Use the keywords feature with a free QxMD account.
Use Read by QxMD to access full text via your institution or open access sources.
Read also provides personalized recommendations to keep you up to date in your field.
Existing User
Sign InNew to Read
Sign Up#1
JOURNAL ARTICLE
Degenerative changes of the wrist in mixed martial arts and boxing based on the three column theory.
Erik Schiffner, Falk Hilsmann, Felix Lakomek, Christoph Beyersdorf, Joachim Windolf, David Latz
OBJECTIVE: Mixed Martial Arts (MMA) is a relatively young combat sport. In contrast to classic boxing, MMA combines techniques of grappling and striking. However, characteristic long-term effects of MMA on the wrist are discussed controversially. Aim of this study was to elucidate characteristic degenerative changes of the wrist from MMA fighters in comparison to classic boxers. METHODS: In this study, eleven professional MMA fighters and ten professional boxers with chronic wrist pain were examined and compared...
May 3, 2024: Physician and Sportsmedicine
#2
JOURNAL ARTICLE
Maxie Liebscher, Andrea Dell'Orco, Johanna Doll-Lee, Katharina Buerger, Peter Dechent, Michael Ewers, Klaus Fliessbach, Wenzel Glanz, Stefan Hetzer, Daniel Janowitz, Ingo Kilimann, Christoph Laske, Falk Lüsebrink, Matthias Munk, Robert Perneczky, Oliver Peters, Lukas Preis, Josef Priller, Boris Rauchmann, Ayda Rostamzadeh, Nina Roy-Kluth, Klaus Scheffler, Anja Schneider, Björn H Schott, Annika Spottke, Eike Spruth, Stefan Teipel, Jens Wiltfang, Frank Jessen, Emrah Düzel, Michael Wagner, Sandra Röske, Miranka Wirth
BACKGROUND: Participation in multimodal leisure activities, such as playing a musical instrument, may be protective against brain aging and dementia in older adults (OA). Potential neuroprotective correlates underlying musical activity remain unclear. OBJECTIVE: This cross-sectional study investigated the association between lifetime musical activity and resting-state functional connectivity (RSFC) in three higher-order brain networks: the Default Mode, Fronto-Parietal, and Salience networks...
2024: PloS One
#3
JOURNAL ARTICLE
Cari M Kitahara, Heljä-Marja Surcel, Roni Falk, Ruth M Pfeiffer, Tuija Männistö, Mika Gissler, Britton Trabert
Thyroid cancer more commonly affects women than men and is the third most frequently diagnosed cancer among women of reproductive age. We conducted a nested case-control study within the Finnish Maternity Cohort to evaluate pre-diagnostic sex steroid and thyroid function markers in relation to subsequent maternal papillary thyroid cancer. Cases (n = 605) were women ages 18-44 years, who provided an early-pregnancy (<20 weeks gestation) blood sample and were diagnosed with papillary thyroid cancer up to 11 years afterward...
May 2, 2024: International Journal of Cancer. Journal International du Cancer
#4
Pierre-Louis Lanvin, Dong Li, Solène Conrad, Armelle Magot, Xavier Micaelli, Yann Péréon, Marie Vincent, Bertrand Isidor, Damien Sternberg, Elizabeth M McCormick, Hakon Hakonarson, Sandra Mercier, Marni J Falk
OBJECTIVES: Heterozygous missense variants in MYBPC1 have been recently identified in 13 patients from 6 families with congenital myopathy with tremor. All the patients had mild skeletal myopathy invariably associated with a distinctive myogenic tremor and hypotonia with gradual clinical improvement. However, no phenotypic description has been reported for the neonatal respiratory impairment that patients may suffer. METHODS: We report 3 new patients from 2 independent families with congenital myopathy with tremor...
June 2024: Neurology. Clinical Practice
#5
JOURNAL ARTICLE
Mohammad Ejaz, Shahzad Ali, Muhammad Ali Syed, Falk Melzer, Rani Faryal, Maryam Dadar, Shahid Ahmed Abbasi, Hosny El-Adawy, Heinrich Neubauer
BACKGROUND: Human brucellosis is a neglected disease transmitted to humans from animals such as cattle, goats, dogs, and swine. The causative agents are bacteria of the genus Brucella , intracellular pathogens usually confined to the reproductive organs of their animal hosts causing sterility and abortions. The objective of the study was to determine the seroprevalence of brucellosis among women with spontaneous abortions (SAW) and compare this seroprevalence with that of healthy pregnant women (HPW)...
