yang, Yueqi Ma, Yi Zhang
OBJECTIVE: Although previous studies have validated the effect of childhood trauma on depressive level, few studies have utilized the diathesis-stress theory to investigate the specific roles of perceived stress and rumination in the pathway between childhood trauma and depression in Chinese college students. This study aims to demonstrate the mediation effect of perceived stress and the moderation effect of rumination in the pathway between childhood trauma and depressive level in Chinese college students...
April 2024: Psychiatry Investigation
#43
JOURNAL ARTICLE
Chen Geng, Miao Zhang, Lily Zhang, Hai Yin, Suyun Wang
OBJECTIVE: Narrative exposure therapy (NET) has been used in various contexts for the treatment of the effects of trauma, with promising results in clinical trials. However, its effects on anxiety and depression are still unclear. The present study is a systematic review and meta-analysis of the effects of NET on depression and anxiety. METHODS: The Embase, Cumulative Index of Nursing and Allied Health Literature, PubMed, Web of Science core collection, Cochrane Library, Chinese National Knowledge Infrastructure, Chinese Biomedical Database, and Wangfang databases were searched from the earliest records to March 2023...
April 2024: Psychiatry Investigation
#44
JOURNAL ARTICLE
Kanyada Leelasittikul, Apiwat Pugongchai, Chatkarin Tepwimonpetkun, Narongkorn Saiphoklang
BACKGROUND: This study is aimed at determining the quality of life, mental health, and adherence to continuous positive airway pressure (CPAP) therapy for obstructive sleep apnea (OSA) among Thai OSA patients during the coronavirus disease 2019 (COVID-19) pandemic as this data has been lacking. METHODS: A cross-sectional study was conducted at a university hospital between September 2021 and April 2022. OSA patients aged 18 years or older who required home CPAP treatment were included...
2024: Sleep Disorders
#45
JOURNAL ARTICLE
Tina R Goldstein, John Merranko, Danella Hafeman, Mary Kay Gill, Fangzi Liao, Craig Sewall, Heather Hower, Lauren Weinstock, Shirley Yen, Benjamin Goldstein, Martin Keller, Michael Strober, Neal Ryan, Boris Birmaher
OBJECTIVES: To build a one-year risk calculator (RC) to predict individualized risk for suicide attempt in early-onset bipolar disorder. METHODS: Youth numbering 394 with bipolar disorder who completed ≥2 follow-up assessments (median follow-up length = 13.1 years) in the longitudinal Course and Outcome of Bipolar Youth (COBY) study were included. Suicide attempt over follow-up was assessed via the A-LIFE Self-Injurious/Suicidal Behavior scale. Predictors from the literature on suicidal behavior in bipolar disorder that are readily assessed in clinical practice were selected and trichotomized as appropriate (presence past 6 months/lifetime history only/no lifetime history)...
October 2023: Focus: Journal of Life Long Learning in Psychiatry
#46
JOURNAL ARTICLE
Lori L Altshuler, Trisha Suppes, David O Black, Willem A Nolen, Gabriele Leverich, Paul E Keck, Mark A Frye, Ralph Kupka, Susan L McElroy, Heinz Grunze, Christina M R Kitchen, Robert Post
OBJECTIVES: The authors compared the switch rate into hypomania/mania in depressed patients treated with second-generation antidepressants who had either bipolar I or bipolar II disorder. METHODS: In a 10-week trial, 184 outpatients with bipolar depression (134 with bipolar I disorder, 48 with bipolar II disorder, two with bipolar disorder not otherwise specified) were treated with one of three antidepressants as an adjunct to mood stabilizers. The patients' switch rates were assessed...
October 2023: Focus: Journal of Life Long Learning in Psychiatry
#47
JOURNAL ARTICLE
Leonardo Tondo, Gustavo H Vázquez, Ross J Baldessarini
BACKGROUND: Excess mortality is a critical hallmark of bipolar disorder (BD) due to co-occurring general medical disorders and especially from suicide. It is timely to review of the status of suicide in BD and to consider the possibility of limiting suicidal risk. METHODS: We carried out a semi-systematic review of recent research reports pertaining to suicide in BD. FINDINGS: Suicide risk in BD is greater than with most other psychiatric disorders...
October 2023: Focus: Journal of Life Long Learning in Psychiatry
#48
JOURNAL ARTICLE
Nemanja Ljubic, Bianca Ueberberg, Heinz Grunze, Hans-Jörg Assion
BACKGROUND: Old age bipolar disorder has been an orphan of psychiatric research for a long time despite the fact that bipolar disorder (BD)-I and II together may affect 0.5-1.0% of the elderly. It is also unclear whether aetiology, course of illness and treatment should differ in patients with a first manifestation in older age and patients suffering from a recurrence of a BD known for decades. This narrative review will summarize the current state of knowledge about the epidemiology, clinical features, and treatment of BD in the elderly...
