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REVIEW
Xin-Ke Wei, Jun-Yi Huo, Qin Yang, Jing Li
Necrotizing fasciitis is a clinical, surgical emergency characterized by an insidious onset, rapid progression, and a high mortality rate. The disease's mortality rate has remained high for many years, mainly because of its atypical clinical presentation, which prevents many cases from being diagnosed early and accurately, resulting in patients who may die from uncontrollable septic shock and multi-organ failure. But unfortunately, no diagnostic indicator can provide a certain early diagnosis of NF, and clinical judgement of NF is still based on the results of various ancillary tests combined with the patient's medical history, clinical manifestations, and the physician's experience...
September 7, 2023: International Wound Journal
#42
REVIEW
Beatriz Merchán Gómez, Lucía Milla Collado, María Rodríguez
BACKGROUND AND OBJECTIVE: Artificial intelligence (AI) use is becoming increasingly prevalent directly or indirectly in daily clinical practice, including esophageal cancer (EC) diagnosis and treatment. Although the limits of its adoption and their clinical benefits are still unknown, any physician related to EC patients' management should be aware of the status and future perspectives of AI use in their field. The purpose of this review is to summarize the existing literature regarding the role of AI in diagnosis and treatment of EC...
August 30, 2023: Annals of Translational Medicine
#43
JOURNAL ARTICLE
Jon Salmanton-García, Francesco Marchesi, Philipp Koehler, Barbora Weinbergerová, Natasa Čolović, Iker Falces-Romero, Caterina Buquicchio, Francesca Farina, Jens VAN Praet, Monika M Biernat, Federico Itri, Lucia Prezioso, Carlo Tascini, Antonio Vena, Alessandra Romano, Mario Delia, Julio Dávila-Valls, Sonia Martín-Pérez, Esperanza Lavilla-Rubira, Tatjana Adžić-Vukičević, Daniel García-Bordallo, Alberto López-García, Mariana Criscuolo, Verena Petzer, Nicola S Fracchiolla, Ildefonso Espigado, Uluhan Sili, Stef Meers, Nurettin Erben, Chiara Cattaneo, Athanasios Tragiannidis, Eleni Gavriilaki, Martin Schönlein, Mirjana Mitrovic, Nikola Pantic, Maria Merelli, Jorge Labrador, José-Ángel Hernández-Rivas, Andreas Glenthøj, Guillemette Fouquet, Maria Ilaria Del Principe, Michelina Dargenio, María Calbacho, Caroline Besson, Milena Kohn, Stefanie Gräfe, Ditte Stampe Hersby, Elena Arellano, Gökçe MelisÇOLAK, Dominik Wolf, Monia Marchetti, Anna Nordlander, Ola Blennow, Raul Cordoba, Bojana Mišković, Miloš Mladenović, Martina Bavastro, Alessandro Limongelli, Laman Rahimli, Livio Pagano, Oliver A Cornely
INTRODUCTION: Molnupiravir and nirmatrelvir/ritonavir are antivirals used to prevent progression to severe SARS-CoV-2 infections, which reduce both hospitalization and mortality rates. Nirmatrelvir/ritonavir was authorised in Europe in December 2021, while molnupiravir is not yet licensed in Europe as of February 2022. Molnupiravir may be an alternative to nirmatrelvir/ritonavir, because it displays less frequent drug-drug interactions and contraindications. A caveat connected to molnupiravir derives from the mode of action inducing viral mutations...
August 13, 2023: International Journal of Antimicrobial Agents
#44
JOURNAL ARTICLE
Beatrice Maranini, Stefano Mandrioli, Giovanni Ciancio, Fabio Fabbian, Manlio Galiè, Marcello Govoni
OBJECTIVES: To evaluate the prevalence of temporomandibular disorders (TMD) in a monocentric cohort of patients affected by psoriatic arthritis (PsA), and to investigate the accuracy of temporomandibular joint (TMJ) ultrasound (US) compared with clinical evaluation and clinimetric composite index in assessing TMJ involvement. METHODS: We conducted a prospective cohort study of patients diagnosed with PsA who underwent at least one TMJ US examination and maxillofacial surgeon's evaluation between 2018 and 2021...
August 3, 2023: Clinical and Experimental Rheumatology
#45
JOURNAL ARTICLE
Ritwika Mallik, Judith Carpenter, Anjali Zalin
Obesity is a chronic, progressive and relapsing disease, characterised by the presence of abnormal or excess adiposity that impairs health and social wellbeing. It is associated with obesity-related disease complications, health inequalities and premature death. Clinical evaluation of obesity requires a thorough history and examination. Assessment should focus not only on anthropometric measurements, but also on the mental, metabolic, mechanical and monetary impact of adiposity, including multiple health conditions...
