keyword
https://read.qxmd.com/read/38732518/vitamin-d3-regulates-energy-homeostasis-under-short-term-fasting-condition-in-zebrafish-danio-rerio
#1
JOURNAL ARTICLE
Qingyang Du, Rui Shao, Wentao Wang, Hui Zhang, Xinmeng Liao, Zhihao Wang, Zhan Yin, Qinghui Ai, Kangsen Mai, Xiao Tang, Min Wan
Vitamin D3 (VD3) is a steroid hormone that plays pivotal roles in pathophysiology, and 1,25(OH)2D3 is the most active form of VD3. In the current study, the crucial role of VD3 in maintaining energy homeostasis under short-term fasting conditions was investigated. Our results confirmed that glucose-depriving pathways were inhibited while glucose-producing pathways were strengthened in zebrafish after fasting for 24 or 48 h. Moreover, VD3 anabolism in zebrafish was significantly suppressed in a time-dependent manner under short-fasting conditions...
April 25, 2024: Nutrients
https://read.qxmd.com/read/38729367/no-evidence-of-an-association-between-size-and-levels-of-four-per-and-polyfluorinated-substances-pfas-in-perch-perca-fluviatilis
#2
JOURNAL ARTICLE
H Waldetoft, O M Karlsson, R Awad
It was assessed how the size of perch (Perca fluviatilis) is related to levels of four per- and polyfluorinated substances (PFAS) in its muscle tissue. These were PFOS, PFNA, PFOA, and PFHxS, for which the sum, denoted as ΣPFAS4 , has a tolerable intake derived by the European Food Safety Authority. The results indicate that, in contrast to, e.g., mercury levels, ΣPFAS4 levels in perch muscle do not increase with increasing weight of the fish, which implies that consuming larger perch does not increase the risk of exceeding the TWI of ΣPFAS4 , in relation to consuming smaller perch...
May 8, 2024: Science of the Total Environment
https://read.qxmd.com/read/38726628/-vivifrail-protocol-as-a-method-of-muscle-strengthening-in-frail-older-adults
#3
JOURNAL ARTICLE
Juan Martín Mancera Alzate, Lina María Rodríguez Vélez
No abstract text is available yet for this article.
April 29, 2024: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://read.qxmd.com/read/38722856/comparing-preferences-to-evaluations-of-barrier-self-efficacy-for-two-strength-training-programs-in-us-older-adults
#4
COMPARATIVE STUDY
Jordan D Kurth, Christopher N Sciamanna, Cheyenne Herrell, Matthew Moeller, Jonathan G Stine
BACKGROUND/OBJECTIVES: Engagement in regular physical activity is one of the best strategies for older adults to remain healthy. Unfortunately, only 35% of older adults meet guidelines for muscle strengthening activities. Eliciting participant preferences is one possible way to improve physical activity engagement. However, other sources of participant input to improve uptake and maintenance remain uninvestigated. This study compared preferences to self-efficacy ratings for two strength training programs...
2024: PloS One
https://read.qxmd.com/read/38721465/a-brief-physiology-and-pathophysiology-of-the-bladder
#5
REVIEW
Jörgen Quaghebeur, Mark Bush, Dmitry Shkarupa, Jean-Jacques Wyndaele, Stefan De Wachter
The remit of this review is confined to experimental works and publications relevant to the integral theory of female urinary incontinence (IT). Since its first publication in 1990, the IT has challenged the general view that the pathogenesis of overactive bladder (OAB) (urge, frequency, nocturia) is unknown and there is no cure. According to the IT, normal function bladder control is binary, either closed or open. Control is cortical via a peripheral feedback component: oppositely acting reflex striated pelvic muscles contract against suspensory ligaments to close the urethra for continence, open it prior to evacuation, and stretch the vagina like a trampoline to prevent excess impulses from the urothelial stretch receptors which may cause unwanted urgency at low bladder volumes (OAB)...
April 22, 2024: Annals of Translational Medicine
https://read.qxmd.com/read/38721464/underactive-bladder-fowler-s-syndrome-are-potentially-curable-by-uterosacral-ligament-repair
#6
REVIEW
Maren Juliane Wenk, Mark Bush, Michael Swash, Bernard Liedl, Magdalena Witczak
Underactive bladder (UAB) is essentially an inability of the bladder to properly empty. UAB symptoms, when they co-occur with posterior fornix syndrome (PFS) symptoms (urge, frequency, nocturia, chronic pelvic pain), can be cured/improved, surgically by uterosacral ligament (USL) repair, non-surgically, by devices which give mechanical support of the USLs or strengthening pelvic muscle and ligaments with squatting-based exercises. The pathogenic pathway from weak USLs to UAB (and PFS) is that, when the muscles which externally open the posterior wall of the urethra contract against lax USLs, their contractile force weakens, and they cannot open the urethra adequately...