October 2023: Focus: Journal of Life Long Learning in Psychiatry
#49
JOURNAL ARTICLE
Farhan Fancy, Nelson B Rodrigues, Joshua D Di Vincenzo, Edmond H Chau, Rickinder Sethi, Muhammad I Husain, Hartej Gill, Aniqa Tabassum, Andrea Mckenzie, Lee Phan, Roger S McIntyre, Joshua D Rosenblat
BACKGROUND: Clinical trials have demonstrated rapid antidepressant effects with intravenous (IV) ketamine for major depressive disorder, with relatively less research specifically for bipolar depression. Herein, we describe the real-world effectiveness of repeated ketamine infusions for treatment-resistant bipolar depression. METHODS: This study was conducted in a community clinic in Mississauga, Ontario (Canadian Rapid Treatment Centre of Excellence; Braxia Health)...
October 2023: Focus: Journal of Life Long Learning in Psychiatry
#50
REVIEW
Holly A Swartz, Trisha Suppes
Despite its inclusion as a distinct entity in APA's Diagnostic and Statistical Manual of Mental Disorders since 1994, bipolar II disorder remains a surprisingly neglected psychiatric condition. Understudied and underrecognized, bipolar II disorder is often misdiagnosed and misunderstood, even by experienced clinicians. As a result, patients typically experience symptoms for more than 10 years before receiving the correct diagnosis. Incorrect diagnosis leads to incorrect treatment, including overuse of monoaminergic antidepressant medications, with resultant declines in functioning and worse quality of life...
October 2023: Focus: Journal of Life Long Learning in Psychiatry
#51
JOURNAL ARTICLE
Katherine E Burdick, Caitlin E Millett, Anastasia K Yocum, Cara M Altimus, Ole A Andreassen, Valerie Aubin, Raoul Belzeaux, Michael Berk, Joanna M Biernacka, Hilary P Blumberg, Anthony J Cleare, Claudia Diaz-Byrd, Caroline Dubertret, Bruno Etain, Lisa T Eyler, Brent P Forester, Janice M Fullerton, Mark A Frye, Sébastien Gard, Ophelia Godin, Emmanuel Haffen, Federica Klaus, Trine Vik Lagerberg, Marion Leboyer, Anabel Martinez-Aran, Susan McElroy, Philip B Mitchell, Emilie Olie, Phebe Olorunfemi, Christine Passerieux, Amy T Peters, Daniel L Pham, Mircea Polosan, Julia R Potter, Martha Sajatovic, Ludovic Samalin, Raymund Schwan, Megan Shanahan, Brisa Solé, Rebecca Strawbridge, Amanda L Stuart, Ivan Torres, Torrill Ueland, Eduard Vieta, Lana J Williams, Anna L Wrobel, Lakshmi N Yatham, Allan H Young, Andrew A Nierenberg, Melvin G McInnis
OBJECTIVES: Persistent functional impairment is common in bipolar disorder (BD) and is influenced by a number of demographic, clinical, and cognitive features. The goal of this project was to estimate and compare the influence of key factors on community function in multiple cohorts of well-characterized samples of individuals with BD. METHODS: Thirteen cohorts from 7 countries included n = 5882 individuals with BD across multiple sites. The statistical approach consisted of a systematic uniform application of analyses across sites...
October 2023: Focus: Journal of Life Long Learning in Psychiatry
#52
JOURNAL ARTICLE
Li Hao, Arimi Fitri Mat Ludin, Mahadir Ahmad, Xie Meng, He Zhong Lei
UNLABELLED: Psychological issues are of significant concern in present-day society, as poor mental well-being results in depression and suicidal behavior. Understanding the current situation of psychological stress among secondary school students will help policy makers to formulate targeted measures to help them cope with stress, and at the same time evaluate the effectiveness of the existing policies to address the shortcomings and enhance the diversification of interventions. The main purpose of this review was to map the existing evidence on the prevalence and levels of psychological stress among adolescents in China, and to identify the associated risk factors...
2024: Frontiers in Public Health
#53
JOURNAL ARTICLE
Qing Zhang, Ruibo Pan, Qi Pan, Yandan Qian, Xiao Zhou, Qiaozhen Chen
BACKGROUND: Resident physicians at the standardized training stage had undergone significant physical and mental stress during the release of the COVID-19 pandemic restrictions at the end of 2022 in China. This study aimed to investigate the psychological status (including anxiety, depression, somatic symptoms, job burnout, and vicarious trauma) of resident physicians and identify its influencing factors under these special periods. METHODS: Survey was conducted one month after the release of the COVID-19 pandemic restrictions on resident training physicians from a tertiary first-class hospital in Zhejiang, China...
