Juliette Dupré, Mireille Le Dimna, Evelyne Hutet, Pascal Dujardin, Aurore Fablet, Aurélien Leroy, Isabelle Fleurot, Grégory Karadjian, Ferdinand Roesch, Ignacio Caballero, Olivier Bourry, Damien Vitour, Marie-Frédérique Le Potier, Grégory Caignard
African swine fever virus represents a significant reemerging threat to livestock populations, as its incidence and geographic distribution have surged over the past decade in Europe, Asia, and Caribbean, resulting in substantial socio-economic burdens and adverse effects on animal health and welfare. In a previous report, we described the protective properties of our newly thermo-attenuated strain (ASFV-989) in pigs against an experimental infection of its parental Georgia 2007/1 virulent strain. In this new study, our objective was to characterize the molecular mechanisms underlying the attenuation of ASFV-989...
2024: Frontiers in Immunology