April 22, 2024: Annals of Translational Medicine
https://read.qxmd.com/read/38721462/structural-functional-and-dysfunctional-pelvic-anatomy
#7
REVIEW
Bernard Liedl, Giuseppe Dodi, Hiromi Inoue, Menahem Neuman, Elisabeth Del Amo
The structural basis of the Integral Theory is holistic. Four main pelvic muscles interact holistically with five main pelvic ligaments to maintain pelvic organ structure and function. The vagina is structurally weak. The support it provides to the bladder base is contingent on being stretched by opposite pelvic muscle forces, much like a trampoline. Its main role is to transmit muscle forces to facilitate continence, evacuation and control of urgency. Therefore, as an organ that cannot regenerate, the vagina should be conserved, and not excised...
April 22, 2024: Annals of Translational Medicine
https://read.qxmd.com/read/38721461/squatting-based-exercises-cure-bedwetting-in-children-and-improve-pain-and-bladder-symptoms-in-premenopausal-women
#8
REVIEW
Patricia M Skilling, Angel Garcia-Fernandez, Magdalena Witczak
This paper explores a practical approach to pelvic floor health called the Skilling technique. Unlike the commonly recommended "squeezing upwards" method which teaches a woman to voluntarily squeeze upwards (a learnt technique), the Skilling method is entirely reflex: the squatting-based exercises on which it is based, strengthen the three reflex pelvic muscle forces which pull against the suspensory ligaments pubourethral ligament (PUL) and uterosacral ligament (USL) to: close the urethra during effort (control of stress incontinence), open the urethra during micturition, and stretch the vagina in opposite directions to control inappropriate activation of the micturition reflex [overactive bladder (OAB)]...
April 22, 2024: Annals of Translational Medicine
https://read.qxmd.com/read/38719461/effect-of-blood-flow-restriction-with-low-intensity-resistance-training-in-patients-with-osteoarthritis-and-rheumatoid-arthritis-a-systematic-review-and-meta-analysis-based-on-randomized-controlled-trials
#9
JOURNAL ARTICLE
Junzhen Huang, Hun-Young Park
PURPOSE: This study evaluated the effects of blood flow restriction with low-intensity resistance training (BFR + LIRT) on pain, adverse events, muscle strength, and function in patients with osteoarthritis (OA) and rheumatoid arthritis (RA) through a systematic review and meta-analysis. METHODS: This study adhered to the guidelines of the Preferred Reporting Items for Systematic Review and Meta-Analyses 2020 (PRISMA 2020) and applied the A Measurement Tool to Assess Systematic Reviews 2 (AMSTAR2) standards to ensure the high quality of the systematic review...
March 2024: Physical activity and nutrition
https://read.qxmd.com/read/38714208/measurement-of-knee-extensor-torque-during-repetitive-peripheral-magnetic-stimulation-comparison-of-the-forces-induced-by-different-stimulators
#10
JOURNAL ARTICLE
Masanori Kamiue, Akio Tsubahara, Tomotaka Ito, Yasuhiro Koike
OBJECTIVE: To investigate the factors that induce strong contractions during repetitive peripheral magnetic stimulation (rPMS) and compare the muscle torque induced by two stimulators (Stim A and Stim B) with different coil properties. METHODS: rPMS was applied to the right vastus lateralis of 30 healthy young adults. Stim A contained a 10.1 cm2 rectangular iron core coil, while Stim B contained a 191 cm2 round coil. The knee extensor torque (KET) induced by rPMS at 30 Hz was measured isometrically and divided by the maximum voluntary contraction (MVC) to obtain a relative value of MVC (%MVC)...
