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EDITORIAL
Viviany R Taqueti, Valentin Fuster
No abstract text is available yet for this article.
May 7, 2024: Journal of the American College of Cardiology
#2
EDITORIAL
Valentin Fuster
No abstract text is available yet for this article.
March 22, 2024: Journal of the American College of Cardiology
#3
EDITORIAL
Larry M Baddour, Valentin Fuster
No abstract text is available yet for this article.
April 9, 2024: Journal of the American College of Cardiology
#4
EDITORIAL
Pedro R Moreno, Valentin Fuster
No abstract text is available yet for this article.
March 30, 2024: Journal of the American College of Cardiology
#5
JOURNAL ARTICLE
Inés García-Lunar, Inmaculada Jorge, Jorge Sáiz, Núria Solanes, Ana Paula Dantas, Juan José Rodríguez-Arias, María Ascaso, Carlos Galán-Arriola, Francisco Rafael Jiménez, Elena Sandoval, Jorge Nuche, Maria Moran-Garrido, Emilio Camafeita, Montserrat Rigol, Javier Sánchez-Gonzalez, Valentín Fuster, Jesús Vázquez, Coral Barbas, Borja Ibáñez, Daniel Pereda, Ana García-Álvarez
Right ventricular (RV) failure remains the strongest determinant of survival in pulmonary hypertension (PH). We aimed to identify relevant mechanisms, beyond pressure overload, associated with maladaptive RV hypertrophy in PH. To separate the effect of pressure overload from other potential mechanisms, we developed in pigs two experimental models of PH (M1, by pulmonary vein banding and M2, by aorto-pulmonary shunting) and compared them with a model of pure pressure overload (M3, pulmonary artery banding) and a sham-operated group...
March 27, 2024: Basic Research in Cardiology
#6
JOURNAL ARTICLE
Valentin Fuster
Each week, I record audio summaries for every paper in JACC, as well as an issue summary. This process has become a true labor of love due to the time they require, but I am motivated by the sheer number of listeners (16M+), and it has allowed me to familiarize myself with every paper that we publish. Thus, I have selected the top 100 papers (Original Investigations, Review Articles, Society Documents, and the Global Burden of Diseases) from distinct specialties each year. In addition to my personal choices, I have included papers that have been the most accessed or downloaded on our websites, as well as those selected by the JACC Editorial Board members...
March 12, 2024: Journal of the American College of Cardiology
#7
JOURNAL ARTICLE
Leticia Fernández-Friera, Ana García-Alvarez, Belen Oliva, Inés García-Lunar, Iris García, Andrea Moreno-Arciniegas, Sandra Gómez-Talavera, Cristina Pérez-Herreras, Javier Sánchez-González, Vicente Martínez de Vega, Xavier Rossello, Héctor Bueno, Antonio Fernández-Ortiz, Borja Ibañez, Javier Sanz, Valentín Fuster
AIMS: Evidence on the association between subclinical atherosclerosis (SA) and cardiovascular (CV) events in low-risk populations is scant. To study the association between SA burden and an ischemic scar (IS), identified by cardiac magnetic resonance (CMR), as a surrogate of CV endpoint, in a low-risk population. METHODS: A cohort of 712 asymptomatic middle-aged individuals from the Progression of Early SA (PESA-CNIC-Santander) study (median age 51 years, 84% male, median SCORE2 3...
March 1, 2024: European Heart Journal Cardiovascular Imaging
#8
EDITORIAL
Deepak L Bhatt, Martin E Goldman
No abstract text is available yet for this article.
