Use the keywords feature with a free QxMD account.
Use Read by QxMD to access full text via your institution or open access sources.
Read also provides personalized recommendations to keep you up to date in your field.
Existing User
Sign InNew to Read
Sign Up#1
JOURNAL ARTICLE
Ivana Cizmarova, Peter Mikus, Martin Svidrnoch, Juraj Piestansky
Monitoring plasma concentrations of β-lactam antibiotics is crucial, particularly in critically ill patients, where variations in concentrations can lead to treatment failure or adverse events. Standardized antimicrobial regimens may not be effective for all patients, especially in special groups with altered physiological parameters. Pharmacokinetic/pharmacodynamic (PK/PD) studies highlight the time-dependent antibacterial activity of these antibiotics, emphasizing the need for personalized dosing. Therapeutic drug monitoring (TDM) is essential, requiring rapid and accurate analytical methods for precise determination of drugs in biological material (typically plasma or serum)...
April 19, 2024: Pharmaceuticals
#2
JOURNAL ARTICLE
Vadivel Anbuganesan, Ramasamy Vishnupradeep, L Benedict Bruno, Krishnan Sharmila, Helena Freitas, Mani Rajkumar
Plants are often exposed to multiple stresses, including heavy metals (HM) and drought, which limit the plant growth and productivity. Though biochar or plant growth-promoting rhizobacteria (PGPR) have been widely used for alleviating HM or drought stress in plants, the study of the effects of combined treatment with biochar and PGPR under simultaneous HM and drought stress is limited. This study investigated individual and combined effects of groundnut shell biochar (GS-BC) and PGPR Bacillus pseudomycoides strain ARN7 on Zea mays growth, physiology, and HM accumulation, along with their impact on soil enzymes under HM (Ni and Zn), drought, or HM+drought stress...
April 19, 2024: Plants (Basel, Switzerland)
#3
JOURNAL ARTICLE
Reza Bahmani, Farhang Razavi, Seyed Najmmaddin Mortazavi, Gholamreza Gohari, Antonio Juárez-Maldonado
The application of natural polymer-based coatings presents a viable approach to prolong the longevity of fruits and tissue damage. This study investigates the impact of treatments involving glycine betaine (GB), chitosan (CTS), and chitosan-coated glycine betaine nanoparticles (CTS-GB NPs) on preserving the quality and reducing decay in strawberry fruits. The fruits were subjected to treatments with GB (1 mM), CTS (0.1%), CTS-GB NPs (0.1%), or distilled water at 20 °C for 5 min, followed by storage at 4 °C for 12 days...
April 18, 2024: Plants (Basel, Switzerland)
#4
JOURNAL ARTICLE
Mohammad A Shafiee, Amireza Goli, Pouyan Shaker, Vishal Sharma, Yasmin Shahideh, Khrystyna Maryniak, Behrooz Broumand
In this brief communication, we reemphasize the importance of critical thinking in clinical practice using the example of edema. The common practice of thinking and inquiry by practicing clinicians has beneficial implications for healthcare by improving outcomes and patient care while alleviating the burden of misconceptions in practice. We provide an in-depth and interactive investigation of physiological concepts as a foundation for understanding body fluid dynamics. Finally, we offer a new classification of symptoms of heart failure...
March 2024: Iranian Journal of Kidney Diseases
#5
JOURNAL ARTICLE
Cindy Galindo, Leonid Livshits, Lama Tarabeih, Gregory Barshtein, Sharon Einav, Yuri Feldman
The sensitivity of cytosol water's microwave dielectric (MD) response to D-glucose uptake in Red Blood Cells (RBCs) allows the detailed study of cellular mechanisms as a function of controlled exposures to glucose and other related analytes like electrolytes. However, the underlying mechanism behind the sensitivity to glucose exposure remains a topic of debate. In this research, we utilize MDS within the frequency range of 0.5-40 GHz to explore how ionic redistributions within the cell impact the microwave dielectric characteristics associated with D-glucose uptake in RBC suspensions...