July 2023: Clinical Medicine: Journal of the Royal College of Physicians of London
#46
JOURNAL ARTICLE
Benoît Misset, Philippe Aegerter, Rym Boulkedid, Corinne Alberti, Christophe Baillard, Bertrand Guidet, Marc Beaussier
OBJECTIVES: No consensus criteria describe the medical eligibility of the patients to intermediate care units (IMCUs). In this first part of the UNISURC project, we aimed to develop criteria based on a consensus of physicians from the main specialties involved in IMCU admission decisions. DESIGN: We selected criteria from IMCU literature, scoring systems and intensive care unit nursing workload. We submitted these criteria to a panel of experts in a Delphi survey...
July 24, 2023: BMJ Open
#47
JOURNAL ARTICLE
Maija Paukkunen, Leena Ala-Mursula, Birgitta Öberg, Jaro Karppinen, Tuulikki Sjögren, Heidi Riska, Riku Nikander, Allan Abbott
BACKGROUND: The Determinants of Implementation Behavior Questionnaire (DIBQ) measures facilitators or barriers of healthcare professionals' implementation behaviors based on the current implementation research on practice and policy. The DIBQ covers 18 domains of the Theoretical Domains Framework and consists of 93 items. A previously tailored version (DIBQ-t) covering 10 domains and 28 items focuses on implementing best-practice low back pain care. AIM: To tailor a shortened version of DIBQ to multiprofessional rehabilitation context with cross-cultural adaptation to Finnish language...
July 24, 2023: European Journal of Physical and Rehabilitation Medicine
#48
JOURNAL ARTICLE
Louise Nadeau, Marc Valleur
BACKGROUND AND AIMS: In 1561, physician and philosopher Pascasius Justus Turq published a monograph on the description and treatment of pathological gambling. When the monograph came to the attention of the authors in 2006, there existed no known translation of it in any modern language. In 2014, it was translated and published in French. This paper analyses the monograph's key content elements and its place in the history of the concept of addiction. METHODS: A contextual analysis of the late Italian Renaissance, followed by key excerpts from the text and commentaries on the meaning and significance of the monograph...
July 22, 2023: Addiction
#49
REVIEW
Ajay Gupta, Richard F Riedel, Chirag Shah, Scott C Borinstein, Michael S Isakoff, Rashmi Chugh, Jeremy M Rosenblum, Erin S Murphy, Shauna R Campbell, Catherine M Albert, Stacey Zahler, Stefanie M Thomas, Matteo Trucco
Ewing sarcoma (ES) is a malignant tumor of bone and soft tissue that most often occurs in adolescents and young adults. Despite an international coordinated approach, several nuances, discrepancies, and debates remain in defining the standard of care for treating ES. In this review, the authors leverage the expertise assembled by formation of the National Ewing Sarcoma Tumor Board, a multi-institution, multidisciplinary virtual tumor board that meets monthly to discuss complicated and challenging cases of ES...
November 1, 2023: Cancer
#50
JOURNAL ARTICLE
Dimi Hoppe, Chaojie George Liu, Hanan Khalil
INTRODUCTION: Prescription drug monitoring programs (PDMP) are electronic databases used by prescribers and pharmacists to monitor the use of high-risk prescription medications subject to extramedical use. This study aimed to explore how Australian pharmacists and prescribers are using PDMPs in practice and to gain an understanding of barriers to tool use, as well as practitioner recommendations to increase tool usability and uptake. METHODS: Semi-structured interviews were conducted with pharmacists and prescribers who use a PDMP (n = 21)...
July 4, 2023: Drug and Alcohol Review
#51
JOURNAL ARTICLE
Erik Hohmann, Paul Bloomfield, Jiri Dvorak, Ruben Echemendia, Rachel M Frank, Janesh Ganda, Leigh Gordon, Louis Holtzhausen, Alan Kourie, Jerome Mampane, Michael Makdissi, Jon Patricios, Elizabeth Pieroth, Margot Putukian, Dina C Janse van Rensburg, Pierre Viviers, Vernon Williams, Jean de Wilde
PURPOSE: The purpose of this study was to perform a Delphi consensus for on-field and pitch-side assessment of sports related concussion (SRC). METHODS: Open-ended questions in rounds 1 and 2 were answered. The results of the first two rounds were used to develop a Likert style questionnaire for round 3. If agreement at round 3 was <80% for an item, if panel members were outside consensus or there were >30% neither agree/disagree responses, the results were carried forward into round 4...