2024: Frontiers in Public Health
#6
JOURNAL ARTICLE
Steven Falk, Oliver Poole
We present a genome assembly from an individual male Myopa testacea (conopid fly; Arthropoda; Insecta; Diptera; Conopidae). The genome sequence is 243.3 megabases in span. Most of the assembly is scaffolded into 5 chromosomal pseudomolecules, including the X and Y sex chromosomes. The mitochondrial genome has also been assembled and is 17.61 kilobases in length. Gene annotation of this assembly on Ensembl identified 25,472 protein coding genes.
2024: Wellcome Open Research
#7
JOURNAL ARTICLE
Luca Marzano, Adam S Darwich, Raghothama Jayanth, Lethvall Sven, Nina Falk, Patrik Bodeby, Sebastiaan Meijer
Emergency department overcrowding is a complex problem that persists globally. Data of visits constitute an opportunity to understand its dynamics. However, the gap between the collected information and the real-life clinical processes, and the lack of a whole-system perspective, still constitute a relevant limitation. An analytical pipeline was developed to analyse one-year of production data following the patients that came from the ED (n = 49,938) at Uppsala University Hospital (Uppsala, Sweden) by involving clinical experts in all the steps of the analysis...
April 30, 2024: Scientific Reports
#8
Klaus W Neuhaus, Jan Kühnisch, Avijit Banerjee, Stefania Martignon, David Ricketts, Falk Schwendicke, Monique H van der Veen, Sophie Doméjean, Margherita Fontana, Adrian Lussi, Anahita Jablonski-Momeni, Fausto Medeiros Mendes, Gail Douglas, Gottfried Schmalz, Guglielmo Campus, Johan Aps, Keith Horner, Niek Opdam, Marie-Charlotte Huysmans, Christian H Splieth
INTRODUCTION: This consensus paper provides recommendations for oral health professionals on why and how to assess caries activity and progression with special respect to the site of a lesion. METHODS: An expert panel was nominated by the executive councils of the European Organization for Caries Research (ORCA) and the European Federation of Conservative Dentistry (EFCD). The steering committee built three working groups that were asked to provide recommendations on 1) caries detection and diagnostic methods, 2) caries activity and progression assessment and 3) obtain individualized caries diagnoses...
April 29, 2024: Caries Research
#9
RANDOMIZED CONTROLLED TRIAL
Cathleen Fedtke, Daniel Tilia, Klaus Ehrmann, Jennie Diec, Karen Lahav-Yacouel, Darrin Falk, Ravi C Bakaraju
SIGNIFICANCE: Spatio-Temporal Optical Phase technology utilizes film pairs containing optical elements applied to standard single-vision spectacle lenses. This technology provides a dynamic optical cue that may have efficacy in reducing the rate of myopia progression, but the visual performance of this technology is unknown. PURPOSE: This study aimed to assess the visual performance of film pairs containing optical elements (tests) and a film pair with no optical elements (control)...
April 1, 2024: Optometry and Vision Science: Official Publication of the American Academy of Optometry
#10
JOURNAL ARTICLE
Alexander M Fassmer, Sytse U Zuidema, Sarah I M Janus, Falk Hoffmann
PURPOSE: Assessing and comparing German and Dutch nursing home perspectives on residents' hospital transfers. METHODS: Cross-sectional study among German and Dutch nursing homes. Two surveys were conducted in May 2022, each among 600 randomly selected nursing homes in Germany and the Netherlands. The questionnaires were identical for both countries. The responses were compared between the German and Dutch participants. RESULTS: We received 199 German (response: 33...
April 29, 2024: European Geriatric Medicine
#11
EDITORIAL
Tsuyoshi Kaneko, Vinayak N Bapat, Ali M Alakhtar, Syed Zaid, Isaac George, Kendra J Grubb, Katherine Harrington, Luigi Pirelli, Marvin Atkins, Nimesh D Desai, Sabine Bleiziffer, Thilo Noack, Thomas Modine, Paolo Denti, Joerg Kempfert, Hendrik Ruge, Keti Vitanova, Volkmar Falk, Vinod H Thourani, Joseph E Bavaria, Michael J Reardon, Michael J Mack, Michael A Borger, Martin B Leon, Gilbert H L Tang, Shinichi Fukuhara
No abstract text is available yet for this article.
