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JOURNAL ARTICLE
Ben Amir, Sapir Barak Lanciano, Ronen Rubinshtein, Udi Nussinovitch
To determine whether young women who have experienced typical vasovagal syncope (tVVS) have altered autonomic response parameters, based on a battery of autonomic tests and maneuvers. Notably, previous studies including small cohorts and a partial list of tests yielded conflicting results. A total of 91 otherwise healthy women were included and divided according to those who had experienced tVVS (39 patients) or not (52 patients). Heart rate variability was evaluated at rest, under strict conditions, during 5 min of standing and during a deep breathing test...
May 3, 2024: Internal and Emergency Medicine
#2
JOURNAL ARTICLE
Bengt Herweg, Ritesh S Patel, Sami Noujaim, Joseph Spano, Nicholas Mencer, Pugazhendhi Vijayaraman
BACKGROUND: Cardioneuroablation (CNA) targeting ganglionated plexi has shown promise in treating vasovagal syncope. Only radiofrequency ablation has been used to achieve this goal thus far. OBJECTIVE: The purpose of this study was to investigate the utility of cryoballoon ablation (CBA) of the pulmonary veins (PVs) as a potential simplified approach to CNA. METHODS: We report our observations of autonomic modulation in a series of 17 patients undergoing CBA for atrial fibrillation and our early experience using CBA of the PVs in 3 patients with malignant vagal syncope...
April 2024: Heart rhythm O2
#3
Sabastain F Forsah, Derek Ugwendum, Divine Besong Arrey Agbor, Nancelle Ndema, Nkafu Bechem Ndemazie, Gauvain Kankeu Tonpouwo, Akua Aboah A Taylor, Nkeng Fuoching, Davene James-Gregory, Shannia Amoah, Vaithilingam Arulthasan, Jay Nfonoyim
Syncope is the transient loss of consciousness due to cerebral hypoperfusion. A significant number of individuals experience a syncopal attack at one stage of their lives. The common causes of syncope include vasovagal syncope, orthostatic hypotension, and cardiac causes. Drugs are also associated with causing syncope. The drugs involved are mostly those that depress the central nervous system, and concomitant use of more than one of such drugs increases the risk of syncope even further. Tizanidine and alcohol individually can cause hypotension and combining both drugs is not advised due to heightened central nervous system depression and profound hypotension...
March 2024: Curēus
#4
JOURNAL ARTICLE
Udi Nussinovitch, Sapir Barak-Lanciano, Itay Shavit, Ishay Avivi, Ella Haber-Kaptsenel, Hagar Palacci, Chen Chaiat, Ronen Rubinshtein
It is controversial whether people with vasovagal syncope (VVS) have abnormal autonomic responses at baseline and whether specific diagnostic manoeuvres have a diagnostic value. We investigated whether the pupillary light reflex and cardiac autonomic tests can be used to identify autonomic dysfunction in volunteers with a medical history of VVS. The study groups included 128 healthy volunteers, of whom 31 reported a history of typical VVS. The right pupil was evaluated using an automated, commercial infra-red pupillometer under strict conditions...
April 28, 2024: Clinical Physiology and Functional Imaging
#5
JOURNAL ARTICLE
J Gert van Dijk, Robert Sheldon, Richard Sutton
No abstract text is available yet for this article.
April 15, 2024: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
#6
JOURNAL ARTICLE
Xiao-Juan Du, Ya-Qian Huang, Xue-Ying Li, Ying Liao, Hong-Fang Jin, Jun-Bao Du
BACKGROUND: Vasovagal syncope (VVS) is the most common type of orthostatic intolerance in children. We investigated whether platelet-related factors related to treatment efficacy in children suffering from VVS treated with metoprolol. METHODS: Metoprolol-treated VVS patients were recruited. The median duration of therapy was three months. Patients were followed and divided into two groups, treament-effective group and treatment-ineffective group. Logistic and least absolute shrinkage selection operator regressions were used to examine treatment outcome variables...
April 13, 2024: World Journal of Pediatrics: WJP
#7
JOURNAL ARTICLE
Silvie Kotherová, Jakub Cigán, Lenka Štěpánková, Mária Vyskočilová, Simona Littnerová, Anastasia Ejova, Milan Sepši
Buddhist meditation practices, including Samadhi meditation, which forms the basis for mindfulness practice, are broadly promoted as pathways to wellbeing, but evidence of their adverse effects is emerging. In a single-group observational study with assessments of autonomic system before, during, and after Samadhi meditation, we explore the relationship between post-meditation nausea symptoms and the degree of change in autonomic system activity during meditation as compared to before and after in 57 university students (42 women; mean age = 22...
