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JOURNAL ARTICLE
Victor Mosquim, Giovanna Speranza Zabeu, Juliana Carvalho Jacomine, Daniella Cristo Santin, Heitor Marques Honório, Linda Wang
OBJECTIVES: To analyse the knowledge of dental undergraduates and dentists on the prevention, diagnosis and management of dentin hypersensitivity (DH); to compare their knowledge scores; and to understand the related variables using a regression model. METHODS: An original online questionnaire investigated the attitudes, self-reported knowledge ('how much they thought they knew') and real knowledge ('how much they really knew') of 132 students and 338 dentists. Data were analysed descriptively, both knowledge scores were compared using Mann-Whitney and Wilcoxon signed-rank tests and data were subjected to two multiple linear regression analyses considering real knowledge scores as the dependent variable (α < 0...
June 4, 2024: International Journal of Dental Hygiene
#42
JOURNAL ARTICLE
Pitambar Khanra, Johan Nakuci, Sarah Muldoon, Takamitsu Watanabe, Naoki Masuda
Energy landscape analysis is a data-driven method to analyse multidimensional time series, including functional magnetic resonance imaging (fMRI) data. It has been shown to be a useful characterization of fMRI data in health and disease. It fits an Ising model to the data and captures the dynamics of the data as movement of a noisy ball constrained on the energy landscape derived from the estimated Ising model. In the present study, we examine test-retest reliability of the energy landscape analysis. To this end, we construct a permutation test that assesses whether or not indices characterizing the energy landscape are more consistent across different sets of scanning sessions from the same participant (i...
June 4, 2024: European Journal of Neuroscience
#43
JOURNAL ARTICLE
Alexander S Homer, Viknesh S Kasthuri, Benjamin J Homer, Rishubh Jain, Emily K Gall, Kathryn Y Noonan
OBJECTIVES: The effect of Medicaid expansion as a part of the Affordable Care Act on vestibular schwannoma (VS) incidence overall and in marginalized populations has not yet been elucidated. The goal of this study was to determine if Medicaid expansion was associated with increases in VS incidence overall, as well as in patients of non-white race or in counties of low socioeconomic status (SES). METHODS: We performed a difference-in-difference (DiD) analysis from January 1st 2010-December 31st 2017 utilizing the Surveillance, Epidemiology, and End Results (SEER) database...
June 4, 2024: Laryngoscope
#44
JOURNAL ARTICLE
Lorenzo Tavelli, Shayan Barootchi
AIM: To assess ultrasonographic tissue elasticity at teeth and implant sites and its variation after peri-implant soft tissue augmentation with a connective tissue graft (CTG). METHODS: Twenty-eight patients, each contributing with one clinically healthy dental implant exhibiting a soft tissue dehiscence (PSTD), were included. Implant sites were augmented with CTG and monitored over 12 months. Ultrasonographic strain elastography, expressed as strain ratios (SR1 , SR2 , and SR3 , respectively) was assessed at baseline, 6-, and 12-month, and compared with the corresponding contralateral homologous natural tooth...
June 5, 2024: Journal of Periodontal Research
#45
RANDOMIZED CONTROLLED TRIAL
Anshu Yadav, Ranjeeta Kumari, Arun Goel, Girish Sindhwani, Narendra Singh, Rakhee Khanduri
CONTEXT: Asthma is a chronic disease and its chronicity demands therapy with minimal harm and a good impact on the quality of life of asthmatics. OBJECTIVE: This study evaluates the efficacy of structured yoga intervention integrated with routine care on asthma patients in improving their pulmonary function and quality of life. DESIGN: The study was a single-blind (outcome assessor) hospital-based randomized controlled trial. PARTICIPANTS: Adults between 18 to 60 years, diagnosed with mild to moderate asthma as per Global Initiative for Asthma guidelines, with no exacerbation in the past month before screening, were included in the study...