June 28, 2023: Arthroscopy
#52
JOURNAL ARTICLE
Madeleine Haig, Caitlin Main, Danitza Chávez, Panos Kanavos
BACKGROUND: Digital health technologies (DHTs) can optimise healthcare costs and improve quality and efficiency of care. However, the fast-paced rate of innovation and varying evidence standards can make it difficult for decision-makers to assess these technologies in an efficient and evidence-based manner. OBJECTIVES: We sought to develop a comprehensive framework to assess the value of novel patient-facing DHTs used to manage chronic diseases by eliciting stakeholder value preferences...
June 27, 2023: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
#53
JOURNAL ARTICLE
Mary Showstark, Jami Smith, Trenton Honda
BACKGROUND: Physician Associate and Physician Associate comparable (PA/PA-comparable) professions are classified by the 2012 International Labour Classification of Occupations within ISCO group 2240 paramedical practitioners. However, to date, there is no single global framework which categorizes and/or describes their scopes of practice, or a single unifying occupational group name. In 2022, the World Health Organization (WHO) published its Global Competency and Outcomes Framework for Universal Health Coverage which focuses on the practice activities for health workers with a pre-service training pathway of 12-48 months, thus including many PA/PA-comparable roles...
June 23, 2023: Human Resources for Health
#54
JOURNAL ARTICLE
Alexander G Weil, Evan Dimentberg, Evan Lewis, George M Ibrahim, Olivia Kola, Chi-Hong Tseng, Jia-Shu Chen, Kao-Min Lin, Li-Xin Cai, Qing-Zhu Liu, Jiu-Luan Lin, Wen-Jing Zhou, Gary W Mathern, Matthew D Smyth, Brent R O'Neill, Roy Dudley, John Ragheb, Sanjiv Bhatia, Daniel Delev, Georgia Ramantani, Josef Zentner, Anthony C Wang, Christian Dorfer, Martha Feucht, Thomas Czech, Robert J Bollo, Galymzhan Issabekov, Hongwei Zhu, Mary Connolly, Paul Steinbok, Jian-Guo Zhang, Kai Zhang, Eveline Teresa Hidalgo, Howard L Weiner, Lily Wong-Kisiel, Samuel Lapalme-Remis, Manjari Tripathi, P Sarat Chandra, Walter Hader, Feng-Peng Wang, Yi Yao, Pierre Olivier Champagne, Tristan Brunette-Clément, Qiang Guo, Shao-Chun Li, Marcelo Budke, Maria Angeles Pérez-Jiménez, Christian Raftopoulos, Patrice Finet, Pauline Michel, Karl Schaller, Martin N Stienen, Valentina Baro, Christian Cantillano Malone, Juan Pociecha, Noelia Chamorro, Valeria L Muro, Marec von Lehe, Silvia Vieker, Chima Oluigbo, William D Gaillard, Mashael Al Khateeb, Faisal Al Otaibi, Niklaus Krayenbühl, Jeffrey Bolton, Phillip L Pearl, Aria Fallah
OBJECTIVES: Although hemispheric surgeries are among the most effective procedures for drug-resistant epilepsy (DRE) in the pediatric population, a large variability in outcomes remains. Identifying ideal hemispherectomy candidates is imperative to maximize the potential for seizure freedom. The objective was to develop an online, freely-accesible tool that accurately predicts the probability of seizure freedom for any patient at 1-, 2-, and 5-years post-hemispherectomy to provide clinicians accessible and reliable prognostic information to complement clinical judgement...
June 22, 2023: Epilepsia
#55
JOURNAL ARTICLE
Renato D Lopes, Pedro G M de Barros E Silva, Conrado Roberto Hoffmann Filho, Margaret Assad Cavalvante, Claudia Madeira Miranda, Rodrigo Barbosa Esper, Gustavo Glotz de Lima, Luiz Eduardo Fonteles Ritt, Rose Mary Ferreira Lisboa da Silva, Marcelo A Nakazone, Adail Paixão Almeida, Ricardo Pavanello, Carlos Eduardo Batista de Lima, Luciano Marcelo Backes, Lucas Hollanda Oliveira, Olga Ferreira de Souza, Adalberto Menezes Lorga Filho, Epotamenides Maria Good God, José Carlos Moura Jorge, Alcirley de Almeida Luiz, Simone Fialho Pereira Pimentel Martins, Rogério Carregoza Dantas, Ricardo D Oliveira Vieira, Leandro Ioschpe Zimerman, Álvaro Rabelo Alves Júnior, Márcio Jansen de Oliveira Figueiredo, Samara Pinheiro do Carmo Gomes, Lucas Martins de Lima, Lucas Petri Damiani, Ricardo Alkmim Teixeira, Alexandro Alves Fagundes, Eduardo Benchimol Saad
BACKGROUND: It is estimated that atrial fibrillation (AF) affects approximately 1.5 million people in Brazil; however, epidemiological data are limited. We sought to evaluate the characteristics, treatment patterns, and clinical outcomes in patients with AF in Brazil by creating the first nationwide prospective registry. METHODS: RECALL was a multicenter, prospective registry that included and followed for 1 year 4,585 patients with AF at 89 sites across Brazil from April 2012 to August 2019...