April 12, 2024: Journal of Religion and Health
#8
JOURNAL ARTICLE
Jingyi Wang, Hua Li, Xuming Huang, Huoyou Hu, Baorong Lian, Daxue Zhang, Jiarui Wu, Liming Cao
BACKGROUND: Syncope is a common condition that increases the risk of injury and reduces the quality of life. Abdominal pain as a precursor to vasovagal syncope (VVS) in adults is rarely reported and is often misdiagnosed.. METHODS: We present three adult patients with VVS and presyncopal abdominal pain diagnosed by synchronous multimodal detection (transcranial Doppler [TCD] with head-up tilt [HUT]) and discuss the relevant literature. RESULTS: Case 1: A 52-year-old man presented with recurrent decreased consciousness preceded by six months of abdominal pain...
April 10, 2024: BMC Neurology
#9
JOURNAL ARTICLE
Shuo Wang, Yali Peng, Yuwen Wang, Fang Li, Yi Xu, Huifen Zheng, Heli Yuan, Chunyan Hu, Donglei Liao, Hong Cai, Juan Zhang, Wen Li, Yiyi Ding, Wenhua Zhang, Xiaohong Xue, Xiaoyan Liu, Liping Zhu, Deyu Liu, Meihua Kang, Liping Liu, Weihong Chu, Xiaoming Li, Xuemei Luo, Runmei Zou, Cheng Wang
OBJECTIVE: Head-up tilt test (HUTT) is an important tool in the diagnosis of pediatric vasovagal syncope. This research will explore the relationship between syncopal symptoms and HUTT modes in pediatric vasovagal syncope. METHODS: A retrospective analysis was performed on the clinical data of 2513 children aged 3-18 years, who were diagnosed with vasovagal syncope, from Jan. 2001 to Dec. 2021 due to unexplained syncope or pre-syncope. The average age was 11.76 ± 2...
April 5, 2024: Cardiology in the Young
#10
JOURNAL ARTICLE
Hongxia Li, Wei Shao, Xia Yu, Lu Gao, Yue Yuan
AIM: Malignant vasovagal syncope in children seriously affects their physical and mental health. Our study aimed to explore the efficacy of catheter ablation in ganglionated plexus with malignant vasovagal syncope children. CONCLUSION: Catheter ablation of ganglionated plexus was safe and effective in children with malignant vasovagal syncope and can be used as a treatment option for these children. METHODS: A total of 20 children diagnosed with malignant vasovagal syncope were enrolled in Beijing Children's Hospital, affiliated with Capital Medical University...
April 4, 2024: Cardiology in the Young
#11
JOURNAL ARTICLE
Mahbuba Ferdowsi, Ban-Hoe Kwan, Maw Pin Tan, Nor' Izzati Saedon, Sukanya Subramaniam, Noor Fatin Izzati Abu Hashim, Siti Sakinah Mohd Nasir, Imran Zainal Abidin, Kok Han Chee, Choon-Hian Goh
BACKGROUND: The diagnostic test for vasovagal syncope (VVS), the most common cause of syncope is head-up tilt test (HUTT) assessment. During the test, subjects experienced clinical symptoms such as nausea, sweating, pallor, the feeling of palpitations, being on the verge of passing out, and fainting. The study's goal is to develop an algorithm to classify VVS patients based on physiological signals blood pressure (BP) and electrocardiography (ECG) obtained from the HUTT. METHODS: After 10 min of supine rest, the subject was tilted at a 70-degree angle on a tilt table for approximately a total of 35 min...
March 30, 2024: Biomedical Engineering Online
#12
JOURNAL ARTICLE
Tolga Aksu, Roderick Tung, Tom De Potter, Timothy M Markman, Pasquale Santangeli, Jeanne du Fay de Lavallaz, Jeffrey R Winterfield, Tina Baykaner, Daniel Alyesh, Jacqueline E Joza, Rakesh Gopinathannair, Patrick Badertscher, Duc H Do, Ayman Hussein, Jose Osorio, Thomas Dewland, Alexander Perino, Albert J Rodgers, Christopher DeSimone, Alberto Alfie, Brett D Atwater, David Singh, Kapil Kumar, Jonathan Salcedo, Jason S Bradfield, Gaurav Upadhyay, Nitesh Sood, Parikshit S Sharma, Sandeep Gautam, Vineet Kumar, Alexander Romeno Janner Dal Forno, Christopher E Woods, Moshe Rav-Acha, Chiara Valeriano, Sunil Kapur, Andres Enriquez, Sri Sundaram, Michael Glikson, Edward Gerstenfeld, Jonathan Piccini, Wendy S Tzou, William Sauer, Andre d'Avila, Kalyanam Shivkumar, Henry D Huang
BACKGROUND: Cardioneuroablation has been emerging as a potential treatment alternative in appropriately selected patients with cardioinhibitory vasovagal syncope (VVS) and functional AV block (AVB). However the majority of available evidence has been derived from retrospective cohort studies performed by experienced operators. METHODS: The Cardioneuroablation for the Management of Patients with Recurrent Vasovagal Syncope and Symptomatic Bradyarrhythmias (CNA-FWRD) Registry is a multicenter prospective registry with cross-over design evaluating acute and long-term outcomes of VVS and AVB patients treated by conservative therapy and CNA...