April 2024: Advances in Mind-body Medicine
#46
JOURNAL ARTICLE
Aurelie Hanin, Anthony D Jimenez, Margaret Gopaul, Hannah Asbell, Seyhmus Aydemir, Maysaa Merhi Basha, Ayush Batra, Charlotte Damien, Gregory S Day, Onome Eka, Krista Eschbach, Safoora Fatima, Madeline C Fields, Brandon Foreman, Elizabeth E Gerard, Teneille E Gofton, Hiba A Haider, Stephen T Hantus, Sara Hocker, Amy Jongeling, Mariel Kalkach Aparicio, Padmaja Kandula, Peter Kang, Karnig Kazazian, Marissa A Kellogg, Minjee Kim, Jong Woo Lee, Lara V Marcuse, Christopher M McGraw, Wazim Mohamed, Janet Orozco, Cederic M Pimentel, Vineet Punia, Alexandra M Ramirez, Claude Steriade, Aaron F Struck, Olga Taraschenko, Andrew K Treister, Mark S Wainwright, Ji Yeoun Yoo, Sahar Zafar, Daniel J Zhou, Deepti Zutshi, Nicolas Gaspard, Lawrence J Hirsch
In response to the evolving treatment landscape for new-onset refractory status epilepticus (NORSE) and the publication of consensus recommendations in 2022, we conducted a comparative analysis of NORSE management over time. Seventy-seven patients were enrolled by 32 centers, from July 2016 to August 2023, in the NORSE/FIRES biorepository at Yale. Immunotherapy was administered to 88% of patients after a median of 3 days, with 52% receiving second-line immunotherapy after a median of 12 days (anakinra 29%, rituximab 25%, and tocilizumab 19%)...
June 5, 2024: Epilepsia
#47
JOURNAL ARTICLE
Pier-Olivier Caron
A challenge in carrying out matching analyses is to deal with undefined log ratios. If any reinforcer or response rate equals zero, the logarithm of the ratio is undefined: data are unsuitable for analyses. There have been some tentative solutions, but they had not been thoroughly investigated. The purpose of this article is to assess the adequacy of five treatments: omit undefined ratios, use full information maximum likelihood, replace undefined ratios by the mean divided by 100, replace them by a constant 1/10, and add the constant ...
June 4, 2024: Journal of the Experimental Analysis of Behavior
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JOURNAL ARTICLE
Alison M Zeccola, Sarah E Allen
PURPOSE OF REVIEW: Adenomyosis is a common cause of abnormal uterine bleeding (AUB), dysmenorrhea, and pelvic pain. Definitive diagnosis and treatment have historically been by uterine histopathology at time of hysterectomy; however, advances in imaging have supported earlier diagnosis and subsequent conservative treatment. This review aims to update the evidence supporting the uterine-sparing, procedural management options with a focus on clinical outcomes. RECENT FINDINGS: Uterine artery embolization (UAE), radiofrequency ablation (RFA), high-intensity focused ultrasound (HIFU), percutaneous microwave ablation (PMWA), and adenomyomectomy are minimally invasive interventions proven to be effective in reducing AUB and dysmenorrhea due to adenomyosis...
May 24, 2024: Current Opinion in Obstetrics & Gynecology
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JOURNAL ARTICLE
Neeraj Kumar Chouhan, Abhisheik Eedara, Mamta N Talati, Sudha S S S S Ambadipudi, Sai Balaji Andugulapati, Srihari Pabbaraja
Breast cancer is the second most frequent cancer among women. Out of various subtypes, triple-negative breast cancers (TNBCs) account for 15% of breast cancers and exhibit more aggressive characteristics as well as a worse prognosis due to their proclivity for metastatic progression and limited therapeutic strategies. It has been demonstrated that AMP-activated protein kinase (AMPK) has context-specific protumorigenic implications in breast cancer cells. A set of glucosyltriazole amphiphiles, consisting of acetylated (9a-h) and unmodified sugar hydroxyl groups (10a-h), were synthesized and subjected to in vitro biological evaluation...
June 2024: Drug Development Research
#50
JOURNAL ARTICLE
Rahul Kumar, Mahuya De
Diesel degradation and bacterial growth were investigated in soil, marine water, and freshwater ecosystems using Acinetobacter baumannii IITG19, Providencia vermicola IITG20, and their mixed culture. Both bacteria were found to be effective in all three ecosystems, with the best degradation occurring in freshwater. Acinetobacter baumannii IITG19 showed higher degradation (59%, 62%, and 76%) than Providencia vermicola IITG20 (31%, 57%, and 67%) in soil, marine water, and freshwater, respectively. Alkanes showed higher degradation than naphthenes and aromatics for both strains...
