Korsakoff's | Page 2

Samir Kashyap, Bhagat Cheema, Vaninder Chhabra
Background: Epidermoid cysts are benign, congenital lesions that originate from ectodermal cells, they are most commonly found in the cerebellopontine angle, but rarely in the ventricular system. There is limited literature regarding the different microsurgical techniques utilized to approach these lesions. Methods: A 63-year-old female with a recurrent third ventricular epidermoid cyst underwent gross total resection utilizing an endoscopic technique. We also reviewed the various endoscopic/microsurgical approaches and outcomes reported in literature...
2019: Surgical Neurology International
David Pang, Pete Duffield, Ed Day
Regular heavy consumption of alcohol is associated with a wide range of physical, psychological and social problems. All health-care clinicians should be able to screen for and detect problematic levels of alcohol consumption in their patients, and deliver an effective brief intervention. When patients with alcohol dependence are admitted to hospital there must be an assessment of whether medication is required to prevent withdrawal symptoms and potential delirium tremens and withdrawal seizures. Medically assisted alcohol withdrawal using a long-acting benzodiazepine such as chlordiazepoxide should be carefully monitored and titrated to effect, and the clinician should be aware of the risk of Wernicke-Korsakoff syndrome and other complications...
September 2, 2019: British Journal of Hospital Medicine
(no author information available yet)
No abstract text is available yet for this article.
2019: Neuropsychiatric Disease and Treatment
Jan W Wijnia, Erik Oudman, André I Wierdsma, Misha J Oey, Jeroen Bongers, Albert Postma
OBJECTIVES: Vitamin deficiencies may reflect less-than-optimal health in select populations. The aim of this study was to determine whether vitamin D supplementation (VDs) after malnutrition may be adversely related to cancer diagnoses in a selected group of patients with alcoholic Wernicke-Korsakoff syndrome (WKS). METHOD: This was a retrospective cohort study of all patients admitted to Slingedael Korsakoff Center, from 1996 to 2018. The patients were subdivided into three predefined groups depending on differences in VDs: "early" supplementation, which started during or before the previous hospital admission, before the transfer to our center; "late" supplementation, which started later in our center; and "no" VDs received...
May 29, 2019: Nutrition
Eunice Kasse, Erik Oudman, Marloes Olivier, Jan W Wijnia, Albert Postma
(Wernicke-)Korsakoff's syndrome (KS) is a neuropsychiatric syndrome, caused by vitamin B1 (thiamine) deficiency often resulting from chronic alcohol consumption. KS is characterized by severe cognitive problems, such as impaired explicit memory and executive functions. Visuospatial perception (VSP) refers to the identification of objects (object perception), and the localization of objects (space perception). Object perception can be described as the cooperation between visual representation and semantic information on the objects' functional properties...
July 14, 2019: Journal of Clinical and Experimental Neuropsychology
Antonio Carota, Julien Bogousslavsky
Hallucinations, delusions, and confabulations are common symptoms between neurology and psychiatry. The neurological diseases manifesting with such symptoms (dementia, epilepsy, Korsakoff's disease, brain tumors, Parkinson's disease, migraine, right hemisphere stroke and others) would be the key to understand their biological mechanisms, while the cognitive sciences, neuropharmacology and functional neuroimaging would be the tools of such researches. It is possible to understand the perceptive rules of the mind and the mechanisms of the human consciousness based on these symptoms...
2019: Frontiers of Neurology and Neuroscience
Karen G Langer
Memory and forgetfulness have been viewed since antiquity from perspectives of physical, emotional, and spiritual states of well-being, and conceptualized philosophically. Numerous discussions of memory loss, or case reports, existed, but a fundamental advance in conceptualization of memory loss as a pathological clinical phenomenon originated when Sauvages classified "amnesia" as a medical disorder, in 1763. Originally, amnesia was recognized as a weakening or dissolution of memory, according to a taxonomy that ascribed known causes to the disorder...
2019: Frontiers of Neurology and Neuroscience
Vineet V Mishra, Ruchika A Verneker
Wernicke-Korsakoff syndrome (WKS) is a rare neurological disorder due to severe thiamine deficiency. It is most prevalent among alcoholics. However in nonalcoholics the prevalence varies from 0.04% to 0.13%. We report a case of WKS due to hyperemesis gravidarum. Primigravida patient with 16 weeks pregnancy with continuous vomiting for 1 month developed Wernicke's encephalopathy which progressed to Korsakoff psychosis. Patient was conservatively managed till term with appropriate thiamine replacement and antipsychotics...
June 19, 2019: Journal of Obstetrics and Gynaecology Research
E Fouarge, P Maquet
Chronic alcohol consumption results in multiple peripheral and central nervous system dysfunctions. Some are due to the direct action of alcohol or its derivatives, others are induced by the vitamin deficiencies associated with alcoholism, others are eventually related to the failure of other vital organs, such as the liver. In this short review, we describe alcohol-induced neuropathy, Gayet-Wernicke syndrome, Korsakoff syndrome, alcoholic dementia, Marchiafava-Bignami syndrome, hepatic encephalopathy, alcoholic epilepsy and manifestations of alcohol withdrawal...
May 2019: Revue Médicale de Liège
Georgios Nikolakaros, Timo Kurki, Arttu Myllymäki, Tuula Ilonen
Background: Wernicke's encephalopathy (WE) and Korsakoff syndrome (KS) are underdiagnosed. The DSM-5 has raised the diagnostic threshold by including KS in the major neurocognitive disorders, which requires that the patient needs help in everyday activities. Methods: We report clinical, neuropsychological, and radiological findings from a patient who developed Wernicke-Korsakoff syndrome as a result of alcohol use and weight loss due to major depression. We assess the diagnosis in the context of the scientific literature on KS and according to the DSM-IV and the DSM-5...