April 22, 2024: European Biophysics Journal: EBJ
#6
Jennifer deRiso, Malini Mukherjee, Madhusudhana Janga, Alicia Simmons, Michael Kareta, Jianning Tao, Indra Chandrasekar, Kameswaran Surendran
The plasticity and diversity of cell types with specialized functions likely defines the capacity of multicellular organisms to adapt to physiologic stressors. The kidney collecting ducts contribute to water, electrolyte, and pH homeostasis and are composed of mature intermingled epithelial cell types that are susceptible to transdifferentiate. The conversion of kidney collecting duct principal cells to intercalated cells is actively inhibited by Notch signaling to ensure urine concentrating capability. Here we identify Hes1, a target of Notch signaling, allows for maintenance of functionally distinct epithelial cell types within the same microenvironment by regulating mechanistic target of rapamycin complex 1 (mTORC1) activity...
April 9, 2024: bioRxiv
#7
JOURNAL ARTICLE
Jalal Al-Tabbal, Mohammad Al-Harahsheh, Jehad Y Al-Zou'by
Drought is a threat to food security and agricultural sustainability in arid and semi-arid countries. Using wasted silica nanoparticles could minimize water scarcity. A controlled study investigated wheat plant physiological and morphological growth under tap-water irrigation (80-100, 60-80, and 40-60% field capacity). The benefits of S1: 0%, S2: 5%, and S3: 10% nanoparticle silica soil additions were studied. Our research reveals that water stress damages the physiological and functional growth of wheat plants...
April 21, 2024: International Journal of Phytoremediation
#8
JOURNAL ARTICLE
Hassan Iqbal, Chen Yaning
The exogenous use of the redox compound (H2 O2 ) plays a significant role in abiotic stress tolerance. The present study investigated various H2 O2 application methods (seed priming, foliar spray, and surface irrigation) with varying concentration levels (0 mM, 5 mM, 10 mM, 15 mM, 40 mM, 80 mM, and 160 mM) to evaluate the efficiency of supplying exogenous H2 O2 to quinoa under water-deficit conditions. Drought stress reduced quinoa growth and yield by perturbing morphological traits, leading to the overproduction of reactive oxygen species and increased electrolyte leakage...
2024: Frontiers in Plant Science
#9
JOURNAL ARTICLE
Joshua L Rein, Ken Mackie, Thomas R Kleyman, Lisa M Satlin
Cannabis and synthetic cannabinoid consumption is increasing worldwide. Cannabis contains numerous phytocannabinoids that act on the G-protein-coupled cannabinoid receptors type 1 (CB1R) and type 2 (CB2R) expressed throughout the body, including the kidney. Essentially every organ, including the kidney, produces endocannabinoids (ECs), endogenous ligands to these receptors. Cannabinoids acutely increase urine output in rodents and humans, thus potentially influencing total-body water and electrolyte homeostasis...
April 18, 2024: American Journal of Physiology. Renal Physiology
#10
JOURNAL ARTICLE
Fatemeh Mousavi Nanehkaran, Seyed Mehdi Razavi, Alireza Ghasemian, Abazar Ghorbani, Meisam Zargar
Salinity stress significantly constrains agricultural productivity and vegetation decline worldwide, particularly in Iran. Potassium, the second most prevalent nutrient in plants, is well known to be essential for cell metabolism. Here, the effects of potassium fertilizer in two biogenic nanoparticles (K-NPs) and conventional (potassium sulfate) forms (0.1 mg/ml) on Melissa officinalis L. under salinity (0, 50, 100, and 150 mM) were investigated. The results demonstrated that stress markers (electrolyte leakage, malondialdehyde, and hydrogen peroxide) increased as salinity levels increased...