March 5, 2024: Journal of the American College of Cardiology
#9
JOURNAL ARTICLE
Jesús Martínez-Gómez, Amaya de Cos-Gandoy, Juan Miguel Fernández-Alvira, Patricia Bodega, Mercedes de Miguel, Anna Tresserra-Rimbau, Emily P Laveriano-Santos, Sonia L Ramirez-Garza, Xavier Orrit, Isabel Carvajal, Ramón Estruch, Rosa María Lamuela-Raventós, Gloria Santos-Beneit, Valentín Fuster, Rodrigo Fernández-Jiménez
PURPOSE: To determine cardiovascular health (CVH) trajectories and their association with sociodemographic and cardiometabolic outcomes in adolescence. METHODS: One thousand eighty adolescents attending 24 secondary schools enrolled in the SI! Program for Secondary Schools trial in Spain were assessed at approximately 12, 14, and 16 years of age. CVH was assessed according to American Heart Association criteria based on seven metrics (smoking status, body mass index, physical activity, diet, blood pressure, total cholesterol, and blood glucose), and CVH trajectories were identified by latent class trajectory modeling...
February 6, 2024: Journal of Adolescent Health
#10
JOURNAL ARTICLE
Maria Giovanna Trivieri, Philip M Robson, Vittoria Vergani, Gina LaRocca, Angelica M Romero-Daza, Ronan Abgral, Ana Devesa, Levi-Dan Azoulay, Nicolas A Karakatsanis, Aditya Parikh, Christia Panagiota, Anna Palmisano, Louis DePalo, Helena L Chang, Joseph H Rothstein, Rima A Fayad, Marc A Miller, Valentin Fuster, Jagat Narula, Marc R Dweck, Adam Morgenthau, Adam Jacobi, Maria Padilla, Jason C Kovacic, Zahi A Fayad
BACKGROUND: Imaging with late gadolinium enhancement (LGE) magnetic resonance (MR) and 18 F-fluorodeoxyglucose (18 F-FDG) PET allows complementary assessment of myocardial injury and disease activity and has shown promise for improved characterization of active cardiac sarcoidosis (CS) based on the combined positive imaging outcome, MR(+)PET(+). OBJECTIVES: This study aims to evaluate qualitative and quantitative assessments of hybrid MR/PET imaging in CS and to evaluate its association with cardiac-related outcomes...
January 20, 2024: JACC. Cardiovascular Imaging
#11
JOURNAL ARTICLE
Gloria Santos-Beneit, Rodrigo Fernández-Jiménez, Valentín Fuster
No abstract text is available yet for this article.
January 24, 2024: JAMA Cardiology
#12
JOURNAL ARTICLE
Raquel Toribio-Fernández, Catarina Tristão-Pereira, Juan Carlos Silla-Castro, Sergio Callejas, Belen Oliva, Irene Fernandez-Nueda, Ines Garcia-Lunar, Cristina Perez-Herreras, José María Ordovás, Pilar Martin, Fiona Blanco-Kelly, Carmen Ayuso, Enrique Lara-Pezzi, Antonio Fernandez-Ortiz, Ana Garcia-Alvarez, Ana Dopazo, Fatima Sanchez-Cabo, Borja Ibanez, Marta Cortes-Canteli, Valentin Fuster
BACKGROUND: APOE is a known genetic contributor to cardiovascular disease, but the differential role APOE alleles play in subclinical atherosclerosis remains unclear. METHODS: The PESA (Progression of Early Subclinical Atherosclerosis) is an observational cohort study that recruited 4184 middle-aged asymptomatic individuals to be screened for cardiovascular risk and multiterritorial subclinical atherosclerosis. Participants were APOE -genotyped, and omics data were additionally evaluated...