June 5, 2024: Environmental Technology
#51
JOURNAL ARTICLE
Bing Cheng, Peng Du, Jin Xiao, Xiaowen Zhan, Lingyun Zhu
Utilizing aluminum-doped nano LLZO (Li6.28 La3 Zr2 Al0.24 O12 ) as the ceramic filler, we synthesized and optimized LLZO/PVDF/LiClO4 composite polymer electrolytes (CPEs) to achieve high ionic conductivity and good interfacial stability with metallic lithium. The research examines how the PVDF grade and the mass ratio of PVDF to LiClO4 affect the ionic conductivity, lithium metal compatibility, and overall performance of CPEs. The CPE using Kynar PVDF 741 and a PVDF-to-LiClO4 mass ratio of 2:1 emerged as superior, displaying a high ionic conductivity at room temperature (0...
June 5, 2024: ACS Applied Materials & Interfaces
#52
REVIEW
Yuwen Qi, Ying Li, Hua Wang, Anjin Wang, Xuelian Liu, Ziyan Liang, Yang Gao, Liqing Wei
Chimeric antigen receptor- (CAR-)modified T cells have been successfully used to treat blood cancer. With the improved research on anti-tumour adoptive cell therapy, researchers have focused on immune cells other than T lymphocytes. Natural killer (NK) cells have received widespread attention as barriers to natural immunity. Compared to T lymphocyte-related adoptive cell therapy, the use of NK cells to treat tumours does not cause graft-versus-host disease, significantly improving immunity. Moreover, NK cells have more sources than T cells, and the related modified cells are less expensive...
June 2024: Journal of Cellular and Molecular Medicine
#53
REVIEW
Pin-Chieh Lee, Mong-Wei Lin, Hsien-Chi Liao, Chan-Yi Lin, Pei-Hung Liao
INTRODUCTION: To utilize machine learning techniques to develop an association model linking lung cancer and environmental hormones to enhance the understanding of potential lung cancer risk factors and refine current nursing assessments for lung cancer. DESIGN: This study is exploratory in nature. In Stage 1, data were sourced from a biological database, and machine learning methods, including logistic regression and neural-like networks, were employed to construct an association model...
June 4, 2024: Journal of Nursing Scholarship
#54
JOURNAL ARTICLE
Shailaja Raghavan, Elham S Abu Alhaija, Yousef Nasrawi, Susan Al-Khateeb, Samer Sunna
INTRODUCTION: Mouthguards (MGs) have the potential to prevent contact sport-related dental injuries. However, varying perceptions of their effectiveness persist, influencing recommendations by dental professionals. AIM: To assess the attitudes, knowledge, and perceptions of orthodontists, other dental practitioners (general dentists and other dental specialists), and orthodontic patients involved in contact sports regarding the use of MGs. METHODOLOGY: A cross-sectional survey was designed to collect information from dental clinicians (orthodontists and other dental practitioners) and their orthodontic patients about using MGs during sports participation...
June 2024: Clinical and Experimental Dental Research
#55
JOURNAL ARTICLE
Tobias E Hector, Marta S Shocket, Carla M Sgrò, Matthew D Hall
Thermal acclimation can provide an essential buffer against heat stress for host populations, while acting simultaneously on various life-history traits that determine population growth. In turn, the ability of a pathogen to invade a host population is intimately linked to these changes via the supply of new susceptible hosts, as well as the impact of warming on its immediate infection dynamics. Acclimation therefore has consequences for hosts and pathogens that extend beyond simply coping with heat stress-governing both population growth trajectories and, as a result, an inherent propensity for a disease outbreak to occur...
June 2024: Global Change Biology
#56
JOURNAL ARTICLE
Peter J Taylor, Teresa C Kearney, Vincent Ralph Clark, Alexandra Howard, Monday V Mdluli, Wanda Markotter, Marike Geldenhuys, Leigh R Richards, Andrinajoro R Rakotoarivelo, Johan Watson, Julio Balona, Ara Monadjem
Hosting 1460 plant and 126 vertebrate endemic species, the Great Escarpment (hereafter, Escarpment) forms a semi-circular "amphitheater" of mountains girdling southern Africa from arid west to temperate east. Since arid and temperate biota are usually studied separately, earlier studies overlooked the biogeographical importance of the Escarpment as a whole. Bats disperse more widely than other mammalian taxa, with related species and intraspecific lineages occupying both arid and temperate highlands of the Escarpment, providing an excellent model to address this knowledge gap...