2019: Neuropsychiatric Disease and Treatment
Shirshendu Sinha, Archish Kataria, Bhanu Prakash Kolla, Nuria Thusius, Larissa L Loukianova
Wernicke encephalopathy (WE) was first described by Carl Wernicke in 1881. WE is caused by thiamine deficiency. Alcoholism is the most common etiologic factor associated with WE in the United States, but it can occur in any patient with a nutritional deficiency state such as hyperemesis gravidarum, intestinal obstruction, and malignancy. WE is a clinical diagnosis. The common findings include mental status changes, ocular dysfunction, and a gait apraxia, present in only 10% of cases. Only a few cases of WE are diagnosed before death...
June 2019: Mayo Clinic Proceedings
Mohamad El Haj, Ahmed A Moustafa, Jean-Louis Nandrino
AIMS: Prior research has been mainly concerned with the ability of patients with Korsakoff syndrome (KS) to project themselves into the past. Little is known about the patients' ability to project themselves into the future. We therefore compared past and future thinking in patients with KS. METHODS: We invited patients with KS and control participants to retrieve past events and reconstruct future events. Participants were also invited to rate subjective characteristics (i...
May 2, 2019: Alcohol and Alcoholism
Anil M Tuladhar, Frank-Erik de Leeuw
No abstract text is available yet for this article.
May 1, 2019: Brain
Erik Oudman
No abstract text is available yet for this article.
April 11, 2019: International Psychogeriatrics
Beth Lloyd, Erik Oudman, Mareike Altgassen, Albert Postma
Prospective memory (PM) is the ability to remember to carry out an intention in the future. PM is particularly impaired in Korsakoff syndrome (KS). We investigated the benefit of a smartwatch and smartphone compared to no aid in supporting time accuracy and PM task performance in KS. Time accuracy was improved with a smartwatch compared to the other conditions. Furthermore, the smartwatch and phone conditions were more effective than no aid in assisting memory for task content. Together these results suggest that using an external memory aid is beneficial for successful PM in KS...
April 10, 2019: Neurocase
Jeremy Boardman, Adam Zermansky
No abstract text is available yet for this article.
March 31, 2019: BMJ Case Reports
Nathalie Pruckner, Josef Baumgartner, Barbara Hinterbuchinger, Alexander Glahn, Sandra Vyssoki, Benjamin Vyssoki
AIMS: Patients with alcohol use disorder (AUD) frequently suffer from cognitive deficits ranging from mild symptoms to most severe forms. Wernicke encephalopathy (WE), caused by thiamine deficiency, is a potentially fatal syndrome characterized by the clinical triad of ophthalmoplegia, ataxia, and confusion. WE frequently presents in patients with AUD and, if left untreated, can progress to Wernicke-Korsakoff syndrome, which constitutes severe anterograde amnesia, confabulation, and behavioral abnormalities...
2019: European Addiction Research
Erik Oudman, Jan W Wijnia, Misha Oey, Mirjam van Dam, Rebecca C Painter, Albert Postma
Pregnant women have an increased demand for thiamine. In hyperemesis gravidarum (HG) thiamine rapidly depletes, which can lead to Wernicke's Encephalopathy (WE). Our objective was to systematically review the signs and symptoms of WE in HG. We conducted our search from inception using Mesh terms hyperemesis, Wernicke Encephalopathy, Korsakoff's syndrome, and pregnancy. We searched Pubmed, Embase, Cochrane, Web of Science, Psychinfo, PiCarta, and Cinahl. We defined WE as mental, oculomotor, and motoric alterations and thiamine deficiency; HG was defined as severe nausea, and vomiting during pregnancy; adequate WE treatment as >500 mg/day intramuscular or intravenous...
May 2019: European Journal of Obstetrics, Gynecology, and Reproductive Biology
Shailendra Segobin, Alice Laniepce, Ludivine Ritz, Coralie Lannuzel, Céline Boudehent, Nicolas Cabé, Laurent Urso, François Vabret, Francis Eustache, Hélène Beaunieux, Anne-Lise Pitel
The thalamus, a relay organ consisting of several nuclei, is shared between the frontocerebellar circuit and the Papez circuit, both particularly affected in alcohol use disorder. Shrinkage of the thalamus is known to be more severe in alcoholics with Korsakoff's syndrome than in those without neurological complications (uncomplicated alcoholics). While thalamic atrophy could thus be a key factor explaining amnesia in Korsakoff's syndrome, the loci and nature of alterations within the thalamic nuclei in uncomplicated alcoholics and alcoholics with Korsakoff's syndrome remains unclear...
May 1, 2019: Brain
Ahmed A Shible, Deepa Ramadurai, Daniel Gergen, Paul M Reynolds
BACKGROUND Beriberi due to thiamine (vitamin B1) deficiency has two clinical presentations. Patients with dry beriberi present with neuropathy, and patients with wet beriberi present with heart failure, with or without neuropathy. Dry beriberi can mimic the most common form of Guillain-Barre syndrome (GBS), an acute inflammatory demyelinating polyradiculoneuropathy (AIDP). Severe thiamine deficiency results in Wernicke's encephalopathy. This report of a case of dry beriberi and Wernicke's encephalopathy due to thiamine deficiency includes a review of the literature...
March 13, 2019: American Journal of Case Reports
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