April 25, 2024: Journal of Thoracic and Cardiovascular Surgery
#12
REVIEW
Kathrin Wandscher, Falk Hoffmann, Christoph Heesen, Götz Thomalla, Anne Christin Rahn, Jasmin Helbach
BACKGROUND AND PURPOSE: This systematic review examines the effectiveness of motivational interviewing (MI) on medication adherence for preventing recurrent stroke and transient ischemic attack (TIA). METHODS: MEDLINE (via PubMed), CINAHL, PsycINFO, CENTRAL, and ClinicalTrials.gov were searched from inception to 12 June 2023. Randomized controlled trials comparing MI with usual care or interventions without MI in participants with any stroke type were identified and summarized descriptively...
April 27, 2024: European Journal of Neurology
#13
JOURNAL ARTICLE
Lisa Hübinger, Kerstin Wetzig, Roswitha Runge, Holger Hartmann, Falk Tillner, Katja Tietze, Marc Pretze, David Kästner, Robert Freudenberg, Claudia Brogsitter, Jörg Kotzerke
This work investigates the proposed enhanced efficacy of photodynamic therapy (PDT) by activating photosensitizers (PSs) with Cherenkov light (CL). The approaches of Yoon et al. to test the effect of CL with external radiation were taken up and refined. The results were used to transfer the applied scheme from external radiation therapy to radionuclide therapy in nuclear medicine. Here, the CL for the activation of the PSs (psoralen and trioxsalen) is generated by the ionizing radiation from rhenium-188 (a high-energy beta-emitter, Re-188)...
April 13, 2024: Pharmaceutics
#14
JOURNAL ARTICLE
Elisa Maria Brandenburg, Ralf Thomas Voegele, Michael Fischer, Falk Hubertus Behrens
Viticulture worldwide is challenged by grapevine trunk diseases (GTDs). Involvement of arthropods in the dissemination process of GTD pathogens, notably esca pathogens, is indicated after detection of associated pathogens on arthropod exoskeletons, and demonstration of transmission under artificial conditions. The present study is the first to quantify spore loads via qPCR of the esca-relevant pathogen Phaeomoniella chlamydospora on arthropods collected in German vineyards, i.e., European earwigs ( Forficula auricularia ), ants ( Formicidae ), and two species of jumping spiders ( Marpissa muscosa and Synageles venator )...
March 22, 2024: Journal of Fungi (Basel, Switzerland)
#15
JOURNAL ARTICLE
Carina Figueiredo, Carolin Psotta, Kavita Jayakumar, Anna Lielpetere, Tanushree Mandal, Wolfgang Schuhmann, Dónal Leech, Magnus Falk, Marcos Pita, Sergey Shleev, Antonio L De Lacey
Galactose monitoring in individuals allows the prevention of harsh health conditions related to hereditary metabolic diseases like galactosemia. Current methods of galactose detection need development to obtain cheaper, more reliable, and more specific sensors. Enzyme-containing amperometric sensors based on galactose oxidase activity are a promising approach, which can be enhanced by means of their inclusion in a redox polymer coating. This strategy simultaneously allows the immobilization of the biocatalyst to the electroactive surface and hosts the electron shuttling units...
March 30, 2024: Biosensors
#16
JOURNAL ARTICLE
Alexandra Strauss Starling, Yue Ren, Hongzhe Li, Jonathan M Spergel, Amanda B Muir, Kristle L Lynch, Chris A Liacouras, Gary W Falk
OBJECTIVES: There is limited longitudinal data on the impact of chronic therapy on the natural history of eosinophilic esophagitis [EoE], a chronic allergic disease of the esophagus. The purpose of this study was to evaluate if patients with well-controlled EoE were less likely to develop fibrostenotic complications. METHODS: Subjects were identified from a database of pediatric EoE patients at the Children's Hospital of Philadelphia started in 2000. Patients were then searched in adult medical records to identify patients who transitioned care...
April 25, 2024: American Journal of Gastroenterology
#17
JOURNAL ARTICLE
Alexander Iribarne, Sundos H Alabbadi, Alan J Moskowitz, Gorav Ailawadi, Vinay Badhwar, Marc Gillinov, Vinod H Thourani, Keith B Allen, Michael E Halkos, Nirav C Patel, Robert S Kramer, David D'Alessandro, Samantha Raymond, Helena L Chang, Lopa Gupta, Kathleen N Fenton, Wendy C Taddei-Peters, Michael W A Chu, Volkmar Falk, Joanna Chikwe, Neal Jeffries, Emilia Bagiella, Patrick T O'Gara, Annetine C Gelijns, Natalia N Egorova
BACKGROUND: Tricuspid valve annuloplasty (TA) during mitral valve repair (MVr) is associated with increased risk of permanent pacemaker (PPM) implantation, but the magnitude of risk and long-term clinical consequences have not been firmly established. OBJECTIVES: This study assesses the incidence rates of PPM implantation after isolated MVr and following MVr with TA as well as the associated long-term clinical consequences of PPM implantation. METHODS: State-mandated hospital discharge databases of New York and California were queried for patients undergoing MVr (isolated or with concomitant TA) between 2004 and 2019...