April 16, 2024: Environmental Science and Pollution Research International
#11
JOURNAL ARTICLE
Imre Cseresnyés, Tünde Takács, Anna Füzy
The root dielectric response was measured on a minute scale to assess its efficiency for monitoring short-term cadmium (Cd) toxicity non-destructively. Electrical capacitance (CR ), dissipation factor (DR ) and electrical conductance (GR ) were detected during the 24 to 168 h after Cd treatment (0, 20, 50 mg Cd2+ kg-1 substrate) in potted maize, cucumber and pea. Stress was also evaluated by measuring leaf chlorophyll content, Fv /Fm and stomatal conductance (gs ) in situ, and shoot and root mass and total root length after harvest...
April 12, 2024: Environmental Science and Pollution Research International
#12
JOURNAL ARTICLE
Kazuyoshi Ukena, Reiko Okada
The endocrine and neuroendocrine systems exert powerful and broad control over the regulation of homeostasis in animals. Secreted hormones play significant roles in lifetime-related events such as germ cell development, sexual maturation, development, metamorphosis, aging, feeding, and energy metabolism. Additionally, hormones, particularly sex steroid hormones, are involved in reproduction, including sexual behavior and dimorphism. Changes in body color protect against external enemies, and circadian rhythms direct physiology and behaviors in synchrony with light and dark cycles...
February 2024: Zoological Science
#13
JOURNAL ARTICLE
Philip J G M Voets
Clinical hyponatremia guidelines, protocols and flowcharts are a convenient means for clinicians to quickly establish an etiological diagnosis for hyponatremia, and facilitate its often complex analysis. Unfortunately, they often erroneously attribute multifactorial hyponatremia to a single cause, which is potentially dangerous. In this manuscript, a novel criterion is proposed to quickly determine the physiological relevance of non-osmotic arginine vasopressin (AVP) release, and to add nuance to hyponatremia analysis...
April 2024: Physiological Reports
#14
JOURNAL ARTICLE
B Badzynska, I Baranowska, J Sadowski
Endothelins and renal dopamine contribute to control of renal function and arterial pressure in health and various forms of experimental hypertension, the action is mediated by tonic activity of specific receptors. We determined the action mediated by endothelin type B and by dopamine D3 receptors (ETB-R, D3-R) in anaesthetized spontaneously hypertensive (SHR) and in deoxycorticosterone acetate (DOCA)-salt hypertensive rats. In rats of both hypertension models infused during 60 min into the interstitium of in situ kidney were either ETB-R antagonist, BQ788 (0...
February 2024: Journal of Physiology and Pharmacology: An Official Journal of the Polish Physiological Society
#15
JOURNAL ARTICLE
Stanislaw Klek, Isabel Martinez Del Rio Requejo, Gil Hardy, Liza Mei P Francisco, Osman Abbasoglu, Juan Carlos Ayala Acosta, Luis Miguel Becerra Granados, Kurt Boeykens, Sharon Carey, Michael Chourdakis, Charlene Compher, Joeri De Cloet, Sergiej Dubrov, Catalina Fuentes, Ana Karina García Sámano, María Eloisa García Velasquez, Cezanne Goos, José Guillermo Gutierrez Reyes, Lee V Joon, Andrius Klimasauskas, Regina Komsa, Zeljko Krznaric, Dina Ljubas, Claudia P Maza Moscoso, Rosa Larreategui, Liliana Mirea, Remy Meier, Ibolya Nyulasi, Irtun Oivind, Marina Panisic-Sekeljic, Kalliopi Anna Poulia, Henrik Højgaard Rasmussen, Patricia Savino, Pierre Singer, Peter Tamasi, Mehmet Uyar, Nguyen Viet Quynh Thu, Dan Waitzberg, Arved Weimann, Theodoric Wong, Jianchun Yu, Paulina Wojcik, Stephane Schneider
OBJECTIVE: Parenteral nutrition represents a therapeutic option for patients with type 3 intestinal failure. If used exclusively, parenteral nutrition has to be complete to provide all essential nutrients. The aim was to assess the availability of parenteral nutrition in all parts of the world, to better comprehend the global situation, and to prepare an action plan to increase access to parenteral nutrition. METHODS: An international survey using an electronic questionnaire was conducted in August 2019 and repeated in May 2022...
