Anjali Nayak, Rashu Raju, Paramita Das, Kuntal Das, A Suvitha, Biswa Ranjan Meher, Saad Alobid, Ali Ibrahim Almoteer, Moneer E Almadani, Ahmed Alshehri, Adel Alghamdi, Fuzail Ahmad, Syed Imam Rabbani, Syed Mohammed Basheeruddin Asdaq, Naira Nayeem
BACKGROUND: Alzheimer's disease (AD) is a severe, varied, and complex brain condition that gradually impairs memory and cognitive function. Epidemiological studies have shown that patients who have a history of long-term NSAID use have a decreased risk of developing AD. The objective of this study is to conduct the structural analysis of a novel ibuprofen prodrug and test its anti-Alzheimer's properties. METHODS: Computational and docking studies were conducted using AMBER 18 package...
January 2024: Saudi Pharmaceutical Journal: SPJ: the Official Publication of the Saudi Pharmaceutical Society