Rachele Danieli, Martina Stella, Julian Leube, Johannes Tran-Gia, Clementine Marin, Carlos F Uribe, Bruno Vanderlinden, Nick Reynaert, Patrick Flamen, Hugo Levillain
BACKGROUND: Dosimetry after radiopharmaceutical therapy with 177 Lu (177 Lu-RPT) relies on quantitative SPECT/CT imaging, for which suitable reconstruction protocols are required. In this study, we characterized for the first time the quantitative performance of a ring-shaped CZT-based camera using two different reconstruction algorithms: an ordered subset expectation maximization (OSEM) and a block sequential regularized expectation maximization (BSREM) combined with noise reduction regularization...
October 18, 2023: EJNMMI Physics