February 26, 2024: Nutrition
#16
JOURNAL ARTICLE
Margi Patel, Shaikhul Islam, Bernard R Glick, Nisha Choudhary, Virendra Kumar Yadav, Snehal Bagatharia, Dipak Kumar Sahoo, Ashish Patel
The growth of crop plants, particularly spinach ( Spinacia oleracea L.), can be significantly impeded by salinity and drought. However, pre-treating spinach plants with traditional biofertilizers like Jeevamrit and Beejamrit (JB) substantially reverses the salinity and drought-induced inhibitory effects. Hence, this study aims to elucidate the underlying mechanisms that govern the efficacy of traditional fertilizers. The present work employed comprehensive biochemical, physiological, and molecular approaches to investigate the processes by which JB alleviates abiotic stress...
2024: Frontiers in Microbiology
#17
JOURNAL ARTICLE
Elisabeth Beckmüller, Jeannette Kluess, Liane Hüther, Susanne Kersten, Mareike Kölln, Christian Visscher, Sven Dänicke, Angelika Grümpel-Schlüter
Farmgate balances are used as a tool for monitoring nutrient surpluses at farm level. In Germany, preparation of farmgate balances is legally mandatory and also requires data on chemical body composition, especially concentration of nitrogen (N) and phosphorus (P), of farm animals. It is well known that increased N and P efficiency results in lowered N and P excretions with the manure and therefore mitigates negative consequences of high N and P release into the environment (e.g. eutrophication of surface waters), especially in areas with high livestock density...
March 21, 2024: Archives of Animal Nutrition
#18
JOURNAL ARTICLE
Michela Palumbo, Lucia Bonelli, Bernardo Pace, Francesco Fabiano Montesano, Francesco Serio, Maria Cefola
Reducing fertilizer input is a goal for helping greenhouse farming to achieve higher sustainability in the production process while preserving overall crop performance and quality. Wild rocket plants were cultivated in a plastic greenhouse divided into two independent sectors, one for soil-bound (SbS) cultivation and another equipped for soilless (ScS) cultivation systems. In both SbS and ScS, the crop was subjected to treatments consisting of a high- and a low-input fertilization program (HF and LF treatment, respectively)...
February 10, 2024: Plants (Basel, Switzerland)
#19
JOURNAL ARTICLE
Shiwen Lin, Jie Yang, Yanrong Liu, Wanjun Zhang
Over expression of MsSPL12 improved alfalfa salt tolerance by reducing Na+ accumulation and increasing antioxidant enzyme activity and regulating down-stream gene expression. Improvement of salt tolerance is one of the major goals in alfalfa breeding. Here, we demonstrated that MsSPL12, an alfalfa transcription factor gene highly expressed in the stem cells, plays a positive role in alfalfa salt tolerance. MsSPL12 is localized in the nucleus and shows transcriptional activity in the presence of its C-terminus...
March 18, 2024: Plant Cell Reports
#20
Jonathan G Hedley, Kush Coshic, Aleksei Aksimentiev, Alexei A Kornyshev
In solution, DNA is a highly charged macromolecule which bears a unit of negative charge on each phosphate of its sugar-phosphate backbone. Although partially compensated by counterions adsorbed at or condensed near it, DNA still produces a substantial electric field in its vicinity, which is screened by buffer electrolyte at longer distances from the DNA. Such field has been explored so far predominantly within the scope of a primitive model of the electrolytic solution, not considering more complicated structural effects of the water solvent...
March 7, 2024: ArXiv
Make the most of Read.
Download the mobile app.
Download the mobile app.
Fetching more papers... 