June 15, 2023: American Heart Journal
#56
JOURNAL ARTICLE
Veerle Piette, Luc Deliens, Sara Debulpaep, Joachim Cohen, Kim Beernaert
This study aims to evaluate the appropriateness of end-of-life care for children with genetic and congenital conditions. This is a decedent cohort study. We used 6 linked, Belgian, routinely collected, population-level databases containing children (1-17) who died with genetic and congenital conditions in Belgium between 2010 and 2017. We measured 22 quality indicators, face-validated using a previously published RAND/UCLA methodology. Appropriateness of care was defined as the overall "expected health benefit" of given healthcare interventions within a healthcare system exceeding expected negative outcomes...
June 16, 2023: European Journal of Pediatrics
#57
JOURNAL ARTICLE
Luigi Pannone, Sahar Mouram, Domenico Giovanni Della Rocca, Antonio Sorgente, Cinzia Monaco, Alvise Del Monte, Anaïs Gauthey, Antonio Bisignani, Rani Kronenberger, Gaetano Paparella, Robbert Ramak, Ingrid Overeinder, Gezim Bala, Alexandre Almorad, Erwin Ströker, Juan Sieira, Pedro Brugada, Gian Battista Chierchia, Mark La Meir, Carlo de Asmundis
AIMS: Hybrid atrial fibrillation (AF) ablation is a promising approach in non-paroxysmal AF. The aim of this study is to assess the long-term outcomes of hybrid ablation in a large cohort of patients after both an initial and as a redo procedure. METHODS AND RESULTS: All consecutive patients undergoing hybrid AF ablation at UZ Brussel from 2010 to 2020 were retrospectively evaluated. Hybrid AF ablation was performed in a one-step procedure: (i) thoracoscopic ablation followed by (ii) endocardial mapping and eventual ablation...
May 19, 2023: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
#58
JOURNAL ARTICLE
Shinji Inaba, Kazumichi Yamamoto, Tomohiro Kaga, Muhammad Wannous, Masatsugu Sakata, Osamu Yamaguchi, Toshi A Furukawa
INTRODUCTION: Although the ECG is an important diagnostic tool in medical practice, the competency of ECG interpretation is considered to be poor. Diagnostic inaccuracy involving the misinterpretation of ECG can lead to inappropriate medical judgements and cause negative clinical outcomes, unnecessary medical testing and even fatalities. Despite the importance of assessing ECG interpretation skills, there is currently no established universal, standardised assessment tool for ECG interpretation...
May 23, 2023: BMJ Open
#59
JOURNAL ARTICLE
Thomas R Arkell, Luke A Downey, Amie C Hayley, Sebastian Roth
IMPORTANCE: The use of cannabis as a medicine is becoming increasingly prevalent. Given the diverse range of conditions being treated with medical cannabis, as well as the vast array of products and dose forms available, clinical evidence incorporating patient-reported outcomes may help determine safety and efficacy. OBJECTIVE: To assess whether patients using medical cannabis report improvements in health-related quality of life over time. DESIGN, SETTING, AND PARTICIPANTS: This retrospective case series study was conducted at a network of specialist medical clinics (Emerald Clinics) located across Australia...
May 1, 2023: JAMA Network Open
#60
JOURNAL ARTICLE
André Bokelmann, Jan P Ehlers, Michaela Zupanic
OBJECTIVE: According to the legislator's ideas, the selection of medical students in Germany should no longer be based on the Abitur grade alone. This approach has already been implemented in the two-stage selection process at Witten/Herdecke University (UW/H) using several criteria. On the one hand, the present study aims to determine the prognostic value of the procedural components for the overall performance on the selection day. On the other hand, the different strategies of the applicants in processing the written task (phase 1) will be examined with regard to their application success...
April 28, 2023: Zeitschrift Für Evidenz, Fortbildung und Qualität Im Gesundheitswesen
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