January 23, 2024: Circulation Research
#13
REVIEW
Fadi N Salloum, Carlo G Tocchetti, Pietro Ameri, Hossein Ardehali, Aarti Asnani, Rudolf A de Boer, Paul Burridge, José-Ángel Cabrera, Javier de Castro, Raúl Córdoba, Ambra Costa, Susan Dent, Daniel Engelbertsen, María Fernández-Velasco, Mike Fradley, José J Fuster, Carlos Galán-Arriola, Inés García-Lunar, Alessandra Ghigo, Anna González-Neira, Emilio Hirsch, Borja Ibáñez, Richard N Kitsis, Suma Konety, Alexander R Lyon, Pilar Martin, Adolfo G Mauro, Manuel M Mazo Vega, Wouter C Meijers, Tomas G Neilan, Tienush Rassaf, Melanie Ricke-Hoch, Pilar Sepulveda, Paaladinesh Thavendiranathan, Peter van der Meer, Valentin Fuster, Bonnie Ky, Teresa López-Fernández
Despite improvements in cancer survival, cancer therapy-related cardiovascular toxicity has risen to become a prominent clinical challenge. This has led to the growth of the burgeoning field of cardio-oncology, which aims to advance the cardiovascular health of cancer patients and survivors, through actionable and translatable science. In these Global Cardio-Oncology Symposium 2023 scientific symposium proceedings, we present a focused review on the mechanisms that contribute to common cardiovascular toxicities discussed at this meeting, the ongoing international collaborative efforts to improve patient outcomes, and the bidirectional challenges of translating basic research to clinical care...
December 2023: JACC CardioOncology
#14
JOURNAL ARTICLE
Josep Iglesies-Grau, Ana Garcia-Alvarez, Belén Oliva, Guiomar Mendieta, Inés García-Lunar, José J Fuster, Ana Devesa, Cristina Pérez-Herreras, Antonio Fernández-Ortiz, Ramon Brugada, Borja Ibanez, Rodrigo Fernandez-Jimenez, Valentin Fuster
BACKGROUND: Elevated glycated hemoglobin (HbA1c) is associated with a higher burden of subclinical atherosclerosis (SA). However, the association with SA of earlier insulin resistance markers is poorly understood. The study assessed the association between the homeostatic model assessment of insulin resistance index (HOMA-IR) and SA in addition to the effect of cardiovascular risk factors (CVRFs) in individuals with normal HbA1c. METHODS: A cohort of 3,741 middle-aged individuals from the Progression of Early Subclinical Atherosclerosis (PESA) study with basal HbA1c < 6...
December 19, 2023: Cardiovascular Diabetology
#15
Makoto Araki, Seung-Jung Park, Harold L Dauerman, Shiro Uemura, Jung-Sun Kim, Carlo Di Mario, Thomas W Johnson, Giulio Guagliumi, Adnan Kastrati, Michael Joner, Niels Ramsing Holm, Fernando Alfonso, William Wijns, Tom Adriaenssens, Holger Nef, Gilles Rioufol, Nicolas Amabile, Geraud Souteyrand, Nicolas Meneveau, Edouard Gerbaud, Maksymilian P Opolski, Nieves Gonzalo, Guillermo J Tearney, Brett Bouma, Aaron D Aguirre, Gary S Mintz, Gregg W Stone, Christos V Bourantas, Lorenz Räber, Sebastiano Gili, Kyoichi Mizuno, Shigeki Kimura, Toshiro Shinke, Myeong-Ki Hong, Yangsoo Jang, Jin Man Cho, Bryan P Yan, Italo Porto, Giampaolo Niccoli, Rocco A Montone, Vikas Thondapu, Michail I Papafaklis, Lampros K Michalis, Harmony Reynolds, Jacqueline Saw, Peter Libby, Giora Weisz, Mario Iannaccone, Tommaso Gori, Konstantinos Toutouzas, Taishi Yonetsu, Yoshiyasu Minami, Masamichi Takano, O Christopher Raffel, Osamu Kurihara, Tsunenari Soeda, Tomoyo Sugiyama, Hyung Oh Kim, Tetsumin Lee, Takumi Higuma, Akihiro Nakajima, Erika Yamamoto, Krzysztof L Bryniarski, Luca Di Vito, Rocco Vergallo, Francesco Fracassi, Michele Russo, Lena M Seegers, Iris McNulty, Sangjoon Park, Marc Feldman, Javier Escaned, Francesco Prati, Eloisa Arbustini, Fausto J Pinto, Ron Waksman, Hector M Garcia-Garcia, Akiko Maehara, Ziad Ali, Aloke V Finn, Renu Virmani, Annapoorna S Kini, Joost Daemen, Teruyoshi Kume, Kiyoshi Hibi, Atsushi Tanaka, Takashi Akasaka, Takashi Kubo, Satoshi Yasuda, Kevin Croce, Juan F Granada, Amir Lerman, Abhiram Prasad, Evelyn Regar, Yoshihiko Saito, Mullasari Ajit Sankardas, Vijayakumar Subban, Neil J Weissman, Yundai Chen, Bo Yu, Stephen J Nicholls, Peter Barlis, Nick E J West, Armin Arbab-Zadeh, Jong Chul Ye, Jouke Dijkstra, Hang Lee, Jagat Narula, Filippo Crea, Sunao Nakamura, Tsunekazu Kakuta, James Fujimoto, Valentin Fuster, Ik-Kyung Jang
No abstract text is available yet for this article.