May 8, 2024: Annals of Rehabilitation Medicine
https://read.qxmd.com/read/38713654/can-resistance-prehabilitation-training-bring-additional-benefits-in-valvular-cardiac-surgery-protocol-for-a-randomized-controlled-trial
#11
RANDOMIZED CONTROLLED TRIAL
Jorge Montero-Cámara, Francisco José Ferrer-Sargues, María José Segrera Rovira, Adrián Sarria Cabello, David Cuesta Peredo, Juan Antonio Margarit Calabuig, Noemí Valtueña-Gimeno, María Luz Sánchez-Sánchez
INTRODUCTION: Cardiovascular diseases (CVD) are a group of illnesses that include coronary heart disease, cerebrovascular disease, congenital heart disease and deep vein thrombosis. Major surgery is often chosen as the treatment of choice for CVD. The concept of fast-track rehabilitation after surgery appeared in the 1970s. Participation in these exercise-based prehabilitation programmes may decrease postoperative complications and length of hospital stay. The primary aim of the present study is to evaluate whether the implementation of an additional resistance training (RT) prehabilitation protocol within cardiac exercises based prehabilitation can reduce intensive care unit (ICU) length of stay, postoperative complications and hospital length of stay (LOS)...
2024: PloS One
https://read.qxmd.com/read/38709941/distal-abdominal-oblique-avulsion-injuries-in-two-collegiate-hockey-players-a-case-report
#12
JOURNAL ARTICLE
Ryan Narciso, Lawrence Venis, Nathan Cardoos
While injuries to the abdominal oblique muscles near their origin at the lower ribs are commonly seen in sports that require explosive trunk rotational movements such as baseball and tennis, there are few reports in the literature of avulsion injuries to these muscles from their distal attachments at the iliac crest. We present the case of two collegiate male hockey players who suffered such injuries as a result of a direct impact mechanism while rotated at the waist. These injuries should be suspected when patients have significant pain in the lower abdominal region worsened by flexion and rotation of the trunk and can be accurately characterized by musculoskeletal ultrasound or MRI...
May 1, 2024: Current Sports Medicine Reports
https://read.qxmd.com/read/38707851/muscle-activity-and-kinematics-during-three-hamstring-strengthening-exercises-compared-to-sprinting-a-cross-sectional-study
#13
JOURNAL ARTICLE
Adelso Jorge, Eric Lichtenstein, Oliver Faude, Ralf Roth
BACKGROUND: During sprinting, the biceps femoris long head predominantly gets injured, while hamstring strengthening exercises predominantly activate the semitendinosus more effectively. Understanding how joint dominance influences hamstring activity may offer clarity on appropriate exercise selection in strengthening programs. PURPOSE: This study compared three hip-dominant hamstring exercises: the rocker, perpetuum mobile fast and slow (PMfast and PMslow) and the Nordic Hamstring exercise (NHE) on their potential to simulate sprint-like activity and kinematics...
2024: International Journal of Sports Physical Therapy
https://read.qxmd.com/read/38707059/effectiveness-of-rehabilitation-for-osteoarthritis-of-the-knee-a-scoping-review-of-network-meta-analyses
#14
REVIEW
Takashi Kitagawa, Takumi Denda, Wataru Okuyama, Ryo Miyachi, Keisuke Nakamura
BACKGROUND:  Although an increasing number of network meta-analyses have been conducted on the effectiveness of conservative therapy for knee osteoarthritis, these may have been poorly planned and executed.We aimed to review the qualities of a comprehensive set of network meta-analyses on rehabilitation therapies for knee osteoarthritis and provide an overview of the effectiveness of each therapy. METHODS: The eligibility criteria were as follows: (i) conservative rehabilitation was the primary treatment in the intervention group, (ii) included patients were diagnosed with knee osteoarthritis, and (iii) patient groups were aged ≤75 years, and rehabilitation interventions comprised exercise, orthotic, or physical therapies or patient education...
April 2024: Curēus
https://read.qxmd.com/read/38707025/transformative-physiotherapy-approach-in-an-80-year-old-female-a-case-report-of-managing-obstructive-sleep-apnea-for-improved-quality-of-life
#15
Rishika Gabada, Vaishnavi Yadav, Dhanshri Nikhade
Obstructive sleep apnea (OSA) presents a significant challenge to patients' overall health and well-being, characterized by upper airway collapse during sleep leading to fragmented and non-restorative sleep patterns. This case report describes an 80-year-old female patient presenting with breathlessness, obesity (BMI: 43 kg/m2 ), sleep disturbances, fatigue, attention deficits, reduced chest compliance, and a history of type 2 diabetes mellitus. Clinical findings revealed ongoing sleep disruptions, worsening breathlessness, progressive weakness, and decreased oxygen saturation levels...