2024: Frontiers in Public Health
#54
MULTICENTER STUDY
Jia-Ning Li, Qing-Xiang Zheng, Xiu-Min Jiang, Xiao-Qian Chen, Ling Huang, Yu-Qing Pan, Ru-Lin Liu, Yu Zhu
BACKGROUND: Shift work can disrupt sleep quality and gut health. Nurses and midwives constitute approximately half of the global healthcare shift-working workforce. Our previous study revealed that most midwives were experiencing suboptimal health conditions, characterized by poor sleep quality and a high prevalence of gastrointestinal diseases. The gut-brain axis theory highlights the potential interplay between sleep quality and gut health. However, limited research focuses on this relationship among midwives...
2024: Frontiers in Public Health
#55
JOURNAL ARTICLE
Heakyong Lee, Jaehee Kim
BACKGROUND: Positive and negative emotions have recently revealed a link with primary dysmenorrhea in adults. Among them, roles of stress and self-esteem have been less studied specially in adolescents and the direction of causality has not been clearly established. Therefore, this study investigated whether stress and self-esteem independently affect primary dysmenorrhea after adjustment for the known risk factors in adolescents. Additionally, indirect effects of stress and self-esteem were determined using mediation analyses...
January 2024: Iranian Journal of Public Health
#56
JOURNAL ARTICLE
Farzana Ashraf, Shahnila Tariq, Rabia Farooqi, Masha Asad Khan, Mark D Griffiths, Faramarz Asanjarani
BACKGROUND: Medical health practitioners, particularly those working in cancer units, are vulnerable to poor psychological outcomes. The present study was designed to examine the influence of workplace bullying on the mental health of medical and paramedical staff by testing workplace burnout as a mediating factor. METHODS: Utilizing a cross-sectional survey, 220 Muslim medical staff officers from the cancer units of three hospitals in Lahore, Pakistan, were assessed for workplace bullying, mental health, and workplace burnout using the standardized psychometric measures (i...
January 2024: Iranian Journal of Public Health
#57
JOURNAL ARTICLE
Rebecca Lewis, Michael D Pointer, Lucy Friend, Matthew J G Gage, Lewis G Spurgin
Small, isolated populations are often characterised by low levels of genetic diversity. This can result in inbreeding depression and reduced capacity to adapt to changes in the environment, and therefore higher risk of extinction. However, sometimes these populations can be rescued if allowed to increase in size or if migrants enter, bringing in new allelic variation and thus increasing genetic diversity. This study uses experimental manipulation of population size and migration to quantify their effects on fitness in a challenging environment to better understand genetic rescue...
May 2024: Ecology and Evolution
#58
Saliha Erdem, Ahmad Damlakhy, Kristin Konja, Sifullah Bashar
Serotonin toxicity, an adverse consequence of elevated serotonin levels in the brain, poses a considerable threat to life. Antidepressants, frequently prescribed for various conditions in older adults, such as depression, anxiety, and sleep disturbances, significantly contribute to this risk. The elderly are particularly vulnerable due to multiple comorbidities, cognitive decline, medication interactions, polypharmacy, and chronic kidney disease. This case underscores the critical importance of considering serotonin syndrome as a potential diagnosis in patients using serotonin and norepinephrine reuptake inhibitors, especially within vulnerable populations...
April 2024: Curēus
#59
JOURNAL ARTICLE
David Victorson, Kavita K Mishra, Joseph Sauer, Grace Langford, Carly Maletich, Bruriah Horowitz, Christina Sauer, Samir V Sejpal, John Kalapurakal
BACKGROUND: The most common and debilitating side effects of radiation therapy (RT) for prostate cancer (PC) are fatigue, sleep disturbance, anxiety, and depression. Previous research has reported palliative benefits from certain self-management approaches, such as mindfulness meditation. OBJECTIVE: To develop, pre-test, and evaluate the feasibility, acceptability and initial benefit of brief, audio-based mindfulness delivered during daily RT for PC compared to a relaxing music control...
2024: Glob Adv Integr Med Health
#60
JOURNAL ARTICLE
Yuanyuan Qian, Xiting Wang, Lulu Cai, Jiangxue Han, Zhu Huang, Yahui Lou, Bingyue Zhang, Yanjie Wang, Xiaoning Sun, Yan Zhang, Aisong Zhu
Recent trends suggest that Chinese herbal medicine formulas (CHM formulas) are promising treatments for complex diseases. To characterize the precise syndromes, precise diseases and precise targets of the precise targets between complex diseases and CHM formulas, we developed an artificial intelligence-based quantitative predictive algorithm (DeepTCM). DeepTCM has gone through multilevel model calibration and validation against a comprehensive set of herb and disease data so that it accurately captures the complex cellular signaling, molecular and theoretical levels of traditional Chinese medicine (TCM)...
April 2024: Journal of Pharmaceutical Analysis
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