December 18, 2023: Nature Reviews. Cardiology
#16
JOURNAL ARTICLE
George A Mensah, Valentin Fuster, Christopher J L Murray, Gregory A Roth
No abstract text is available yet for this article.
December 19, 2023: Journal of the American College of Cardiology
#17
EDITORIAL
George A Mensah, Valentin Fuster, Gregory A Roth
No abstract text is available yet for this article.
December 19, 2023: Journal of the American College of Cardiology
#18
REVIEW
Ana Devesa, Borja Ibanez, Waqas A Malick, Elizabeth O Tinuoye, Jessica Bustamante, Carlos Peyra, Robert S Rosenson, Deepak L Bhatt, Gregg W Stone, Valentin Fuster
There is growing evidence that the atherosclerotic process that leads to symptomatic cardiovascular disease (CVD) starts at an early age. In young adults, exposure to low-density lipoprotein-cholesterol and other cardiovascular risk factor (CVRF) mediators, even at levels considered within normal limits, increases the prevalence of subclinical atherosclerosis and is associated with greater risk of cardiovascular events later in life. The optimal CVRF targets to prevent CVD in asymptomatic young individuals (<40 years) are unknown...
November 28, 2023: Journal of the American College of Cardiology
#19
JOURNAL ARTICLE
Guiomar Mendieta, Stuart Pocock, Virginia Mass, Andrea Moreno, Ruth Owen, Inés García-Lunar, Beatriz López-Melgar, Jose J Fuster, Vicente Andres, Cristina Pérez-Herreras, Hector Bueno, Antonio Fernández-Ortiz, Javier Sanchez-Gonzalez, Ana García-Alvarez, Borja Ibáñez, Valentin Fuster
BACKGROUND: Atherosclerosis is a systemic disease that frequently begins early in life. However, knowledge about the temporal disease dynamics (ie, progression or regression) of human subclinical atherosclerosis and their determinants is scarce. OBJECTIVES: This study sought to investigate early subclinical atherosclerosis disease dynamics within a cohort of middle-aged, asymptomatic individuals by using multiterritorial 3-dimensional vascular ultrasound (3DVUS) imaging...
November 28, 2023: Journal of the American College of Cardiology
#20
REVIEW
Fred M Kusumoto, John A Bittl, Mark A Creager, Harold L Dauerman, Anuradha Lala, Mary M McDermott, Justine Varieur Turco, Viviany R Taqueti, Valentin Fuster
The process of peer review has been the gold standard for evaluating medical science, but significant pressures from the recent COVID-19 pandemic, new methods of communication, larger amounts of research, and an evolving publication landscape have placed significant pressures on this system. A task force convened by the American College of Cardiology identified the 5 most significant controversies associated with the current peer-review process: the effect of preprints, reviewer blinding, reviewer selection, reviewer incentivization, and publication of peer reviewer comments...
November 21, 2023: Journal of the American College of Cardiology
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