April 30, 2024: Journal of the American College of Cardiology
#18
JOURNAL ARTICLE
Josephin Wagner, Lauren M Park, Partha Mukhopadhyay, Csaba Matyas, Eszter Trojnar, Ruslan Damadzic, Jeesun Jung, Andrew S Bell, Lucas A Mavromatis, Ali M Hamandi, Daniel B Rosoff, Leandro F Vendruscolo, George F Koob, Pal Pacher, Falk W Lohoff
Alcohol Use Disorder (AUD) is a persistent condition linked to neuroinflammation, neuronal oxidative stress, and neurodegenerative processes. While the inhibition of proprotein convertase subtilisin/kexin type 9 (PCSK9) has demonstrated effectiveness in reducing liver inflammation associated with alcohol, its impact on the brain remains largely unexplored. This study aimed to assess the effects of alirocumab, a monoclonal antibody targeting PCSK9 to lower systemic low-density lipoprotein cholesterol (LDL-C), on central nervous system (CNS) pathology in a rat model of chronic alcohol exposure...
April 22, 2024: Brain, Behavior, and Immunity
#19
JOURNAL ARTICLE
Saumey Jain, Dimitrios Voulgaris, Surangrat Thongkorn, Rick Hesen, Alice Hägg, Mohsen Moslem, Anna Falk, Anna Herland
The clinical translation of induced pluripotent stem cells (iPSCs) holds great potential for personalized therapeutics. However, one of the main obstacles is that the current workflow to generate iPSCs is expensive, time-consuming, and requires standardization. A simplified and cost-effective microfluidic approach is presented for reprogramming fibroblasts into iPSCs and their subsequent differentiation into neural stem cells (NSCs). This method exploits microphysiological technology, providing a 100-fold reduction in reagents for reprogramming and a ninefold reduction in number of input cells...
April 24, 2024: Advanced Science (Weinheim, Baden-Wurttemberg, Germany)
#20
JOURNAL ARTICLE
Hannah Baumeister, Jacob W Vogel, Philip S Insel, Luca Kleineidam, Steffen Wolfsgruber, Melina Stark, Helena M Gellersen, Renat Yakupov, Matthias C Schmid, Falk Lüsebrink, Frederic Brosseron, Gabriel Ziegler, Silka D Freiesleben, Lukas Preis, Luisa-Sophie Schneider, Eike J Spruth, Slawek Altenstein, Andrea Lohse, Klaus Fliessbach, Ina R Vogt, Claudia Bartels, Björn H Schott, Ayda Rostamzadeh, Wenzel Glanz, Enise I Incesoy, Michaela Butryn, Daniel Janowitz, Boris-Stephan Rauchmann, Ingo Kilimann, Doreen Goerss, Matthias H Munk, Stefan Hetzer, Peter Dechent, Michael Ewers, Klaus Scheffler, Anika Wuestefeld, Olof Strandberg, Danielle van Westen, Niklas Mattsson-Carlgren, Shorena Janelidze, Erik Stomrud, Sebastian Palmqvist, Annika Spottke, Christoph Laske, Stefan Teipel, Robert Perneczky, Katharina Buerger, Anja Schneider, Josef Priller, Oliver Peters, Alfredo Ramirez, Jens Wiltfang, Michael T Heneka, Michael Wagner, Emrah Düzel, Frank Jessen, Oskar Hansson, David Berron
Memory clinic patients are a heterogeneous population representing various aetiologies of pathological aging. It is unknown if divergent spatiotemporal progression patterns of brain atrophy, as previously described in Alzheimer's disease (AD) patients, are prevalent and clinically meaningful in this group of older adults. To uncover distinct atrophy subtypes, we applied the Subtype and Stage Inference (SuStaIn) algorithm to baseline structural MRI data from 813 participants enrolled in the DELCODE cohort (mean ± SD age = 70...
April 24, 2024: Brain
Make the most of Read.
Download the mobile app.
Download the mobile app.
Fetching more papers... 
