Ulrike D B Krammer, Sylvia Tschida, Julia Berner, Stephanie Lilja, Olivier J Switzeny, Berit Hippe, Petra Rust, Alexander G Haslberger
Background: Regular, especially sustained exercise plays an important role in the prevention and treatment of multiple chronic diseases. Some of the underlying molecular and cellular mechanisms behind the adaptive response to physical activity are still unclear, but recent findings suggest a possible role of epigenetic mechanisms, especially miRNAs, in the progression and management of exercise-related changes. Due to the combination of the analysis of epigenetic biomarkers (miRNAs), the intake of food and supplements, and genetic dispositions, a "fitness score" was evaluated to assess the individual response to nutrition, exercise, and metabolic influence...
2022: Journal of the International Society of Sports Nutrition