April 2024: Curēus
https://read.qxmd.com/read/38705448/chronic-toxicity-of-sediment-bound-triclosan-on-freshwater-walking-catfish-clarias-magur-organ-level-accumulation-and-selected-enzyme-biomarker-responses
#16
JOURNAL ARTICLE
Debiprasad Kantal, Saurav Kumar, Satya Prakash Shukla, Sutanu Karmakar, Ashish Kumar Jha, Angom Baleshwor Singh, Kundan Kumar
Triclosan (TCS) is a biocide widely used in personal care and medicinal products. TCS persists in sediments and has been detected worldwide, making sediments a vital route of TCS exposure to aquatic organisms. This experiment explored the bioaccumulation and toxicological effects of TCS-contaminated sediment. The study revealed that the half-life of TCS in the sediment-water system was 21.52 days. Exposure of Clarias magur juveniles to 0.4 and 0.8 mg kg-1 TCS-spiked sediment resulted in high Biota-Sediment Accumulation Factor (BSAF) with the highest bioaccumulation in the liver (29...
May 3, 2024: Environmental Pollution
https://read.qxmd.com/read/38697042/foot-problems-in-older-adults-presenting-to-a-falls-and-balance-clinic
#17
JOURNAL ARTICLE
Josephine White, Andrea B Maier, Laura Iacobaccio, Rebecca Iseli
INTRODUCTION: Foot problems, including musculoskeletal problems, peripheral neuropathy, peripheral arterial disease and dermatologic pathology are common in older adults and are associated with increased risk of falling. Multicomponent podiatry interventions have been shown to reduce the incidence of falls. This paper aims to identify older adults requiring podiatry input in a Falls and Balance clinic; to describe the model of foot health care they receive; to explore cross-sectional associations between foot problems and function and ultimately demonstrate the role of podiatry input in the multidisciplinary management of falls risk...
May 2, 2024: Gerontology
https://read.qxmd.com/read/38697023/effortful-swallow-maneuver-and-modifications-on-swallow-dynamics-in-healthy-adults
#18
JOURNAL ARTICLE
Ali Barikroo
INTRODUCTION: Effortful Swallow (ES) is a widely used technique in dysphagia management, believed to strengthen oropharyngeal muscles and enhance swallowing safety and efficiency. Although its impact on the oral phase of swallowing is well-documented, its effects on pharyngeal swallowing physiology remain inconsistent. This study aimed to elucidate the effects of ES on swallowing kinematics and timing, addressing existing inconsistencies in the literature. METHODS: This study involved 22 healthy adults using archived videofluoroscopic swallowing studies...
May 2, 2024: Folia Phoniatrica et Logopaedica
https://read.qxmd.com/read/38694207/effectiveness-of-a-sensorimotor-exercise-program-on-proprioception-balance-muscle-strength-functional-mobility-and-risk-of-falls-in-older-people
#19
JOURNAL ARTICLE
Ivelize Freire, Adérito Seixas
INTRODUCTION: Sensory systems provide the necessary information for a motor response to be provided. In this sense, the objective of this study is to evaluate the effectiveness of a sensorimotor exercise program on proprioceptive acuity, balance, muscle strength, functional mobility and risk of falls in institutionalized elderly. METHODOLOGY: 56 participants (84.6 ± 8.4 years) were randomly distributed between the control (CG, n = 28) and intervention groups (IG, n = 28)...
2024: Frontiers in Physiology
https://read.qxmd.com/read/38686590/differential-influence-of-quadriceps-rate-of-torque-development-on-single-and-double-leg-landing-mechanics-in-anterior-cruciate-ligament-reconstructed-and-control-females
#20
JOURNAL ARTICLE
Yu-Lun Huang, Colin M S Mulligan, Samuel T Johnson, Christine D Pollard, Kim Hannigan, Lyndsay Stutzenberger, Marc F Norcross
PURPOSE: The capacity to explosively contract quadriceps within the critical timeframe associated with anterior cruciate ligament (ACL) injury, quantified by the rate of torque development, is potentially essential for safe landing mechanics. This study aimed to investigate the influence of explosive quadriceps strength on ACL-related sagittal-plane landing mechanics in females with and without ACL reconstruction (ACLR). METHODS: Quadriceps explosive strength and landing mechanics were assessed in 19 ACLR and 19 control females during isometric contractions and double- and single-leg jump landings...
April 30, 2024: Knee Surgery, Sports Traumatology, Arthroscopy
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