Julia E Herrmann, Morgan A Pence, Emanuel A Shapera, Ravi R Shah, Cédric G Geoffroy, Binhai Zheng
Ephrins and Eph receptor tyrosine kinases are cell-surface molecules that serve a multitude of functions in cell-cell communication in development, physiology, and disease. EphA4 is a promiscuous member of the EphA subclass of Eph receptors and can bind to both EphrinAs and EphrinBs. In addition to its well-established roles in guiding the development of neuronal connectivity, EphA4 has been implicated for a role in synaptic plasticity, vascular formation, axon regeneration, and central nervous system repair following injury...
February 2010: Genesis: the Journal of Genetics and Development