Amanda Larissa Dias Pacheco, Igor Santana de Melo, Fernanda Maria Araújo de Souza, Dannyele Cynthia Santos Pimentel Nicácio, Jucilene Freitas-Santos, Yngrid Mickaelli Oliveira Dos Santos, Maisa de Araújo Costa, Cibelle de Melo Bastos Cavalcante, José Gomes Dos Santos Neto, Daniel Leite Góes Gitaí, Robinson Sabino-Silva, Cláudio Miranda Torres, Alexandre Urban Borbely, Marcelo Duzzioni, Ashok K Shetty, Olagide Wagner de Castro
Crack users suffer the effects of cocaine present in the drug and the action of other active compounds from its pyrolysis. An emergent fact is an increase in the number of pregnant crack cocaine users. Studies suggest that crack cocaine and its metabolites cross the placenta, promoting premature birth, fever, irritability, sweating, and seizures in the early months of life. In children, the effects of crack cocaine have been associated with cognitive deficits, difficulty in verbalization, aggressiveness, and depression, besides enhancing the susceptibility to epileptic seizures, including status epilepticus (SE) in adulthood...
January 13, 2021: European Neuropsychopharmacology: the Journal of the European College of Neuropsychopharmacology