March 18, 2024: Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing
#13
JOURNAL ARTICLE
Yaqi Li, Baoling Bai, Hui Wang, Haojie Wu, Yanjun Deng, Chen Shen, Qin Zhang, Lin Shi
BACKGROUND: Orthostatic intolerance, which includes vasovagal syncope and postural orthostatic tachycardia syndrome, is common in children and adolescents. Elevated plasma homocysteine levels might participate in the pathogenesis of orthostatic intolerance. This study was designed to analyze the plasma metabolomic profile in orthostatic intolerance children with high levels of plasma homocysteine. METHODS: Plasma samples from 34 orthostatic intolerance children with a plasma homocysteine concentration > 9 µmol/L and 10 healthy children were subjected to ultra-high-pressure liquid chromatography and quadrupole-time-of-flight mass spectrometry analysis...
March 14, 2024: Italian Journal of Pediatrics
#14
JOURNAL ARTICLE
Deepa Baswaraj, Greg Flaker
Athletes are generally healthy but might have certain cardiac disorders which might, during athletic participation or training, result in cardiac symptoms including syncope. Vasovagal syncope is probably the most common cause of syncope in athletes, but syncope in the context of these cardiac disorders might be a warning of sudden death.
2024: Missouri Medicine
#15
JOURNAL ARTICLE
Vincenzo Russo, Angelo Comune, Erika Parente, Anna Rago, Andrea Antonio Papa, Gerardo Nigro, Michele Brignole
BACKGROUND: Approximately 50% of patients with unexplained syncope and negative head-up tilt test (HUTT) who have an electrocardiogram (ECG) documentation of spontaneous syncope during implantable loop recorder (ILR) show an asystolic pause at the time of the event. OBJECTIVE: The aim of the study was to evaluate the age distribution and clinical predictors of asystolic syncope detected by ILR in patients with unexplained syncope and negative HUTT. METHODS: This research employed a retrospective, single-center study of consecutive patients...
February 25, 2024: Clinical Autonomic Research: Official Journal of the Clinical Autonomic Research Society
#16
EDITORIAL
David G Benditt, MaryAnn Goldstein
No abstract text is available yet for this article.
January 23, 2024: JACC. Clinical Electrophysiology
#17
JOURNAL ARTICLE
Yared Paalvast, Niubel Díaz Padilla, Sanne Bruijns, Johanna Wiersum-Osselton, Ties Molenaar
BACKGROUND: Many blood banks use upper age limits for donors out of concern for a higher donor complication rate in older donors. Experienced donors are known to have lower donor complication rates, and older donors are often more experienced, confounding the effect of age on donor complication rate. STUDY DESIGN AND METHODS: We studied donor complication rates in whole blood, plasma, and plateletpheresis donors from 2012 to 2022. Donor complication rates were compared between age groups in inexperienced (<20th donation) and experienced (≥20th donation) donors...
February 22, 2024: Transfusion
#18
JOURNAL ARTICLE
Jacqueline Joza, Luiz Gustavo Bravosi da Rosa, Ahmed Alturki, Valeria Anglesio, Paula Sanchez-Somonte, Vladimir Poletaev, Martin Bernier, Atul Verma, Vidal Essebag
BACKGROUND: Cardioneuroablation (CNA) is an ablation technique that targets epicardial ganglionic plexi to reduce syncope burden and avoid pacemaker implantation in patients with cardioinhibitory vasovagal syncope (VVS). This study aims to demonstrate feasibility and safety of CNA in high-risk refractory VVS patients using continuous monitoring with an implantable loop recorder (ILR). METHODS: Data was collected prospectively for patients undergoing CNA. Patients were required to have recurrent syncope with documented asystole, refractory to conservative measures...
April 2024: IJC Heart & Vasculature
#19
JOURNAL ARTICLE
Naotaka Kishimoto, Tomoaki Ujita, Simon D Tran, Takuro Sanuki, Kenji Seo
INTRODUCTION: As the population ages and more patients experience medical emergencies during dental treatments, dentists must competently and confidently manage these situations. We developed a simulation training course for medical emergencies in the dental setting using an inexpensive vital sign simulation app for smartphones/tablets without the need for an expensive simulator. However, the duration for which this effect is maintained is unclear. This study was performed to evaluate the long-term educational effect at 3, 6, and 12 months after taking the course...
February 20, 2024: European Journal of Dental Education: Official Journal of the Association for Dental Education in Europe
#20
JOURNAL ARTICLE
Vincenzo Russo, Marco Tomaino, Erika Parente, Angelo Comune, Daniele Giacopelli, Paola Napoli, Alessio Gargaro, Michele Brignole
AIMS: Dual-chamber pacemaker with Closed Loop Stimulation (CLS) mode is effective in reducing syncopal recurrences in patients with asystolic vasovagal syncope (VVS). In this study we explored hemodynamic and temporal relationship of CLS during tilt-induced vasovagal reflex. METHODS: Twenty patients underwent tilt test under video recording 3.9 years after CLS pacemaker implantation. RESULTS: Three patients were excluded from the analysis because of no VVS induced by tilt test (n=1) and protocol violation (n=2)...
February 10, 2024: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
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