June 2024: Global Change Biology
#57
JOURNAL ARTICLE
Yen-Feng Wang, Fu-Chi Yang, Lu-An Chen, Ting-Yu Chang, Hui-Chen Su, Chun-Pai Yang, Yi-Hsien Tu, Yi-Shiang Tzeng, Shih-Pin Chen, Jong-Ling Fuh, Kuan-Lin Lai, Yu-Hsiang Ling, Wei-Ta Chen, Shuu-Jiun Wang
OBJECTIVE: To compare the real-world effectiveness and tolerability of calcitonin gene-related peptide (CGRP) monoclonal antibodies (mAbs) and onabotulinumtoxinA in chronic migraine (CM) patients. METHODS: This multicenter study involved retrospective analysis of prospectively collected data of CM patients treated with CGRP mAbs or onabotulinumtoxinA, including difficult-to-treat (DTT) patients (i.e., ≥3 preventive failures). Treatment outcomes were determined at 6 months based on prospective headache diaries and Migraine Disability Assessment (MIDAS)...
June 5, 2024: European Journal of Neurology
#58
JOURNAL ARTICLE
Wikan Ardiningrum, Martina Wiwie Setiawan Nasrun, Profitasari Kusumaningrum, Charles Evert Damping
BACKGROUND: Without appropriate support, taking care of people living with dementia may become a burden for family caregivers. Identifying the needs for caregivers can help them minimise the burden of caring and meet quality care for people living with dementia. METHODS: In the first phase, a content validity test was conducted on the Carers' Needs Assessment of Dementia (CNA-D) in the Indonesian version. The second phase, a sequential explanatory mixed-methods design, was conducted on 65 family caregivers in two stages...
June 4, 2024: Psychogeriatrics: the Official Journal of the Japanese Psychogeriatric Society
#59
JOURNAL ARTICLE
Jorge J Llibre-Guerra, Miao Jiang, Isaac Acosta, Ana Luisa Sosa, Daisy Acosta, Ivonne Z Jimenez-Velasquez, Mariella Guerra, Aquiles Salas, Ana M Rodriguez Salgado, Juan C Llibre-Guerra, Nedelys Díaz Sánchez, Matthew Prina, Alan Renton, Emiliano Albanese, Jennifer S Yokoyama, Juan J Llibre Rodriguez
INTRODUCTION: Leveraging the nonmonolithic structure of Latin America, which represents a large variability in social determinants of health (SDoH) and high levels of genetic admixture, we aim to evaluate the relative contributions of SDoH and genetic ancestry in predicting dementia prevalence in Latin American populations. METHODS: Community-dwelling participants aged 65 and older (N = 3808) from Cuba, Dominican Republic, Mexico, and Peru completed the 10/66 protocol assessments...
June 5, 2024: Alzheimer's & Dementia: the Journal of the Alzheimer's Association
#60
JOURNAL ARTICLE
Yoshiaki Mizutani, Satoshi Yanagisawa, Mizuki Ichikawa, Keisuke Nishio, Hiroya Sakai, Daishi Nonokawa, Yuichiro Makino, Hitomi Suzuki, Hitoshi Ichimiya, Yasuhiro Uchida, Junji Watanabe, Masaaki Kanashiro, Yasuya Inden, Toyoaki Murohara
INTRODUCTION: The underlying risks of asymptomatic embolization during high-power short-duration (HPSD) ablation for atrial fibrillation remain unclear. We aimed to evaluate microembolic signals (MESs) during HPSD ablation with power settings of 50 and 90 W in comparison with those during cryoballoon (CB) ablation using a novel carotid ultrasound-Doppler system that classifies solid and air bubble signals using real-time monitoring. METHODS AND RESULTS: Forty-seven patients underwent HPSD ablation using radiofrequency (RF), and 13 underwent CB ablation...
June 4, 2024: Journal of Cardiovascular Electrophysiology
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